Article
Chemistry, Analytical
Jia Liu, Hugues Lambert, Yong-Wei Zhang, Tung-Chun Lee
Summary: A novel approach using electrochemistry was reported for estimating the binding constants of supramolecular complexes, achieving high precision and practical accuracy in a short measurement time. The study uncovered a linear correlation between the reduction potential of the ternary complexes and their binding constants, allowing for potential applications for sparsely soluble second guests.
ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Saurav Das, Tanushree Das, Priyam Das, Debapratim Das
Summary: Nature has developed a self-regulatory feedback mechanism that maintains an optimal internal cellular environment. Researchers have designed a pH responsive supramolecular peptide amphiphile to mimic the inhibitory behavior of certain enzymes. The resulting nanozymes showed tunable lifetimes and efficient reproducibility across multiple pH cycles.
Article
Chemistry, Multidisciplinary
Wei Zhang, Yang Luo, Jie Zhao, Chao Zhang, Xin-Long Ni, Zhu Tao, Xin Xiao
Summary: In this study, a linear supramolecular polymer with controllable features was constructed based on twisted cucurbit[14]uril and cucurbit[8]uril using an effective self-sorting strategy. By inserting and π-π stacking, the polymerization and depolymerization of the supramolecular polymer were achieved. This strategy provides a new approach for the design of supramolecular polymer materials and the application of twisted cucurbit[14]uril in supramolecular chemistry.
CHINESE CHEMICAL LETTERS
(2022)
Article
Chemistry, Multidisciplinary
De-Ao Xu, Qing-Yang Zhou, Xianyin Dai, Xin-Kun Ma, Ying-Ming Zhang, Xiufang Xu, Yu Liu
Summary: A phosphorescent supramolecular foldamer has been successfully constructed through the 1:1 host-guest complexation with cucurbit[8]uril and 1,2-diaminocyclohexane-bridged 4-(4-bromophenyl)-pyridinium salt. The foldamer exhibits green phosphorescence in aqueous solution and shows rapid and sensitive responsiveness to different antibiotics.
CHINESE CHEMICAL LETTERS
(2022)
Article
Chemistry, Multidisciplinary
Xueyan Zhang, Shaolong Qi, Dahai Liu, Jianshi Du, Jingji Jin
Summary: Nanomedicines are crucial in cancer therapy, but the unsatisfactory efficacy and side effects caused by indiscriminate drug release limit their clinical applications. Utilizing a supramolecular strategy, researchers have designed targeted nanomedicines that enhance the efficiency of drugs, showing potential in precise cancer treatment and the development of sophisticated drug delivery systems.
FRONTIERS IN CHEMISTRY
(2022)
Article
Chemistry, Physical
Nanhang Zhu, Yujia Zhang, Jia Cheng, Yanchao Mao, Ke Kang, Guohao Li, Qiangying Yi, Yao Wu
Summary: Researchers have proposed an 1-ADA responsive immuno-affinitive supramolecular magnetic nanoparticle (ISM-NPs) system for efficient capture and release of sEVs. This system shows high capture efficiency and good release performance, providing potential applications in biomarker enrichment.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2022)
Article
Chemistry, Applied
Hong-Guang Fu, Jinmao You
Summary: Multicolor emission materials responsive to visible light stimuli have great potential in biomedical engineering and materials science. In this study, a dual-visible-light responsive quaternary supramolecular assembly with tunable multicolor fluorescence outputs was constructed. The assembly exhibited three different photoluminescent colors, yellow, white, and blue, by varying the irradiation time, and showed promising applications in photocontrolled cell imaging and photoerasable fluorescent ink.
Article
Chemistry, Multidisciplinary
Miriam Colaco, Patricia Maximo, A. Jorge Parola, Nuno Basilio
Summary: The study focuses on the kinetics of a water-soluble host-guest system based on cucurbit[8]uril and two DTE photoswitches, demonstrating a method to control the binding kinetics in supramolecular systems using external stimuli. By modifying the structure of the DTE guest molecule, it is possible to significantly slow down the formation/dissociation rates of pseudorotaxane structures, leading to the emergence of a competitive metastable product with important impact on the overall binding kinetics. Additionally, the dissociation kinetics of the host-guest system can be controlled by approximately 100-fold by switching between closed and open DTE isomers.
CHEMISTRY-A EUROPEAN JOURNAL
(2021)
Article
Chemistry, Applied
Chen Xu, Xiaohan Lin, Xiang Ma
Summary: Highly emissive fluorescent dyes are important in fluorescence imaging technology and fluorescence spectrometry, but the insoluble nature of most organic dyes in water has limited their application. This study presents a one-step supramolecular strategy to enhance the aqueous quantum yields of fluorescent dyes by binding them with cucurbit[8]uril. The resulting assembly showed a significant increase in quantum yields from 3.9% to 46.9% and formed spherical supramolecular nanoparticles. The mechanism of fluorescence enhancement and self-assembly of the dye were also investigated.
Article
Biotechnology & Applied Microbiology
Han Wu, Zuobing Chen, Shaolong Qi, Bing Bai, Jiajun Ye, Dan Wu, Jie Shen, Fei Kang, Guocan Yu
Summary: The study confirmed the stability of host-guest complexation between CB[8] and 4,4'-bipyridinium and napththyl guest in physiological environment, leading to the successful construction of a supramolecular nanomedicine based on this molecular recognition with promising potentials in anticancer therapy.
JOURNAL OF NANOBIOTECHNOLOGY
(2021)
Article
Biochemical Research Methods
Paula Novo, Marcos D. Garcia, Carlos Peinador, Elena Pazos
Summary: Many cellular processes in living organisms are regulated by complex regulatory networks involving relatively few proteins that switch between different assemblies to perform their functions. This study demonstrates that the conjugation of a specific scaffold to a transcription factor can control its dimerization through a supramolecular complex, allowing for reversible binding to DNA target in response to external stimuli.
BIOCONJUGATE CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Yawen Li, Qingfang Li, Xiaran Miao, Chunyan Qin, Dake Chu, Liping Cao
Summary: Achiral supramolecular organic framework (SOF-1) can exhibit adaptive chirality induced by specific compounds in water, leading to mirror-image circular dichroism and circularly polarized luminescence. This adaptive chirality can be utilized for determining the enantiopurity of amino acids and distinguishing biological chiral macromolecules.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Chemistry, Multidisciplinary
Weijie Wu, Yinghao Xu, Shoujun Wang, Qingqing Pang, Simin Liu
Summary: Here we report the synthesis and characterization of two 2D layered metal-organic rotaxane frameworks (MORFs), WUST-1 and WUST-2, which are composed of a ternary host-guest complex based on cucurbit[8]uril (CB[8]) and an (E)-1-methyl-4-[4-(pyridin-4-yl)styryl] pyridinium (G1) ligand, along with different metal ions and auxiliary linkers. Both MORFs are stable in water, highly fluorescent, and can selectively sense nitrofurazone with low detection limits.
CHEMICAL COMMUNICATIONS
(2023)
Article
Biochemistry & Molecular Biology
Zhong-Zheng Gao, Lei Shen, Yu-Lu Hu, Ji-Fu Sun, Gang Wei, Hui Zhao
Summary: This study thoroughly investigated the use of naphthyl groups as building blocks for the self-assembly of supramolecular crystal networks in both aqueous solution and solid state. Experimental data showed that double guest molecules could reside within the cavity of Q[8], forming highly stable homoternary complexes NapA(2)@Q[8] and Nap1(2)@Q[8]. Strong hydrogen-bonding and π···π interactions played critical roles in the formation of 1D supramolecular chain, as well as 2D and 3D networks in solid state.
Article
Chemistry, Multidisciplinary
Zeng-Hui Zhang, Rui-Lian Lin, Xiang-Yun Yu, Li-Xia Chen, Zhu Tao, Xin Xiao, Gang Wei, Carl Redshaw, Jing-Xin Liu
Summary: The study showed that Q[8] can encapsulate l-valine, d-leucine, and d-methionine in aqueous solution. X-ray crystallography revealed the structural details of the inclusion complexes formed between Q[8] and the amino acids, with the deformation degree of the Q[8] host being related to the molecular size of the encapsulated guests.
Article
Nanoscience & Nanotechnology
Katarzyna Wybranska, Jan Paczesny, Katarzyna Serejko, Karolina Sura, Karolina Wlodyga, Igor Dziecielewski, Samuel T. Jones, Agnieszka Sliwa, Iwona Wybranska, Robert Holyst, Oren A. Scherman, Marcin Fialkowski
ACS APPLIED MATERIALS & INTERFACES
(2015)
Article
Chemistry, Analytical
Silvia Sonzini, Samuel T. Jones, Zarah Walsh, Oren A. Scherman
Article
Polymer Science
Paul E. Williams, Eric A. Appel, Samuel T. Jones, Jesus Del Barrio, Yang Lan, Oren A. Scherman
JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY
(2015)
Article
Polymer Science
Paul E. Williams, Samuel T. Jones, Zarah Walsh, Eric A. Appel, Enass K. Abo-Hamed, Oren A. Scherman
Article
Chemistry, Multidisciplinary
Samuel T. Jones, Zarah Walsh-Korb, Steven J. Barrow, Sarah L. Henderson, Jesus del Barrio, Oren A. Scherman
Article
Chemistry, Physical
Valeria Cagno, Patrizia Andreozzi, Marco D'Alicarnasso, Paulo Jacob Silva, Marie Mueller, Marie Galloux, Ronan Le Goffic, Samuel T. Jones, Marta Vallino, Jan Hodek, Jan Weber, Soumyo Sen, Emma-Rose Janecek, Ahmet Bekdemir, Barbara Sanavio, Chiara Martinelli, Manuela Donalisio, Marie-Anne Rameix Welti, Jean-Francois Eleouet, Yanxiao Han, Laurent Kaiser, Lela Vukovic, Caroline Tapparel, Petr Kral, Silke Krol, David Lembo, Francesco Stellacci
Article
Chemistry, Multidisciplinary
Samuel T. Jones, Richard W. Taylor, Ruben Esteban, Enass K. Abo-Hamed, Paul H. H. Bomans, Nico A. J. M. Sommerdijk, Javier Aizpurua, Jeremy J. Baumberg, Oren A. Scherman
Review
Virology
Valeria Cagno, Eirini D. Tseligka, Samuel T. Jones, Caroline Tapparel
Article
Multidisciplinary Sciences
Zekiye P. Guven, Paulo H. Jacob Silva, Zhi Luo, Urszula B. Cendrowska, Matteo Gasbarri, Samuel T. Jones, Francesco Stellacci
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS
(2019)
Article
Multidisciplinary Sciences
Samuel T. Jones, Valeria Cagno, Matej Janecek, Daniel Ortiz, Natalia Gasilova, Jocelyne Piret, Matteo Gasbarri, David A. Constant, Yanxiao Han, Lela Vukovi, Petr Kral, Laurent Kaiser, Song Huang, Samuel Constant, Karla Kirkegaard, Guy Boivin, Francesco Stellacci, Caroline Tapparel
Article
Materials Science, Multidisciplinary
Samuel T. Jones
JOURNAL OF MATERIALS SCIENCE
(2020)
Review
Multidisciplinary Sciences
Solen Monteill, Alexander J. Casson, Samuel T. Jones
Summary: Detecting viruses is crucial for health and economy, with a recent focus on faster and simpler electronic-based detection methods. Point-of-care sensors play a vital role in quick and quantitative virus detection, enabling rapid treatment. Electrical techniques such as voltammetry and field effect transistors are commonly used in electronic and electrochemical point-of-care sensors.
Article
Chemistry, Medicinal
Luke M. Jones, Elana H. Super, Lauren J. Batt, Matteo Gasbarri, Francesco Coppola, Lorraine M. Bhebhe, Benjamin T. Cheesman, Andrew M. Howe, Petr Kral, Roger Coulston, Samuel T. Jones
Summary: Viruses can cause diseases and mortality, but certain cucurbit[n]uril homologues, especially CB[7], have shown antiviral effects against a range of viruses. CB[7] acts as a supramolecular virucidal antiviral by interacting with viral surface proteins and the CB[n] cavity, rather than being internalized by cells or using a virustatic mechanism. This finding is significant for the development of future antiviral disinfectants.
ACS INFECTIOUS DISEASES
(2022)
Article
Chemistry, Multidisciplinary
Robert H. T. Bagley, Samuel T. Jones
Summary: Polymer nanoparticle hydrogels made of DNA and silica exhibit shear thinning, self-healing, sustained cargo release, and enzymatic degradation properties.
CHEMICAL COMMUNICATIONS
(2021)
Article
Chemistry, Multidisciplinary
Laetitia Bardet, Herve Roussel, Stefano Saroglia, Masoud Akbari, David Munoz-Rojas, Carmen Jimenez, Aurore Denneulin, Daniel Bellet
Summary: The thermal instability of silver nanowires leads to increased electrical resistance in AgNW networks. Understanding the relationship between structural and electrical properties of AgNW networks is crucial for their integration as transparent electrodes in flexible optoelectronics. In situ X-ray diffraction measurements were used to study the crystallographic evolution of Ag-specific Bragg peaks during thermal ramping, revealing differences in thermal and structural transitions between bare and SnO2-coated AgNW networks.
Article
Chemistry, Multidisciplinary
Nathalia Cancino-Fuentes, Arnau Manasanch, Joana Covelo, Alex Suarez-Perez, Enrique Fernandez, Stratis Matsoukis, Christoph Guger, Xavi Illa, Anton Guimera-Brunet, Maria V. Sanchez-Vives
Summary: This study provides a comprehensive characterization of graphene-based solution-gated field-effect transistors (gSGFETs) for brain recordings, highlighting their potential clinical applications.
Article
Chemistry, Multidisciplinary
Sikandar Aftab, Hailiang Liu, Dhanasekaran Vikraman, Sajjad Hussain, Jungwon Kang, Abdullah A. Al-Kahtani
Summary: This study examines the effects of hybrid nanoparticles made of NiO@rGO and NiO@CNT on the active layers of polymer solar cells and X-ray photodetectors. The findings show that these hybrid nanoparticles can enhance the charge carrier capacities and exciton dissociation properties of the active layers. Among the tested configurations, the NiO@CNT device demonstrates superior performance in converting sunlight into electricity, and achieves the best sensitivity for X-ray detection.
Article
Chemistry, Multidisciplinary
Hyo Jung Shin, Seung Gyu Choi, Fengrui Qu, Min-Hee Yi, Choong-Hyun Lee, Sang Ryong Kim, Hyeong-Geug Kim, Jaewon Beom, Yoonyoung Yi, Do Kyung Kim, Eun-Hye Joe, Hee-Jung Song, Yonghyun Kim, Dong Woon Kim
Summary: This study investigates the role of SOX9 in reactive astrocytes following ischemic brain damage using a PLGA nanoparticle plasmid delivery system. The results demonstrate that PLGA nanoparticles can reduce ischemia-induced neurological deficits and infarct volume, providing a potential opportunity for stroke treatment.
Article
Chemistry, Multidisciplinary
Anurag Chaudhury, Koushik Debnath, Nikhil R. Jana, Jaydeep K. Basu
Summary: The study investigates the interaction between nanoparticles and cell membranes, and identifies key parameters, including charge, crowding, and membrane fluidity, that determine the adsorbed concentration and unbinding transition of nanoparticles.
Article
Chemistry, Multidisciplinary
Sina Sadeghi, Fazel Bateni, Taekhoon Kim, Dae Yong Son, Jeffrey A. Bennett, Negin Orouji, Venkat S. Punati, Christine Stark, Teagan D. Cerra, Rami Awad, Fernando Delgado-Licona, Jinge Xu, Nikolai Mukhin, Hannah Dickerson, Kristofer G. Reyes, Milad Abolhasani
Summary: In this study, an autonomous approach for the development of lead-free metal halide perovskite nanocrystals is presented, which integrates a modular microfluidic platform with machine learning-assisted synthesis modeling. This approach enables rapid and optimized synthesis of copper-based lead-free nanocrystals.
Article
Chemistry, Multidisciplinary
Zahir Abbas, Nissar Hussain, Surender Kumar, Shaikh M. Mobin
Summary: The rational construction of free-standing and flexible electrodes for electrochemical energy storage devices is an emerging research focus. In this study, a redox-active metal-organic framework (MOF) was prepared on carbon nanofibers using an in situ approach, resulting in a flexible electrode with high redox-active behavior and unique properties such as high flexibility and lightweight. The prepared electrode showed excellent cyclic retention and rate capability in supercapacitor applications. Additionally, it could be used as a freestanding electrode in flexible devices at different bending angles.
Article
Chemistry, Multidisciplinary
Lishan Zhang, Xiaoting Zhang, Hui Ran, Ze Chen, Yicheng Ye, Jiamiao Jiang, Ziwei Hu, Miral Azechi, Fei Peng, Hao Tian, Zhili Xu, Yingfeng Tu
Summary: Photodynamic therapy (PDT) is a promising local treatment modality in cancer therapy, but its therapeutic efficacy is restricted by ineffective delivery of photosensitizers and tumor hypoxia. In this study, a phototactic Chlorella-based near-infrared (NIR) driven green affording-oxygen microrobot system was developed for enhanced PDT. The system exhibited desirable phototaxis and continuous oxygen generation, leading to the inhibition of tumor growth in mice. This study demonstrates the potential of using a light-driven green affording-oxygen microrobot to enhance photodynamic therapy.
Article
Chemistry, Multidisciplinary
Yujin Li, Jing Xu, Xinqi Luo, Futing Wang, Zhong Dong, Ke-Jing Huang, Chengjie Hu, Mengyi Hou, Ren Cai
Summary: In this study, hollow heterostructured materials were constructed using an innovative template-engaged method as cathodes for zinc-ion batteries. The materials exhibited fast Zn2+ transport channels, improved electrical conductivity, and controlled volume expansion during cycling. The designed structure allowed for an admirable reversible capacity and high coulombic efficiency.
Article
Chemistry, Multidisciplinary
Paritosh Mahato, Shashi Shekhar, Rahul Yadav, Saptarshi Mukherjee
Summary: This study comprehensively elucidates the role of the core and electrostatic surface of metal nanoclusters in catalytic reduction reactions. The electrostatic surface dramatically modulates the reactivity of metal nanoclusters.
Article
Chemistry, Multidisciplinary
Pei Liu, Mengdi Liang, Zhengwei Liu, Haiyu Long, Han Cheng, Jiahe Su, Zhongbiao Tan, Xuewen He, Min Sun, Xiangqian Li, Shuai He
Summary: This study demonstrates a simple and environmentally-friendly method for the synthesis of zinc oxide nanozymes (ZnO NZs) using wasted hop extract (WHE). The WHE-ZnO NZs exhibit exceptional peroxidase-like activity and serve as effective catalysts for the oxidation of 3,3,5,5-tetramethylbenzidine (TMB) in the presence of hydrogen peroxide (H2O2). In addition, a straightforward colorimetric technique for detecting both H2O2 and glucose was developed using the WHE-ZnO NZs as peroxidase-like catalysts.
Article
Chemistry, Multidisciplinary
Hyunkyu Oh, Young Jun Lee, Eun Ji Kim, Jinseok Park, Hee-Eun Kim, Hyunsoo Lee, Hyunjoo Lee, Bumjoon J. Kim
Summary: Mesoporous carbon particles have unique structural properties that make them suitable as support materials for catalytic applications. This study investigates the impact of channel nanostructures on the catalytic activity of porous carbon particles (PCPs) by fabricating PCPs with controlled channel exposure on the carbon surface. The results show that PCPs with highly open channel nanostructures exhibit significantly higher catalytic activity compared to those with closed channel nanostructures.
Article
Chemistry, Multidisciplinary
Yunjie Lu, Zhaohui Li, Zewei Li, Shihao Zhou, Ning Zhang, Jianming Zhang, Lu Zong
Summary: A tough, long-lasting adhesive and highly conductive nanocomposite hydrogel (PACPH) was fabricated via the synergy of interfacial entanglement and adhesion group densification. PACPH possesses excellent mechanical properties, interfacial adhesion strength, and conductivity, making it a promising material for long-term monitoring of human activities and electrocardiogram signals.
Article
Chemistry, Multidisciplinary
Zichao Wei, Audrey Vandergriff, Chung-Hao Liu, Maham Liaqat, Mu-Ping Nieh, Yu Lei, Jie He
Summary: We have developed a simple method to prepare polymer-grafted plasmonic metal nanoparticles with pH-responsive surface-enhanced Raman scattering. By using pH-responsive polymers as ligands, the aggregation of nanoparticles can be controlled, leading to enhanced SERS. The pH-responsive polymer-grafted nanoparticles show high reproducibility and sensitivity in solution, providing a novel approach for SERS without the need for sample pre-concentration.
Article
Chemistry, Multidisciplinary
Melis Ozge Alas Colak, Ahmet Gungor, Merve Buldu Akturk, Emre Erdem, Rukan Genc
Summary: This research investigates the effect of functionalizing carbon dots with hydroxyl polymers on their performance as electrode materials in a supercapacitor. The results show that the functionalized carbon dots exhibit excellent electrochemical performance and improved stability.