Accelerated disassembly of IgE–receptor complexes by a disruptive macromolecular inhibitor

Crystal structure of IgE bound to its B-cell receptor CD23 reveals a mechanism of reciprocal allosteric inhibition with high affinity receptor Fc RI

(2012) B. Dhaliwal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of ongoing allergic reactions using a novel anti-IgE DARPin-Fc fusion protein

(2011) A. Eggel et al.   ALLERGY

Conformational changes in IgE contribute to its uniquely slow dissociation rate from receptor FcɛRI

(2011) Mary D Holdom et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

DARPins against a functional IgE epitope

(2010) Michael J. Baumann et al.   IMMUNOLOGY LETTERS

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Conformational Flexibility in Immunoglobulin E-Fc3–4 Revealed in Multiple Crystal Forms

(2009) Beth A. Wurzburg et al.   JOURNAL OF MOLECULAR BIOLOGY

DARPins as Bispecific Receptor Antagonists Analyzed for Immunoglobulin E Receptor Blockage

(2009) Alexander Eggel et al.   JOURNAL OF MOLECULAR BIOLOGY

Fine epitope mapping of humanized anti-IgE monoclonal antibody omalizumab

(2008) Lei Zheng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS