Isolation, biological activity, synthesis, and medicinal chemistry of the pederin/mycalamide family of natural products

The protein synthesis inhibitors mycalamides A and E have limited susceptibility toward the drug efflux network

(2011) Veronica Venturi et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Total Synthesis and Biological Evaluation of Pederin, Psymberin, and Highly Potent Analogs

(2011) Shuangyi Wan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereoselective Synthesis of 2,6-trans-Tetrahydropyran via Primary Diamine-Catalyzed Oxa-Conjugate Addition Reaction of α,β-Unsaturated Ketone: Total Synthesis of Psymberin

(2011) Seong Rim Byeon et al.   ORGANIC LETTERS

Inhibition of eukaryotic translation elongation by the antitumor natural product Mycalamide B

(2011) Y. Dang et al.   RNA

Temporary Restraints To Overcome Steric Obstacles: An Efficient Strategy for the Synthesis of Mycalamide B

(2010) John C. Jewett et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Total Synthesis of Pederin and Analogues

(2010) Fanghui Wu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Syntheses and Biological Evaluation of Irciniastatin A and the C1−C2 Alkyne Analogue

(2010) Tsubasa Watanabe et al.   ORGANIC LETTERS

Irciniastatin A induces JNK activation that is involved in caspase-8-dependent apoptosis via the mitochondrial pathway

(2010) Takumi Chinen et al.   TOXICOLOGY LETTERS

Structures of Triacetyloleandomycin and Mycalamide A Bind to the Large Ribosomal Subunit of Haloarcula marismortui

(2009) G. Gurel et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Chemoenzymatic Synthesis of (Protected) Psymberic Acid

(2009) Jörg Pietruszka et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Pederin-Type Pathways of Uncultivated Bacterial Symbionts: Analysis ofO-Methyltransferases and Generation of a Biosynthetic Hybrid

(2009) Katrin Zimmermann et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Polyketide assembly lines of uncultivated sponge symbionts from structure-based gene targeting

(2009) Katja M Fisch et al.   Nature Chemical Biology

The Discovery of Potent Antitumor Agent C11-Deoxypsymberin/irciniastatin A: Total Synthesis and Biology of Advanced Psymberin Analogs

(2009) Xianhai Huang et al.   ORGANIC LETTERS

Total Synthesis of Irciniastatin A (Psymberin)

(2009) Michael T. Crimmins et al.   ORGANIC LETTERS

New Applications of PhI(OAc)2 in Synthesis: Total Synthesis and SAR Development of Potent Antitumor Natural Product Psymberin/Irciniastatin A

(2009) Ning Shao et al.   SYNTHESIS-STUTTGART

First total synthesis of theopederin B

(2009) Yoshinori Nishii et al.   TETRAHEDRON LETTERS

Total Synthesis of Theopederin D

(2008) Michael E. Green et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Total Synthesis of (+)-Psymberin (Irciniastatin A): Catalytic Reagent Control as the Strategic Cornerstone

(2008) Amos B. Smith et al.   ORGANIC LETTERS