Review
Pharmacology & Pharmacy
Dan Zhang, Lin Liu, Jian Wang, Hong Zhang, Zhuo Zhang, Gang Xing, Xuan Wang, Minghua Liu
Summary: Nanoparticles based on PLGA and PEG-PLGA have been extensively studied for drug delivery in cancer treatment. These nanoparticles can encapsulate and release various drugs, and their surface can be modified with ligands for active tumor targeting. This review provides an overview of the synthesis, application, and recent advances of PEG-PLGA nanoparticles in cancer treatment.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Polymer Science
Wei Chen, Peng Liu
Summary: The study focused on the synthesis of PEGylated dendritic polyurethane for ultrasound-triggered localized drug delivery. The nanomedicine showed excellent intracellular drug release performance in simulated tumor environment and enhanced tumor growth inhibition on HepG2 cells compared to free DOX.
Article
Polymer Science
Weinan Gu, Ranran Fan, Jingnan Quan, Yi Cheng, Shanshan Wang, Hui Zhang, Aiping Zheng, Shenghan Song
Summary: In this research, a thermosensitive polymer was used as a drug delivery system to form a drug-gel depot inside the resection cavity after surgical excision, effectively suppressing glioblastoma recurrence. The study successfully adjusted the gelation point by blending polymers and demonstrated excellent therapeutic efficacy in in vitro and in vivo experiments.
Review
Chemistry, Multidisciplinary
Xianbin Ma, Shu-Jin Li, Yuantong Liu, Tian Zhang, Peng Xue, Yuejun Kang, Zhi-Jun Sun, Zhigang Xu
Summary: Nanogels, as a versatile drug delivery system, play a crucial role in cancer immunotherapy, offering advantages such as enhanced drug bioavailability and reduced immune-related adverse events.
CHEMICAL SOCIETY REVIEWS
(2022)
Article
Chemistry, Multidisciplinary
Xiangang Huang, Gongwei Wu, Chuang Liu, Xianwu Hua, Zhongmin Tang, Yufen Xiao, Wei Chen, Jun Zhou, Na Kong, Peng Huang, Jinjun Shi, Wei Tao
Summary: This study presents a novel approach using an intercalation-driven siRNA nanogels (NG) as a delivery vehicle, which demonstrates good stability and efficient intracellular delivery for cancer therapy.
Article
Pharmacology & Pharmacy
Soumaye Amirsaadat, Davoud Jafari-Gharabaghlou, Sepideh Alijani, Hanieh Mousazadeh, Mehdi Dadashpour, Nosratollah Zarghami
Summary: The study demonstrates that MET/SIL-loaded PLGA-PEG NPs exhibit synergistic cytotoxic effects against breast cancer cells, significantly altering the expression levels of related genes, and showing better therapeutic effects compared to single drug-loaded NPs and the free drug combination.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2021)
Article
Polymer Science
Neda Rostami, Farzaneh Faridghiasi, Aida Ghebleh, Hadi Noei, Meisam Samadzadeh, Mohammad Mahmoudi Gomari, Alireza Tajiki, Majid Abdouss, Alireza Aminoroaya, Manisha Kumari, Reza Heidari, Vladimir N. Uversky, Bryan R. Smith
Summary: In this study, copolymers PLA-PEG-PLA and PEG-PLA-PEG were synthesized and compared for their delivery capacity of curcumin to MCF-7 breast cancer cells. The results showed that PLA-PEG-PLA had stronger interaction with the cell membrane and lower free energy, making it a better carrier for cell membrane penetration.
Article
Multidisciplinary Sciences
Shima Shahrad, Mohammad Rajabi, Hamidreza Javadi, Ali Akbar Karimi Zarchi, Mohammad Hasan Darvishi
Summary: MUC1 aptamer-functionalized PLA-PEG nanocarriers were prepared at various w/w ratios and evaluated for their physiochemical properties, drug release kinetics, cytotoxicity, and antitumor activity. Targeted nanocarriers at a w/w ratio of 10:1 demonstrated significantly higher apoptosis rates in MUC1-overexpressing cancer cells compared to non-targeted and free drug forms, suggesting their potential as a promising drug delivery system for targeted therapy.
SCIENTIFIC REPORTS
(2022)
Article
Instruments & Instrumentation
Dasharath Chaudhari, Kaushik Kuche, Vivek Yadav, Rohan Ghadi, Tushar Date, Nallamothu Bhargavi, Sanyog Jain
Summary: In this study, PTX-loaded adenosine-conjugated PLGA nanoparticles were developed for treating TNBC. The nanoparticles showed a small size, high entrapment efficiency, and release at a lower pH. They also exhibited lower hemolysis and improved cellular uptake and anti-TNBC activity compared to free PTX. The nanoparticles had a favorable pharmacokinetic profile and reduced tumor burden without causing significant changes in kidney and liver function biomarkers or histological alterations. Overall, the optimized nanoparticles showed biocompatibility and enhanced anti-TNBC activity.
DRUG DELIVERY AND TRANSLATIONAL RESEARCH
(2023)
Article
Biotechnology & Applied Microbiology
Kristen M. Manto, Prem Kumar Govindappa, Brandon Martinazzi, Aijie Han, John P. Hegarty, Zachary Koroneos, M. A. Hassan Talukder, John C. Elfar
Summary: This study synthesized an EPO-PLGA-PEG block copolymer formulation and found that it could release stable EPO and significantly improve functional recovery and neurovascular regeneration after nerve injury.
JOURNAL OF NANOBIOTECHNOLOGY
(2022)
Review
Chemistry, Multidisciplinary
Amaal Abdulraqeb Ali, Amani Al-Othman, Mohammad H. Al-Sayah
Summary: Hybrid nanogels are emerging as novel and multifunctional cancer therapeutic strategies, with the potential to possess cytotoxic effects, carry drugs/enzymes, improve imaging, and target tumor cells. Despite their promising abilities, their clinical application is limited and further research is needed. Factors affecting their future include lack of hemocompatibility studies, toxicological evaluations, and information on tumor heterogeneity and interaction with physiological fluids.
JOURNAL OF CONTROLLED RELEASE
(2022)
Review
Pharmacology & Pharmacy
Yanhong Liu, Linjiao Chen, Qingyang Shi, Qing Zhao, Hongshuang Ma
Summary: Tumor microenvironment-responsive polypeptide nanogels have excellent biocompatibility and degradability, and can be used for selective delivery of antitumor drugs. These nanogels can release drugs in response to stimuli from tumor tissues or cells, reducing side effects and improving efficacy.
FRONTIERS IN PHARMACOLOGY
(2021)
Article
Pharmacology & Pharmacy
Seyedeh Nesa Rezaeian Shiadeh, Farzin Hadizadeh, Elham Khodaverdi, Mahmoud Gorji Valokola, Saleh Rakhshani, Hossein Kamali, Ali Nokhodchi
Summary: Novel drug delivery systems based on in situ forming gel (ISFG) (PLGA-PEG-PLGA) and in situ forming implant (ISFI) (PLGA) were developed for one-month risperidone delivery in this study. Results indicated sustained release for about one month with the formulation containing 50% PLGA-PEG-PLGA triblock. ISFG showed higher cell viability than ISFI due to the gradual release of NMP. The optimized PLGA-PEG-PLGA exhibited consistent serum levels in vitro and in vivo through 30 days.
Article
Engineering, Biomedical
Farzaneh Sadeghzadeh, Atefeh Sadat Ziaratnia, Masoud Homayouni Tabrizi, Ghazal Hosseini Torshizi, Maitham Alhajamee, Davoud Khademi
Summary: This study aimed to develop a PLGA-based nanosystem modified with PEG, chitosan, and folic acid for the delivery of colchicine to cancer cells. The fabricated nanosystem showed antioxidant effects and induced apoptosis in HT-29 cancer cells. The use of PPCF-NPs system for colchicine delivery can selectively target cancer cells and induce apoptosis.
JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION
(2023)
Review
Polymer Science
Bibi Noorheen Haleema Mooneerah Neerooa, Li-Ting Ooi, Kamyar Shameli, Nuraina Anisa Dahlan, Jahid M. M. Islam, Janarthanan Pushpamalar, Sin-Yeang Teow
Summary: Nanoparticles and nanogels, as rising fields in cancer therapy, offer high flexibility, eco-friendly properties, and variable physicochemical characteristics. Polymers enhance the bioactivity of nanomaterials and contribute to the unique properties of nanodrugs through diverse synthesis methods.
Article
Chemistry, Multidisciplinary
Keda Chen, Xiaoxin Wu, Qingjing Wang, Ying Wang, Haiyan Zhang, Shuai Zhao, Chaonan Li, Zhiwen Hu, Zhimou Yang, Lanjuan Li
Summary: Repeated waves of H7N9 influenza virus have caused severe influenza in humans since 2013, with a high mortality rate. To prevent possible pandemics, the development of highly effective vaccines against H7N9 is crucial. In this study, a simple method using a peptide hydrogel adjuvant was reported to prepare the H7N9 vaccine, which showed better preventive effects against H7N9 infection compared to traditional adjuvant vaccines. The study also revealed higher antibody responses and variations in cytokine expression as potential mechanisms for the increased protective effects of the hydrogel adjuvant vaccine.
CHINESE CHEMICAL LETTERS
(2023)
Article
Chemistry, Multidisciplinary
Xuejiao Yang, Honglei Lu, Nan Kong, Huaimin Wang
Summary: The self-assembly of peptides is important in various fields such as optics, catalysis, medicine, and disease treatment. Peptide-based materials have shown great potential for cancer therapy and disease imaging due to their biocompatibility, tunability, and ease of functionality. Peptides can self-assemble into nanostructures in vivo triggered by endogenous stimuli, allowing for chemical reactions and achieving desired biological functions in the tumor microenvironment. This concept introduces the use of endogenous triggers to construct functional nanostructures in vivo and their corresponding biological applications.
CHEMISTRY-A EUROPEAN JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Yinghao Ding, Debin Zheng, Limin Xie, Xiangyang Zhang, Zhenghao Zhang, Ling Wang, Zhi-Wen Hu, Zhimou Yang
Summary: An enzyme-instructed peptide self-assembly (EISA) strategy is used to selectively modify cancer cell membranes, and different phosphorylation patterns in phosphopeptides targeting EGFR can impact their self-assembly abilities and binding affinity for EGFR. The phosphorylated peptide pY1 shows the highest capability for preorganization and the fastest dephosphorylation in the presence of alkaline phosphatase (ALP), making it the most effective at constructing stable peptide assemblies on cancer cell membranes. Additionally, peptide-protein and peptide-peptide co-assembly strategies are employed to apply antigens to cancer cell membranes, offering a potential technique for cancer immunotherapy.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Materials Science, Multidisciplinary
Tengyan Xu, Huihui Ren, Yu Fang, Kun Liang, Hongyue Zhang, Dingwei Li, Yitong Chen, Bowen Zhu, Huaimin Wang
Summary: This study presents the first example of a peptidic hydrogel gated bio-FET by surface assisted self-assembly for label-free and real-time monitoring of glucose. The boric acid-containing peptide forms a hydrogel layer on the surface of In2O3, which interacts with glucose reversibly and influences the semiconductor's conductivity. The results demonstrate the superiority of hydrogel gated bio-FET for real-time monitoring of glucose in complex environments and its potential as a wearable device. This work illustrates a simple and fundamental strategy for integrating peptidic hydrogel with bio-FET for the real-time detection of analytes.
APPLIED MATERIALS TODAY
(2023)
Article
Engineering, Biomedical
Hongwei Wu, Yuna Shang, Wei Sun, Xinyi Ouyang, Wenyan Zhou, Jieji Lu, Shuhui Yang, Wei Wei, Xudong Yao, Xiaozhao Wang, Xianzhu Zhang, Yishan Chen, Qiulin He, Zhimou Yang, Hongwei Ouyang
Summary: This study developed a strategy to enhance integration of the gap region following mosaicplasty by applying BSN-GelMA hydrogel. The results showed that BSN-GelMA achieved seamless osteochondral healing in the gap region, with improved cartilage repair scores, glycosaminoglycan content, subchondral bone volume, and collagen II expression. This study provides a powerful approach to improve gap integration after autologous mosaicplasty and offers a promising bioactive material for cell-free tissue regeneration.
BIOACTIVE MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Weidong Wu, Shuaijun Jia, Hailiang Xu, Ziheng Gao, Zhiyuan Wang, Botao Lu, Yixiang Ai, Youjun Liu, Renfeng Liu, Tong Yang, Rongjin Luo, Chunping Hu, Lingbo Kong, Dageng Huang, Liang Yan, Zhimou Yang, Lei Zhu, Dingjun Hao
Summary: A strategy of using PDGF-MP hydrogel microspheres instead of bulk hydrogels can enhance the efficiency of PDGF-MP in activating its receptor, thus improving the therapeutic ability of neural stem cells (NSCs) in treating spinal cord injuries (SCI). In vitro experiments showed that PDGF-MP hydrogel microspheres maintained the proliferation and inhibited the apoptosis of NSCs in the presence of myelin extracts. In vivo experiments demonstrated that PDGF-MP hydrogel microspheres inhibited inflammatory cell infiltration and cell apoptosis, and promoted axonal regeneration, synapse formation, and angiogenesis in SCI rats.
Article
Chemistry, Multidisciplinary
Hongyue Zhang, Xuejiao Yang, Juan Liang, Kaihua Chen, Huaimin Wang
Summary: Guanosine-based hydrogels have limitations due to the necessity of sugar in hydrogel formation. A novel G-quadruplexes-based hydrogel was developed by using guanine and peptide epitope in the presence of metal cations. Metal cations can control the gelation time, nanofiber diameter, anisotropic property, and mechanical property of the hydrogel. This work demonstrates a simple way to develop soft materials by modulating the properties of nucleopeptide hydrogel.
CHINESE JOURNAL OF CHEMISTRY
(2023)
Article
Chemistry, Physical
Limin Xie, Yinghao Ding, Xiangyang Zhang, Zhenghao Zhang, Sheng Zeng, Ling Wang, Zhimou Yang, Qian Liu, Zhi-Wen Hu
Summary: The researchers constructed a multifunctional drug-loaded peptide nanomedicine (Comp. 4) for ICD-based cancer therapy. Comp. 4 interferes with mitochondrial functions, targets the cell membrane and mitochondria, and forms peptide assemblies in the presence of ALP. Comp. 4 induces mitochondrial oxidative stress, provokes robust ICD responses, and successfully inhibits colon cancer growth by eliciting a systemic ICD-based antitumor immunity.
Article
Chemistry, Multidisciplinary
Yumiao Chen, Wei Li, Zhongqiu Wang, Yingying Yu, Jie Li, Yinghao Ding, Zhiwen Hu, Qian Liu, Zhimou Yang, Jie Gao
Summary: This study introduces a novel cancer immunotherapy tool, Supra-BiCE, that enhances the binding of immune cells to tumor cells by transforming nanoribbons into nanofibrils, leading to the accumulation and activation of immune cells within tumor regions.
ADVANCED MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Xiangyang Zhang, Yinghao Ding, Zhenghao Zhang, Yiping Ma, Xuan Sun, Ling Wang, Zhimou Yang, Zhi-Wen Hu
Summary: Manipulating cancer cell death through precise control of reactive oxygen species (ROS) is a promising strategy for treating malignant tumors. However, generating active ROS with spatial precision and regulating their biological outcomes is challenging. In this study, we successfully generated short-lived and lipid-reactive hydroxyl radicals ((OH)-O-·) adjacent to cancer cell membranes, leading to lipid peroxidation and ferroptosis. By using a phosphorylated self-assembling precursor, we selectively produced membrane-bound nanofibers and enriched ferrocene moieties on cancer cell membranes, resulting in the conversion of tumoral H2O2 to active (OH)-O-· through Fenton-like reactions. Our strategy effectively prevented tumor progression with good cellular selectivity and acceptable biocompatibility through intratumoral administration.
Article
Chemistry, Multidisciplinary
Zhuhong Zhang, Shengjun Peng, Tengyan Xu, Jia Liu, Laien Zhao, Hui Xu, Wen Zhang, Yuanying Zhu, Zhimou Yang
Summary: In this study, a self-assembling peptide GFFYE was designed and synthesized to transform rhein, a hydrophobic compound, into a sustained-release therapeutic agent. Rhein-based nanofibers were constructed for the treatment of retinal ischemia-reperfusion (RIR) injury, and they showed significant improvement in oxidative stress and inflammation. Moreover, the nanofibers promoted the transition of macrophages from pro-inflammatory to anti-inflammatory type.
Article
Chemistry, Multidisciplinary
Zhongyan Wang, Yuna Shang, Hongjing Luo, Cuihong Yang, Zhimou Yang, Chunhua Ren, Jianfeng Liu
Summary: This study presents a novel strategy of achieving higher hierarchical structures through cooperative self-assembly of hydrophobic tripeptides with reverse sequences, showing a low-to-high hierarchical structure transformation. The cooperation between different sequences also allows different morphological transitions, promoting a more compact molecular arrangement by creating more hydrogen bond interactions and in-register π-π stacking in the anti-parallel β-sheet conformation. This work provides a handy approach for controlled hierarchical assembly and the development of various functional bionanomaterials.
Review
Chemistry, Multidisciplinary
Xiangyang Zhang, Junxia Wang, Ying Zhang, Zhimou Yang, Jie Gao, Zhen Gu
Summary: Living organisms fabricate biomacromolecules such as DNA, RNA, and proteins through self-assembly, and understanding this process has led to exploration in synthesizing biomaterials within living organisms. In recent decades, these in vivo synthesized biomaterials have been extensively applied in cell-fate manipulation, disease theranostics, bioanalysis, cellular surface engineering, and tissue regeneration.
CHEMICAL SOCIETY REVIEWS
(2023)
Article
Materials Science, Biomaterials
Yiming Zhang, Zhiwen Hu, Xinxin Li, Yinghao Ding, Zhenghao Zhang, Xiangyang Zhang, Wenting Zheng, Zhimou Yang
Summary: The amino acid sequence of the peptide determines the adjuvant potency of Gel-gffy. The position and number of aromatic amino acids play a crucial role in the immunostimulatory activity of Gel-gffy. These findings provide valuable insights into designing peptide hydrogels as vaccine adjuvants.
BIOMATERIALS SCIENCE
(2022)
Article
Chemistry, Multidisciplinary
Huyeon Choi, Gaeun Park, Eunhye Shin, Seon Woo Shin, Batakrishna Jana, Seongeon Jin, Sangpil Kim, Huaimin Wang, Sang Kyu Kwak, Bing Xu, Ja-Hyoung Ryu
Summary: Mitochondria-targeting nucleopeptide can sequester ATP by self-assembling, leading to apoptosis of cancer cells.
Article
Chemistry, Multidisciplinary
Laetitia Bardet, Herve Roussel, Stefano Saroglia, Masoud Akbari, David Munoz-Rojas, Carmen Jimenez, Aurore Denneulin, Daniel Bellet
Summary: The thermal instability of silver nanowires leads to increased electrical resistance in AgNW networks. Understanding the relationship between structural and electrical properties of AgNW networks is crucial for their integration as transparent electrodes in flexible optoelectronics. In situ X-ray diffraction measurements were used to study the crystallographic evolution of Ag-specific Bragg peaks during thermal ramping, revealing differences in thermal and structural transitions between bare and SnO2-coated AgNW networks.
Article
Chemistry, Multidisciplinary
Nathalia Cancino-Fuentes, Arnau Manasanch, Joana Covelo, Alex Suarez-Perez, Enrique Fernandez, Stratis Matsoukis, Christoph Guger, Xavi Illa, Anton Guimera-Brunet, Maria V. Sanchez-Vives
Summary: This study provides a comprehensive characterization of graphene-based solution-gated field-effect transistors (gSGFETs) for brain recordings, highlighting their potential clinical applications.
Article
Chemistry, Multidisciplinary
Sikandar Aftab, Hailiang Liu, Dhanasekaran Vikraman, Sajjad Hussain, Jungwon Kang, Abdullah A. Al-Kahtani
Summary: This study examines the effects of hybrid nanoparticles made of NiO@rGO and NiO@CNT on the active layers of polymer solar cells and X-ray photodetectors. The findings show that these hybrid nanoparticles can enhance the charge carrier capacities and exciton dissociation properties of the active layers. Among the tested configurations, the NiO@CNT device demonstrates superior performance in converting sunlight into electricity, and achieves the best sensitivity for X-ray detection.
Article
Chemistry, Multidisciplinary
Hyo Jung Shin, Seung Gyu Choi, Fengrui Qu, Min-Hee Yi, Choong-Hyun Lee, Sang Ryong Kim, Hyeong-Geug Kim, Jaewon Beom, Yoonyoung Yi, Do Kyung Kim, Eun-Hye Joe, Hee-Jung Song, Yonghyun Kim, Dong Woon Kim
Summary: This study investigates the role of SOX9 in reactive astrocytes following ischemic brain damage using a PLGA nanoparticle plasmid delivery system. The results demonstrate that PLGA nanoparticles can reduce ischemia-induced neurological deficits and infarct volume, providing a potential opportunity for stroke treatment.
Article
Chemistry, Multidisciplinary
Anurag Chaudhury, Koushik Debnath, Nikhil R. Jana, Jaydeep K. Basu
Summary: The study investigates the interaction between nanoparticles and cell membranes, and identifies key parameters, including charge, crowding, and membrane fluidity, that determine the adsorbed concentration and unbinding transition of nanoparticles.
Article
Chemistry, Multidisciplinary
Sina Sadeghi, Fazel Bateni, Taekhoon Kim, Dae Yong Son, Jeffrey A. Bennett, Negin Orouji, Venkat S. Punati, Christine Stark, Teagan D. Cerra, Rami Awad, Fernando Delgado-Licona, Jinge Xu, Nikolai Mukhin, Hannah Dickerson, Kristofer G. Reyes, Milad Abolhasani
Summary: In this study, an autonomous approach for the development of lead-free metal halide perovskite nanocrystals is presented, which integrates a modular microfluidic platform with machine learning-assisted synthesis modeling. This approach enables rapid and optimized synthesis of copper-based lead-free nanocrystals.
Article
Chemistry, Multidisciplinary
Zahir Abbas, Nissar Hussain, Surender Kumar, Shaikh M. Mobin
Summary: The rational construction of free-standing and flexible electrodes for electrochemical energy storage devices is an emerging research focus. In this study, a redox-active metal-organic framework (MOF) was prepared on carbon nanofibers using an in situ approach, resulting in a flexible electrode with high redox-active behavior and unique properties such as high flexibility and lightweight. The prepared electrode showed excellent cyclic retention and rate capability in supercapacitor applications. Additionally, it could be used as a freestanding electrode in flexible devices at different bending angles.
Article
Chemistry, Multidisciplinary
Lishan Zhang, Xiaoting Zhang, Hui Ran, Ze Chen, Yicheng Ye, Jiamiao Jiang, Ziwei Hu, Miral Azechi, Fei Peng, Hao Tian, Zhili Xu, Yingfeng Tu
Summary: Photodynamic therapy (PDT) is a promising local treatment modality in cancer therapy, but its therapeutic efficacy is restricted by ineffective delivery of photosensitizers and tumor hypoxia. In this study, a phototactic Chlorella-based near-infrared (NIR) driven green affording-oxygen microrobot system was developed for enhanced PDT. The system exhibited desirable phototaxis and continuous oxygen generation, leading to the inhibition of tumor growth in mice. This study demonstrates the potential of using a light-driven green affording-oxygen microrobot to enhance photodynamic therapy.
Article
Chemistry, Multidisciplinary
Yujin Li, Jing Xu, Xinqi Luo, Futing Wang, Zhong Dong, Ke-Jing Huang, Chengjie Hu, Mengyi Hou, Ren Cai
Summary: In this study, hollow heterostructured materials were constructed using an innovative template-engaged method as cathodes for zinc-ion batteries. The materials exhibited fast Zn2+ transport channels, improved electrical conductivity, and controlled volume expansion during cycling. The designed structure allowed for an admirable reversible capacity and high coulombic efficiency.
Article
Chemistry, Multidisciplinary
Paritosh Mahato, Shashi Shekhar, Rahul Yadav, Saptarshi Mukherjee
Summary: This study comprehensively elucidates the role of the core and electrostatic surface of metal nanoclusters in catalytic reduction reactions. The electrostatic surface dramatically modulates the reactivity of metal nanoclusters.
Article
Chemistry, Multidisciplinary
Pei Liu, Mengdi Liang, Zhengwei Liu, Haiyu Long, Han Cheng, Jiahe Su, Zhongbiao Tan, Xuewen He, Min Sun, Xiangqian Li, Shuai He
Summary: This study demonstrates a simple and environmentally-friendly method for the synthesis of zinc oxide nanozymes (ZnO NZs) using wasted hop extract (WHE). The WHE-ZnO NZs exhibit exceptional peroxidase-like activity and serve as effective catalysts for the oxidation of 3,3,5,5-tetramethylbenzidine (TMB) in the presence of hydrogen peroxide (H2O2). In addition, a straightforward colorimetric technique for detecting both H2O2 and glucose was developed using the WHE-ZnO NZs as peroxidase-like catalysts.
Article
Chemistry, Multidisciplinary
Hyunkyu Oh, Young Jun Lee, Eun Ji Kim, Jinseok Park, Hee-Eun Kim, Hyunsoo Lee, Hyunjoo Lee, Bumjoon J. Kim
Summary: Mesoporous carbon particles have unique structural properties that make them suitable as support materials for catalytic applications. This study investigates the impact of channel nanostructures on the catalytic activity of porous carbon particles (PCPs) by fabricating PCPs with controlled channel exposure on the carbon surface. The results show that PCPs with highly open channel nanostructures exhibit significantly higher catalytic activity compared to those with closed channel nanostructures.
Article
Chemistry, Multidisciplinary
Yunjie Lu, Zhaohui Li, Zewei Li, Shihao Zhou, Ning Zhang, Jianming Zhang, Lu Zong
Summary: A tough, long-lasting adhesive and highly conductive nanocomposite hydrogel (PACPH) was fabricated via the synergy of interfacial entanglement and adhesion group densification. PACPH possesses excellent mechanical properties, interfacial adhesion strength, and conductivity, making it a promising material for long-term monitoring of human activities and electrocardiogram signals.
Article
Chemistry, Multidisciplinary
Zichao Wei, Audrey Vandergriff, Chung-Hao Liu, Maham Liaqat, Mu-Ping Nieh, Yu Lei, Jie He
Summary: We have developed a simple method to prepare polymer-grafted plasmonic metal nanoparticles with pH-responsive surface-enhanced Raman scattering. By using pH-responsive polymers as ligands, the aggregation of nanoparticles can be controlled, leading to enhanced SERS. The pH-responsive polymer-grafted nanoparticles show high reproducibility and sensitivity in solution, providing a novel approach for SERS without the need for sample pre-concentration.
Article
Chemistry, Multidisciplinary
Melis Ozge Alas Colak, Ahmet Gungor, Merve Buldu Akturk, Emre Erdem, Rukan Genc
Summary: This research investigates the effect of functionalizing carbon dots with hydroxyl polymers on their performance as electrode materials in a supercapacitor. The results show that the functionalized carbon dots exhibit excellent electrochemical performance and improved stability.
