4.8 Article

A single-molecule force spectroscopy study of the interactions between lectins and carbohydrates on cancer and normal cells

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NANOSCALE
卷 5, 期 8, 页码 3226-3229

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ROYAL SOC CHEMISTRY
DOI: 10.1039/c3nr00553d

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  1. MOST [2011CB933600]
  2. NSFC [21073181, 20975098]
  3. 100 talent Program of CAS

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The interaction forces between carbohydrates and lectins were investigated by single-molecule force spectroscopy on both cancer and normal cells. The binding kinetics was also studied, which shows that the carbohydrate-lectin complex on cancer cells is less stable than that on normal cells.

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