期刊
NANOSCALE
卷 6, 期 16, 页码 9599-9603出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4nr02711f
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资金
- Fondazione Banco di Sardegna [186/2011.0484, 2013.1308]
- University of Sassari (Italy)
- Sardinia Region [CRP-59720]
- Gianfranco del Prete, doctor and scientist. The future: medicine, biology and nanotechnology Award
- European Union [HEALTH-2007-201587]
- Sardinia Region
Spaceflights lead to dysregulation of the immune cell functionality affecting the expression of activation markers and cytokine production. Short oxidized multi-walled carbon nanotubes functionalized by 1,3-dipolar cycloaddition have been reported to activate immune cells. In this Communication we have performed surface marker assays and multiplex ELISA on primary monocytes and T cells under microgravity. We have discovered that carbon nanotubes, through their immunostimulatory properties, are able to fight spaceflight immune system dysregulations.
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