Article
Chemistry, Multidisciplinary
Amirsadra Ahmadi, Moses Sokunbi, Trisha Patel, Ming-Wei Chang, Zeeshan Ahmad, Neenu Singh
Summary: This study statistically analyzed the factors influencing the biocompatibility and toxicity of Mesoporous Silica Nanoparticles (MSNs) in the past five years, including physicochemical properties, experimental conditions, and other experimental parameters.
Article
Nanoscience & Nanotechnology
Rachel M. McDougall, Hannah F. Cahill, Madeline E. Power, Tyson J. MacCormack, M-Vicki Meli, Jillian L. Rourke
Summary: This study investigated the cytotoxic properties of gold nanoparticles (AuNP) conjugated to different ligands. The results showed that the surface chemistry of AuNP affected the magnitude and mechanism of cell death.
Article
Environmental Sciences
Pabel Cervantes-Aviles, Ayman N. Saber, Abrahan Mora, Jurgen Mahlknecht, German Cuevas-Rodriguez
Summary: The effects of titanium dioxide nanoparticles on nitrogen and phosphorus removal in different types of wastewaters varied, depending on the organic matter and ammonia content in the wastewater. Additionally, the nanoparticles were found to interact with activated sludge flocs by adsorbing onto cell membranes, potentially disrupting the treatment process.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Review
Engineering, Chemical
Jesus Roberto Vargas-Ortiz, Carmen Gonzalez, Karen Esquivel
Summary: This review discusses the role, physicochemical properties, potential applications, and toxicological effects of magnetic nanoparticles (MNPs) in complex biological systems. MNPs have been widely used in various industries, leading to increased interactions with biological organisms. However, the full impact of these particles on complex biological systems and the toxicology aspects of their biomedical applications remain unclear, with mixed and inconclusive results. A consolidative framework that considers the physicochemical properties and potential risks of MNPs is necessary for their future manageable applications.
Review
Pharmacology & Pharmacy
Anas Ahmad, Mohammad Imran, Nisha Sharma
Summary: The assessment of human and environmental risks of nanoparticulate material is crucial and requires the development of scientific tools and techniques. Challenges exist in toxicology assessment and regulatory guidance for nanocarriers. Nanotoxicology plays a significant role in pharmaceutical drug development and commercialization potential.
Article
Chemistry, Multidisciplinary
Xin Zhang, Jinxu Zhang, Hua Yang, Chunyong He, Yubin Ke, Seema Singh, Gang Cheng
Summary: This study extracted lignins from different plants to establish a general pattern of their structure in several solvents. Small-angle neutron scattering was used to observe lignin molecules and aggregates. The study obtained important factors affecting the uses of LNPs from SANS data for the first time, and discovered a large hydration shell around LNPs in aqueous solutions.
Article
Food Science & Technology
Aline Castro Silva, Alisson Gleysson Rodrigues dos Santos, Joana Claudio Pieretti, Wallace Rosado Rolim, Amedea Barozzi Seabra, Daiana Silva Avila
Summary: Fe3O4@Ag-NPs nanoparticles showed reprotoxicity, cholinergic neurotoxicity, and activation of the antioxidant system in C. elegans, suggesting their potential harm to living organisms.
FOOD AND CHEMICAL TOXICOLOGY
(2023)
Article
Environmental Sciences
Xiaoqiong Cao, Xiaoyong Pan, Sneha P. Couvillion, Tong Zhang, Carlos Tamez, Lisa M. Bramer, Jason C. White, Wei-Jun Qian, Brian D. Thrall, Kee Woei Ng, Xiao Hu, Philip Demokritou
Summary: The study investigated the fate of iron and copper-doped carbon dots during digestion, with higher dissolution rate observed for copper. Copper-doped carbon dots were found to induce a series of toxic effects, including decreased cell viability and alterations in metabolites.
Article
Environmental Sciences
Yanfei Zhou, Gang He, Hao Jiang, Ke Pan, Wenzhi Liu
Summary: The study found that nanoplastics have toxic effects on soil fauna (earthworms), including decreased antioxidant enzyme activity, accumulation of reactive oxygen species, reduced growth rate, and pathological abnormalities. These adverse effects are enhanced by positively charged nanoplastics. Moreover, the nanoplastics can enter earthworm cells and accumulate in lysosomes, leading to cellular death. These findings have important implications for assessing the ecological risk of nanoplastics.
ENVIRONMENT INTERNATIONAL
(2023)
Review
Chemistry, Multidisciplinary
Patrycja Talarska, Maciej Boruczkowski, Jakub Zurawski
Summary: Silver and gold nanoparticles are widely used in various household products, raising concerns about their potential impact. Research is focusing on the effects of nanoparticles on cell function and environmentally friendly alternatives to chemically synthesized nanoparticles.
Article
Oncology
Serenella Medici, Massimiliano Peana, Alessio Pelucelli, Maria Antonietta Zoroddu
Summary: Despite the increasing number and variety of nanoparticles, there is still a lack of clear guidelines to control their exposure and evaluate potential toxicity. The issue of nanomaterials' toxicity is gaining awareness among scientists and producers, yet consumers often remain largely unaware of the presence and potential risks of nanomaterials.
SEMINARS IN CANCER BIOLOGY
(2021)
Article
Biotechnology & Applied Microbiology
Hyeyoun Chang, Ji Young Yhee, Sangmin Jeon, Man Kyu Shim, Hong Yeol Yoon, Sangmin Lee, Kwangmeyung Kim
Summary: Repeated high-dose administration of CNPs in healthy mice induces severe cardiotoxicity, including inflammatory responses, tissue damages, fibrotic changes, and organ dysfunction.
JOURNAL OF NANOBIOTECHNOLOGY
(2023)
Review
Chemistry, Multidisciplinary
Catia Domingues, Ana Santos, Carmen Alvarez-Lorenzo, Angel Concheiro, Ivana Jarak, Francisco Veiga, Isabel Barbosa, Marilia Dourado, Ana Figueiras
Summary: Worldwide development and application of nanotechnology have led to significant scientific advancements. It is important to balance the high expectations and concerns associated with this field. Nanomedicine, a specific arm of nanotechnology, focuses on the diagnosis, treatment, and monitoring of various diseases. However, the concept of nanotoxicology has also emerged as a crucial aspect of nanomedicine. More research is needed to identify potential adverse effects and ensure the safety of nanomedicines.
Article
Materials Science, Multidisciplinary
J. Cancino-Bernardi, P. M. P. Lins, V. S. Marangoni, H. A. M. Faria, V. Zucolotto
Summary: This study investigates the interactions between gold-based nanoparticles and natural cell membranes, showing that the lipidic composition of different cell types affects the pathway of nanoparticles through the cell membrane. Additionally, the surface charge of nanoparticles plays a significant role in their ability to interact with cell membranes, as demonstrated by isothermal titration calorimetry and atomic force microscopy analysis.
MATERIALS TODAY COMMUNICATIONS
(2021)
Article
Engineering, Environmental
Shilpa Mishra, Baranidharan Sundaram
Summary: The development and expansion of various nanoparticles without standardized laws or guidelines could result in unfavorable environmental changes and impact employees in both interior and exterior working environments.
PROCESS SAFETY AND ENVIRONMENTAL PROTECTION
(2023)
Article
Chemistry, Applied
Juan I. Mirena, Denis Constales, Johan Martens, Jolien Dendooven, Gregory S. Yablonsky, Vladimir V. Galvita
Summary: The study reveals the complex dynamic behavior of CO oxidation over a Pt catalyst in heterogeneous catalysis. It shows that critical phenomena in such systems are influenced by surface interactions, nonlinear reaction mechanisms, and the transport of energy and mass. The pulse experiments conducted with a TAP reactor demonstrate the dependence of the dynamic patterns on the pulsed CO/O2 ratio and the local bed temperature, resulting in a dynamic transition between two critical values of the reaction rate for feed mixtures richer in O2 due to controlled interactions of adsorbed species on the catalyst's surface.
Article
Engineering, Chemical
Maarten Houlleberghs, Loes Verheyden, Filip Voorspoels, C. Vinod Chandran, Karel Duerinckx, Sambhu Radhakrishnan, Johan A. Martens, Eric Breynaert
Summary: Magnetohydrodynamic mixing was evaluated as an alternative method to conventional high shear mixing for preparing carbomer hydrogels. Results showed that magnetohydrodynamic mixing can adjust the viscosity of the hydrogel and achieve higher concentrations of TEA.
Review
Cell Biology
Nirosha Ganesan, Steven Ronsmans, Peter Hoet
Summary: The ability to monitor lymphocyte responses is crucial for understanding the immune response in humans. The current method, using [H-3] thymidine incorporation, has limitations in accurately measuring cell proliferation. There are several alternative techniques, most notably flow cytometry, that have shown promising results in measuring lymphocyte proliferation. This review evaluates these alternatives and their compatibility with the [H-3] thymidine method to identify the best replacement.
Article
Chemistry, Multidisciplinary
Karel Asselman, Mohamed Haouas, Maarten Houlleberghs, Sambhu Radhakrishnan, Wauter Wangermez, Christine E. A. Kirschhock, Eric Breynaert
Summary: Recently discovered zeolite precursors, hydrated silicate ionic liquids (HSIL), simplify the study of zeolite crystallization by minimizing the correlation of synthesis variables and elucidating the role of water. By conducting hydrothermal treatment of Al-doped potassium HSIL, porous merlinoite (MER) zeolite is formed when H2O/KOH exceeds 4, while dense, anhydrous megakalsilite is formed when H2O/KOH is lower. The selectivity of phase formation is determined by cation hydration, water activity, and affinity to coordinate with aluminosilicate or water.
CRYSTAL GROWTH & DESIGN
(2023)
Review
Environmental Sciences
Aala Azari, Jeroen A. J. Vanoirbeek, Frank Van Belleghem, Brent Vleeschouwers, Peter H. M. Hoet, Manosij Ghosh
Summary: The pervasive pollution of microplastics and nano plastics (M/NPs) in indoor and outdoor atmospheres poses difficulties for comparing their prevalence due to various methodologies and non-standardization. This review extracts data from PubMed and Embase databases to analyze sampling strategies, identification methods, and reporting data for quantifying M/NPs. It primarily focuses on different methods for collecting atmospheric M/NPs and the analytical tools used for identification. The review identifies challenges and recommends further method development to support standardized and comparable future research.
ENVIRONMENT INTERNATIONAL
(2023)
Article
Chemistry, Multidisciplinary
Nikolaus Doppelhammer, Stefan Puttinger, Nick Pellens, Thomas Voglhuber-Brunnmaier, Karel Asselman, Bernhard Jakoby, Christine E. A. Kirschhock, Erwin K. Reichel
Summary: When solute molecules in a liquid evaporate at the surface, concentration gradients can lead to surface tension gradients and provoke fluid convection at the interface, a phenomenon known as the Marangoni effect. Minute quantities of ethanol in concentrated sodium hydroxide solution can induce pronounced and long-lasting Marangoni flow upon evaporation at room temperature. By employing particle image velocimetry and gravimetric analysis, the mean interfacial speed of the evaporating solution is shown to increase with the evaporation rate for ethanol concentrations below 0.5 mol%.
Review
Chemistry, Multidisciplinary
Karel Asselman, Christine Kirschhock, Eric Breynaert
Summary: Since the 1940s, researchers have been aiming to rationally design zeolites by controlling their synthesis to obtain desired properties. However, the fundamental processes of zeolite synthesis have remained largely unknown. This Account presents recent progress in crystallizing zeolites using hydrated silicate ionic liquids as synthesis media, allowing for the evaluation of the individual impacts of synthesis parameters on zeolite nucleation, growth, and phase selection. The relationship between the characteristics of the synthesis medium and the properties and structure of the crystalline product is elucidated.
ACCOUNTS OF CHEMICAL RESEARCH
(2023)
Article
Chemistry, Multidisciplinary
Hannelore Geerts-Claes, Gina Vanbutsele, Sreeprasanth Pulinthanathu Sree, Sambhu Radhakrishnan, C. Vinod Chandran, Eric Breynaert, Johan A. Martens, Sam Smet
Summary: RHO zeolites with different Si/Al ratios and particle morphologies were successfully synthesized by adding crown ether and adjusting the sodium content. The zeolites showed exceptional stability even at low Si/Al ratios, which can be attributed to the double eight-ring framework.
CRYSTAL GROWTH & DESIGN
(2023)
Article
Environmental Sciences
Manosij Ghosh, Katrijn Broothaerts, Steven Ronsmans, Ingrid Barcena Roig, Jef Scheepers, Mustafa Dikmen, Emily Rose Ciscato, Carolina Blanch, Michelle Plusquin, Unni C. Nygaard, Camilla Sandal Sejbaek, Karin S. Hougaard, Peter HM. Hoet
Summary: The article titled "Translation: Data Management Challenges and Solutions in the EXIMIOUS Project" discusses the difficulties faced by researchers in collecting and analyzing large volumes of data within collaborative projects. However, with the guidance and support from partner institutes, the researchers have been able to overcome these challenges and establish a data management framework that ensures data integrity, accessibility, and compliance with ethical and legal regulations.
ENVIRONMENTAL RESEARCH
(2023)
Article
Engineering, Chemical
Joris Claes, Bert Metten, Bert Brabants, Mumin Enis Leblebici, Simon Kuhn, Leen C. J. Thomassen
Summary: The influence of oscillatory parameters on particle behavior in heterogeneous solid-liquid reactions in flow was investigated. It was found that an oscillatory Reynolds number larger than 3000 narrowed the residence time distribution (RTD) and limited the velocity difference between particles. However, the amplitude and frequency of the pulsator had no direct effect on particle velocity under the studied conditions.
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
(2023)
Review
Medicine, Legal
Jia-You Gong, Manosij Ghosh, Peter HM. Hoet
Summary: Electronic cigarette use is associated with metal exposure and adverse health effects such as cytotoxicity, oxidative stress, genotoxicity, and pro-inflammatory responses. Epidemiological studies indicate elevated metal burden in e-cigarette users, but more detailed data and information are needed to uncover the metal-related hazards of e-cigarettes.
REGULATORY TOXICOLOGY AND PHARMACOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Sambhu Radhakrishnan, Charlotte Lejaegere, Karel Duerinckx, Wei-Shang Lo, Alysson F. F. Morais, Dirk Dom, C. Vinod Chandran, Ive Hermans, Johan A. A. Martens, Eric Breynaert
Summary: During the liquid phase adsorption of C-1-C-5 primary alcohols on high silica MFI zeolites, the concentration of adsorbed molecules exceeds the traditional adsorption sites. This additional adsorption is driven by hydrogen bonding between the alcohol function and the zeolite siloxane bridges, while chemi- and physi-sorption on traditional sites also occur simultaneously.
MATERIALS HORIZONS
(2023)
Proceedings Paper
Materials Science, Characterization & Testing
Nikolaus Doppelhammer, Dries Vandenabeele, Karel Asselman, Eric Breynaert, Bernhard Jakoby, Christine E. A. Kirschhock
Summary: Studying the kinetics of crystal formation is crucial for understanding the self-assembly of complex materials. This study proposes a differential impedance measurement method to accurately track the in situ crystallization of zeolites, overcoming the limitations of classical electrode-based impedance spectroscopy.
2023 INTERNATIONAL WORKSHOP ON IMPEDANCE SPECTROSCOPY, IWIS
(2023)
Article
Chemistry, Physical
Geert Watson, Nithin B. Kummamuru, Sammy W. Verbruggen, Patrice Perreault, Maarten Houlleberghs, Johan Martens, Eric Breynaert, Pascal van der Voort
Summary: This study explores the use of hydrophobic periodic organosilica nanoparticles for hydrogen storage as clathrate hydrates. The surface decoration with promoter agents enhances the formation and growth kinetics of clathrate hydrates, resulting in an increase in hydrogen storage capacity. These findings are of significant importance for the development of hydrogen clathrates in industrial applications.
JOURNAL OF MATERIALS CHEMISTRY A
(2023)
Article
Multidisciplinary Sciences
Nirosha Ganesan, Steven Ronsmans, Peter Hoet
Summary: The detection of antigen specific lymphocyte responses plays a vital role in diagnosing various diseases. This study evaluated the suitability of the Be-specific LPT and CFSE assay in detecting beryllium sensitivity in sarcoidosis patients with suspected beryllium exposure. The results showed that both LPT and CFSE assay are suitable for detecting beryllium sensitivity in sarcoidosis patients, but CFSE assay has an advantage in identifying the relevant proliferating lymphocyte populations.