Neoplastic-like transformation effect of single-walled and multi-walled carbon nanotubes compared to asbestos on human lung small airway epithelial cells

ECVAM prevalidation of three cell transformation assays

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Asbestos-Induced Cellular and Molecular Alteration of Immunocompetent Cells and Their Relationship with Chronic Inflammation and Carcinogenesis

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Multiwalled Carbon Nanotube-Induced Gene Signatures in the Mouse Lung: Potential Predictive Value for Human Lung Cancer Risk and Prognosis

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Photo catalogue for the classification of foci in the BALB/c 3T3 cell transformation assay

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Reactive oxygen species-mediated p38 MAPK regulates carbon nanotube-induced fibrogenic and angiogenic responses

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Morphological transformation induced by multiwall carbon nanotubes on Balb/3T3 cell model as anin vitroend point of carcinogenic potential

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Chronic occupational exposure to arsenic induces carcinogenic gene signaling networks and neoplastic transformation in human lung epithelial cells

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Mechanisms of carbon nanotube-induced toxicity: Focus on oxidative stress

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Long, Needle-like Carbon Nanotubes and Asbestos Activate the NLRP3 Inflammasome through a Similar Mechanism

(2011) Jaana Palomäki et al.   ACS Nano

Direct Effects of Carbon Nanotubes on Dendritic Cells Induce Immune Suppression Upon Pulmonary Exposure

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Dispersal State of Multiwalled Carbon Nanotubes Elicits Profibrogenic Cellular Responses That Correlate with Fibrogenesis Biomarkers and Fibrosis in the Murine Lung

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Length-Dependent Retention of Carbon Nanotubes in the Pleural Space of Mice Initiates Sustained Inflammation and Progressive Fibrosis on the Parietal Pleura

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Toxicogenomic comparison of multi-wall carbon nanotubes (MWCNTs) and asbestos

(2011) Jin Sik Kim et al.   ARCHIVES OF TOXICOLOGY

Hallmarks of Cancer: The Next Generation

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Non-Neoplastic and Neoplastic Pleural Endpoints Following Fiber Exposure

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Cell transformation assays for prediction of carcinogenic potential: state of the science and future research needs

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Carbon Nanotubes Induce Malignant Transformation and Tumorigenesis of Human Lung Epithelial Cells

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Cellular uptake mechanisms of functionalised multi-walled carbon nanotubes by 3D electron tomography imaging

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(2011) Robert R Mercer et al.   Particle and Fibre Toxicology

Diameter and rigidity of multiwalled carbon nanotubes are critical factors in mesothelial injury and carcinogenesis

(2011) H. Nagai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multi-walled carbon nanotube-induced gene expression in the mouse lung: Association with lung pathology

(2011) M. Pacurari et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Caspase-8 activity has an essential role in CD95/Fas-mediated MAPK activation

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Asbestos, Lung Cancers, and Mesotheliomas

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Review of carbon nanotubes toxicity and exposure—Appraisal of human health risk assessment based on open literature

(2010) Karin Aschberger et al.   CRITICAL REVIEWS IN TOXICOLOGY

Asbestos, carbon nanotubes and the pleural mesothelium: a review and the hypothesis regarding the role of long fibre retention in the parietal pleura, inflammation and mesothelioma

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Distribution and persistence of pleural penetrations by multi-walled carbon nanotubes

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Dispersion of single-walled carbon nanotubes by a natural lung surfactant for pulmonary in vitro and in vivo toxicity studies

(2010) Liying Wang et al.   Particle and Fibre Toxicology

Comparative Proteomics and Pulmonary Toxicity of Instilled Single-Walled Carbon Nanotubes, Crocidolite Asbestos, and Ultrafine Carbon Black in Mice

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Uptake and cytotoxic effects of multi-walled carbon nanotubes in human bronchial epithelial cells

(2010) Seishiro Hirano et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

A comparison of acute and long-term effects of industrial multiwalled carbon nanotubes on human lung and immune cells in vitro

(2010) Tina Thurnherr et al.   TOXICOLOGY LETTERS

Chromosomal and genomic changes in lung cancer

(2010) Marileila Varella-Garcia   Cell Adhesion & Migration

DNA Double-Strand Breaks by Asbestos, Silica, and Titanium Dioxide

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Host-Derived Tumor Endothelial Marker 8 Promotes the Growth of Melanoma

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Induction of aneuploidy by single-walled carbon nanotubes

(2009) L.M. Sargent et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Mechanisms for how inhaled multiwalled carbon nanotubes suppress systemic immune function in mice

(2009) L. A. Mitchell et al.   Nature Nanotechnology

Lung inflammation and genotoxicity following pulmonary exposure to nanoparticles in ApoE-/- mice

(2009) Nicklas Jacobsen et al.   Particle and Fibre Toxicology

Mouse pulmonary dose- and time course-responses induced by exposure to multi-walled carbon nanotubes

(2009) Dale W. Porter et al.   TOXICOLOGY

Asbestos-induced lung diseases: an update

(2009) David W. Kamp   Translational Research

Novel functional view of the crocidolite asbestos-treated A549 human lung epithelial transcriptome reveals an intricate network of pathways with opposing functions

(2008) Joan M Hevel et al.   BMC GENOMICS

Raw Single-Wall Carbon Nanotubes Induce Oxidative Stress and Activate MAPKs, AP-1, NF-κB, and Akt in Normal and Malignant Human Mesothelial Cells

(2008) Maricica Pacurari et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

The many faces of PPARγ: Anti-inflammatory by any means?

(2008) Attila Szanto et al.   IMMUNOBIOLOGY

Induction of mesothelioma in p53+/− mouse by intraperitoneal application of multi-wall carbon nanotube

(2008) Atsuya Takagi et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Inflammation and Lung Cancer: Roles of Reactive Oxygen/Nitrogen Species

(2008) Neelam Azad et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS

Single-Walled Carbon Nanotubes Can Induce Pulmonary Injury in Mouse Model

(2008) Cheng-Chung Chou et al.   NANO LETTERS

Somatic mutations affect key pathways in lung adenocarcinoma

(2008) Li Ding et al.   NATURE

Carbon nanotubes introduced into the abdominal cavity of mice show asbestos-like pathogenicity in a pilot study

(2008) Craig A. Poland et al.   Nature Nanotechnology

Mechanisms of pulmonary toxicity and medical applications of carbon nanotubes: Two faces of Janus?

(2008) A.A. Shvedova et al.   PHARMACOLOGY & THERAPEUTICS

Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica

(2008) C. Dostert et al.   SCIENCE

SWCNT suppress inflammatory mediator responses in human lung epithelium in vitro

(2008) Eva Herzog et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Genotoxicity of nanomaterials: DNA damage and micronuclei induced by carbon nanotubes and graphite nanofibres in human bronchial epithelial cells in vitro

(2008) Hanna K. Lindberg et al.   TOXICOLOGY LETTERS

Alteration of deposition pattern and pulmonary response as a result of improved dispersion of aspirated single-walled carbon nanotubes in a mouse model

(2007) R. R. Mercer et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Sequential Exposure to Carbon Nanotubes and Bacteria Enhances Pulmonary Inflammation and Infectivity

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