Article
Plant Sciences
Kiran Khandagale, Praveen Roylawar, Onkar Kulkarni, Pravin Khambalkar, Avinash Ade, Abhijeet Kulkarni, Major Singh, Suresh Gawande
Summary: Through RNAseq analysis, we identified differentially expressed genes in onion in response to Purple Blotch (PB) infection caused by Alternaria porri. These genes are involved in defense responses, signaling, and other molecular mechanisms. This study provides valuable insights for understanding the interaction between onion and A. porri, as well as improving PB resistance in onions.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Microbiology
Lin Zhao, Huan Luo, Hong Cheng, Ya-Nan Gou, Zhi-He Yu, Jian-Xin Deng
Summary: Alternaria is a diverse fungal genus associated with various substrates, including important plant pathogens. A study in China discovered 13 large-spored Alternaria species, including five new species, and identified three species for the first time in China.
Article
Engineering, Environmental
Rongrong Gao, Rui Liu, Chaomin Sun
Summary: Huge quantities of plastic wastes pose serious ecological problems and impact global carbon cycling. Researchers have successfully isolated a fungus named Alternaria alternata FB1 from plastic waste samples, which showed remarkable degradation capabilities on polyethylene (PE) film. This discovery provides a promising candidate for further investigation of degradation mechanisms and development of biodegradable products.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Multidisciplinary Sciences
Min Young Kim, Jae Woo Han, Quang Le Dang, Jin-Cheol Kim, Hun Kim, Gyung Ja Choi
Summary: This study optimized the conditions for spore production and disease development of Alternaria porri and screened plant extracts for potent antifungal activity. Magnolol, identified from the methanol extract of Caryodaphnopsis baviensis, exhibited significant inhibitory activity against A. porri and showed efficacy in controlling purple blotch disease on onion plants.
Article
Plant Sciences
Guillaume Quang N'Guyen, Roxane Raulo, Antoine Porquier, Beatrice Iacomi, Sandra Pelletier, Jean-Pierre Renou, Nelly Bataille-Simoneau, Claire Campion, Bruno Hamon, Anthony Kwasiborski, Justine Colou, Abdelilah Benamar, Pietrick Hudhomme, David Macherel, Philippe Simoneau, Thomas Guillemette
Summary: This study indicates that the indolic phytoalexin primarily targets mitochondrial functions in fungal cells. Treatment of A. brassicicola with phytoalexin disrupted the mitochondrial membrane potential and led to a significant and rapid decrease in oxygen consumption rates. Secondary effects, such as Reactive oxygen species production, changes in lipid and endoplasmic reticulum homeostasis were induced. Consequently, the fungus has to adapt its metabolism to protect itself against the toxic effects of these molecules, especially via the activation of high osmolarity glycerol and cell wall integrity signaling pathways and by induction of the unfolded protein response.
FRONTIERS IN PLANT SCIENCE
(2021)
Article
Chemistry, Applied
Ju-Tao Wang, Zong-Hui Ma, Guo-Kai Wang, Feng-Qing Xu, Yang Yu, Gang Wang, Dai-Yin Peng, Jin-Song Liu
Summary: Nine compounds were isolated from the endophyte of Paeonia lactiflora, Alternaria alternata, including five new natural compounds and four known ones. Structural elucidation was achieved through intensive analysis of spectroscopic data. Some of the compounds exhibited cytotoxic activities against selected human tumour cell lines.
NATURAL PRODUCT RESEARCH
(2021)
Article
Biochemistry & Molecular Biology
Fengli Li, Zi Ye, Zhangyan Huang, Xia Chen, Weiguang Sun, Weixi Gao, Sitian Zhang, Fei Cao, Jianping Wang, Zhengxi Hu, Yonghui Zhang
Summary: Three pairs of undescribed enantiomeric alpha-pymne derivatives and six undescribed congeners were isolated from the fungus Alternaria brassicicola. These compounds were evaluated for herbicidal activity against various weeds, showing promising results comparable to the positive control glyphosate. The study provides insights on the structure-herbicidal activity relationship and opens up opportunities for the practical application of fungal metabolites as ecofriendly herbicides.
BIOORGANIC CHEMISTRY
(2021)
Article
Biology
Harshvardhan Dattatray Gaikwad, Sunil Govind Dalvi, Shrihari Hasabnis, Penna Suprasanna
Summary: The study demonstrates that irradiated chitosan can enhance resistance responses against purple blotch disease in onions by increasing antioxidant enzymes and metabolites. This suggests potential value addition for onions as a food commodity.
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
(2022)
Article
Plant Sciences
Zoha Daroodi, Parissa Taheri, Saeed Tarighi
Summary: In this study, the efficiency of the endophytic fungal isolate Msh5 on promoting tomato plant growth and controlling Alternaria alternata was evaluated. The results showed that Msh5 was capable of producing beneficial substances and inhibiting the growth of A. alternata. Under laboratory conditions, Msh5 could reduce spore germination and alter the hyphal structure of A. alternata. In plant experiments, Msh5 significantly increased plant growth and reduced diseases caused by A. alternata.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Plant Sciences
Chia-Hao Chang, Yi-Chieh Lee, George Hsiao, Li-Kwan Chang, Wei-Chiung Chi, Yuan-Chung Cheng, Shu-Jung Huang, Tai-Chou Wang, Yi-Shan Lu, Tzong-Huei Lee
Summary: This study investigated the liquid-state fermented products produced by the fungal strain Alternaria alstroemeriae Km2286 isolated from the medicinal herb Atriplex maximowicziana Makino. Chromatographic separation resulted in the isolation of compounds 1-9, including four undescribed perylenequinones. Compound 1-6 exhibited antiviral activities against Epstein-Barr virus and compounds 1-4, 6, and 7 showed inhibitory activity of nitric oxide production in lipopolysaccharide-induced microglial BV-2 cells without significant cytotoxicity. This is the first report of perylenequinone-type compounds with potent anti-EBV and anti-neuroinflammatory activities.
JOURNAL OF NATURAL PRODUCTS
(2022)
Article
Virology
Wenqing Wang, Xianhong Wang, Chunyan Tu, Mengmeng Yang, Jun Xiang, Liping Wang, Ni Hong, Lifeng Zhai, Guoping Wang
Summary: This study used total RNA sequencing to identify and characterize viruses in Alternaria fungi. 12 different mycoviruses were discovered, including positive-sense single-stranded RNA, double-strand RNA, and negative single-stranded RNA viruses. Five of these viruses were classified as novel mycoviruses in various virus families. Additionally, a novel -ssRNA virus and a novel +ssRNA virus were identified and their phylogenetic relationships were determined.
Article
Biotechnology & Applied Microbiology
Zhe Guo, Ruiyun Huo, Shubin Niu, Xingzhong Liu, Ling Liu
Summary: A new cytochalasin, Alternariasin A, and five known compounds were isolated from the solid cultures of the fungus Alternaria alternata derived from the Midui Glacier. Alternariasin A exhibited antibacterial activity against S. aureus, B. subtilis, and E. coli, while compound 3 showed potent cytotoxicity against a small panel of human tumor cell lines.
JOURNAL OF ANTIBIOTICS
(2021)
Article
Biochemistry & Molecular Biology
Xiaoyuan Tang, Yuxuan Zhao, Xude Wang, Chongtao Ye, Baomin Feng, Chuan Tang, Xuan Lu
Summary: Seven undescribed polyketides with unique structures were isolated from Rhodiola tibetica endophytic fungus Alternaria sp. HJT-Y7. The structures of these compounds were determined using NMR and HR-ESI-MS analysis. Two undescribed compounds and four known compounds demonstrated significant inhibitory effects on LPS-induced NO production in cells without cytotoxicity.
Article
Plant Sciences
Thibault Barrit, Alexis Porcher, Caroline Cukier, Pascale Satour, Thomas Guillemette, Anis M. Limami, Beatrice Teulat, Claire Campion, Elisabeth Planchet
Summary: This study examined the impact of nitrogen source on the susceptibility to an necrotrophic fungus in Arabidopsis thaliana. The results showed that nitrate nutrition increased fungal lesions considerably, while infection with the fungus induced stronger gene expression of ammonium transporters in ammonium-grown plants. Nitrogen source also affected plant metabolism and the production of nitric oxide, which facilitated fungal infection. The study highlighted the complex relationship between nitrogen availability and disease susceptibility in plants.
PHYSIOLOGIA PLANTARUM
(2022)
Review
Agronomy
Domingo Cesar Carrascal-Hernandez, Edwin Florez-Lopez, Yeimmy Peralta-Ruiz, Clemencia Chaves-Lopez, Carlos David Grande-Tovar
Summary: Postharvest diseases, especially those caused by Alternaria species, have a significant impact on agricultural food production worldwide. Traditional management of these diseases relies heavily on the use of fungicides, which have negative effects on the environment and human health. However, recent advancements in 'omics' technologies, gene editing using CRISPR/Cas9 system and RNAi technologies, as well as the development of coatings based on essential oils and microbial antagonists, offer promising greener alternatives for controlling phytopathogenic fungi.
