Article
Chemistry, Multidisciplinary
Eleni Kakouri, Dimitra Daferera, Panayiotis Trigas, Despina Charalambous, Maria Pantelidou, Petros A. Tarantilis, Charalabos D. Kanakis
Summary: Hypericum perforatum, an herb with a long history of use, has over-the-counter treatment options for depression. The genus has around 500 species, with antimicrobial resistance becoming a concern as available treatment options become less effective. In this study, nine Hypericum species were examined for their antimicrobial activity and phenolic and flavonoid content.
APPLIED SCIENCES-BASEL
(2023)
Article
Environmental Sciences
Caglayan Unsal Gurer, Esra Eroglu Ozkan, Sukran Kultur, Nurten Ozsoy, Berna Ozbek Celik, Afife Mat
Summary: Endemic Hypericum species in Turkey show significant antioxidant and antibacterial activities, making them valuable in traditional medicine.
FRESENIUS ENVIRONMENTAL BULLETIN
(2022)
Article
Plant Sciences
Xuyang Liu, Xin Cheng, Jingjie Cao, Wenfeng Zhu, Xiaochun Wan, Linlin Liu
Summary: This study identifies the transcription factors CsGLK1 and CsGLK2 as regulators of chlorophyll and flavonoid levels in tea leaves, responding to UV-B signals. They modulate the expression of genes involved in chlorophyll biosynthesis and flavonoid accumulation, leading to UV-B-induced responses in tea leaves. This research sheds new light on the environmental regulations of tea quality and UV-B-induced flavonoid responses in higher plants.
HORTICULTURAL PLANT JOURNAL
(2023)
Article
Agricultural Engineering
Masumeh Karimi, Nima Ahmadi, Morteza Ebrahimi
Summary: The study revealed that increasing the red light fraction in LED light had a positive effect on the growth, flowering, and secondary metabolite accumulation in Hypericum perforatum plants, while higher levels of blue light showed poorer growth and flowering traits. Additionally, antioxidant enzymes activities, total phenolic and flavonoid content were higher in plants exposed to a mixture of red and blue light compared to those grown under white LED light.
INDUSTRIAL CROPS AND PRODUCTS
(2022)
Article
Horticulture
Mozhdeh Shafaei, Morteza Ebrahimi, Mahmoud Khosrowchahli, Eslam Majidi Heravan, Reza Azizinezhad
Summary: The study aimed to establish a system for studying the production of hypericin in adventitious root lines of Hypericum perforatum L. Several factors including medium consistency and auxin type were investigated for their effects on the induction of adventitious roots from leaf explants. It was found that a half-strength MS liquid medium with 2 mg/L of IBA concentration was optimal for adventitious root development, while NAA and IAA resulted in callus-like structures and low branch roots. HPLC-UV analysis was employed to assess hypericin content variations in 100 adventitious root lines, and five elite lines with high hypericin production were identified.
JOURNAL OF HORTICULTURAL SCIENCE & BIOTECHNOLOGY
(2023)
Article
Environmental Sciences
Jianhua Wang, Mingwei Li, Jinlin Feng, Xiaoyan Yan, Huize Chen, Rong Han
Summary: The study showed that pretreatment with TiO2-NPs can alleviate UV-B stress on plants by promoting flavonoid synthesis, improving the antioxidant system, and preventing depolymerization of microtubules, with a safe and effective application dose of 10 mg/L.
Article
Agricultural Engineering
Matam Pradeep, Gregory Franklin
Summary: Inhibition of hypericin biosynthesis can be achieved by impairing the dark glands responsible for synthesizing and accumulating hypericin, with the ability to recover biosynthesis by withdrawing the inhibiting agent glyphosate. The expression of key genes involved in hypericin biosynthesis, such as polyketide synthases and phenolic oxidative coupling proteins, is regulated by glyphosate treatment and withdrawal.
INDUSTRIAL CROPS AND PRODUCTS
(2022)
Article
Plant Sciences
Hongyan Su, Ling Jin, Mengfei Li, Paul W. Pare
Summary: Plants of St John's wort grown at cooler temperatures exhibit changes in leaf anatomy and gene expression, which support the plant's ability to accumulate enhanced levels of the anti-depression compound hypericin at low temperatures.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Food Science & Technology
Yoon A. Jeon, Sun Woo Chung, Seong Cheol Kim, Young Jae Lee
Summary: This study evaluated the antioxidant and anti-inflammatory properties of papaya fruit extracts and found that they exhibited high antioxidant and anti-inflammatory activities. In particular, the ripe seed extracts showed significant inhibition of NO production, which may be associated with the suppression of NF-kappa B activation and iNOS expression. Therefore, papaya fruit extracts can be potential raw materials for functional foods.
Article
Pharmacology & Pharmacy
Ilioara Oniga, Anca Toiu, Daniela Benedec, Laurian Vlase
Summary: The present research compared the phytochemical composition of Hypericum perforatum and H. hirsutum from different areas. The results showed that H. perforatum had higher levels of bioactive compounds compared to H. hirsutum, and there were significant chemical differences between the two species.
Article
Food Science & Technology
Mian Wang, Chaoqun Leng, Yahui Zhu, Pei Wang, Zhenxin Gu, Runqiang Yang
Summary: UV-B treatment significantly increased the content of phenolic acids in barley seedlings, while also boosting the activity of related enzymes and gene expression levels, leading to an improved antioxidant system.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Plant Sciences
Cuneyt Cirak, Fatih Seyis
Summary: In this study, the qualitative and quantitative analysis of 16 phenolic compounds in under-exploited Turkish Hypericum species was conducted using HPLC for the first time. The results showed variations in compound levels depending on species and populations. Hierarchical cluster analysis and principal component analysis were used to differentiate samples based on geographical origin and botanical classification. The findings provide valuable data for clarifying evolutionary relationships and further research in chemotaxonomy and pharmacognosy of the Hypericum genus.
SOUTH AFRICAN JOURNAL OF BOTANY
(2023)
Article
Biochemical Research Methods
Borivoj Adnadjevic, Biljana Koturevic, Jelena Jovanovic
Summary: This study aimed to investigate the kinetics of extracting total hypericin from Hypericum perforatum flowers, finding that the Jander three-dimensional diffusion model best described the extraction process. The calculation of kinetic parameters and identification of the controlling step provide important insights for the extraction process.
PHYTOCHEMICAL ANALYSIS
(2021)
Article
Horticulture
Wenna Zhen, Yi Tu, Zihan Lin, Xinxin Xu, Maorun Fu, Cong Han
Summary: UV-B irradiation synergistically enhances the accumulation of phenolic antioxidants in wounded carrots and promotes the activity of phenylalanine ammonia lyase (PAL) and the biosynthesis of phenolic compounds. Transcriptome analysis revealed that UV-B treatment accelerates signal transduction and secondary substance metabolism.
Article
Plant Sciences
Kalina Danova, Vaclav Motyka, Antoaneta Trendafilova, Petre Dobrev, Viktorya Ivanova, Ina Aneva
Summary: The growth, development, hypericin content and endogenous phytohormone levels were investigated in different stages of evolution of Hypericum plants. The evolutionarily youngest H. richeri had the highest hypericin productivity in vitro, while the evolutionarily oldest H. calycinum had the highest content of salicylic acid and total jasmonates in some treatments.
Meeting Abstract
Biochemical Research Methods
Engin Tilkat, Ahmet Onay, Yelda Ozden, Hakan Yildirim, Emine Ayaz Tilkat
CURRENT OPINION IN BIOTECHNOLOGY
(2011)
Article
Plant Sciences
Orazio Taglialatela-Scafati, Federica Pollastro, Lavinia Cicione, Giuseppina Chianese, Maria Luz Bellido, Eduardo Munoz, Hasan Cetin Ozen, Zuhal Toker, Giovanni Appendino
JOURNAL OF NATURAL PRODUCTS
(2012)
Article
Chemistry, Applied
Emine Ayaz, Suereyya Namli
NATURAL PRODUCT RESEARCH
(2009)
Article
Plant Sciences
Zuhal Toker
PHARMACEUTICAL BIOLOGY
(2009)
Article
Horticulture
Engin Tilkat, Ahmet Onay, Hakan Yildirim, Emine Ayaz
SCIENTIA HORTICULTURAE
(2009)
Article
Agronomy
Emine Ayaz Tilkat, Hayri Batibay, Ismail Yener, Pelin Koseoglu Yilmaz, Mehmet Akdeniz, Alevcan Kaplan, Sezai Ercisli, Abdulselam Ertas, Vojtech Holubec
Summary: The study investigated the biological activities of Pistacia khinjuk Stocks samples in terms of antihypertensive, anticholinesterase, antiurease, antityrosinase, antielastase enzyme inhibition, and anticancer activities. The results showed that the female root parts of in vivo samples exhibited better cytotoxic effects against MCF-7 and HT-29 cancer cell lines.
Article
Chemistry, Analytical
Emine Ayaz-Tilkat
Summary: The study focused on elucidating the biosynthesis of cytotoxic triterpenoids through in vitro micropropagation of Pistacia khinjuk Stocks with different NaCl concentrations. Results showed an increase in triterpenoid content in plant parts with high NaCl concentrations, leading to a reduction in morpho-physiological properties of the plant materials. This indicates that the production of secondary compounds, specifically triterpenoids, was favored over primary compounds in response to increased salt concentrations.
JOURNAL OF CHEMICAL METROLOGY
(2021)
Article
Plant Sciences
Emine Ayaz Tilkat, Nesrin Hasimi, Ibrahim S. Kuru, Veysel Suzerer
NOTULAE BOTANICAE HORTI AGROBOTANICI CLUJ-NAPOCA
(2020)
Article
Biotechnology & Applied Microbiology
Toker Zuhal, Karakas Ozgur, Ozen Hasan Cetin
RESEARCH JOURNAL OF BIOTECHNOLOGY
(2015)
Article
Agronomy
Emine Ayaz Tilkat, Sureyya Namli, Cigdem Isikalan
AUSTRALIAN JOURNAL OF CROP SCIENCE
(2011)
Article
Chemistry, Multidisciplinary
Emine Ayaz, Suereyya Namli
ASIAN JOURNAL OF CHEMISTRY
(2009)
Review
Biology
Ahmet Onay, Abdulselam Ertas, Veysel Suzerer, Ismail Yener, Mustafa Abdullah Yilmaz, Emine Ayaz-Tilkat, Remzi Ekinci, Nesrin Bozhan, Sevgi Irtegun-Kandemir
Summary: The endocannabinoid system (ECS) plays a crucial role in regulating various physiological functions and controlling pharmacological activities. Cannabinoids, particularly CBD, are believed to have potential therapeutic effects in treating patients infected with the novel coronavirus.
TURKISH JOURNAL OF BIOLOGY
(2021)
Article
Plant Sciences
Suereyya Namli, Filiz Akbas, Cigdem Isikalan, Emine Ayaz Tilkat, Davut Basaran