Article
Chemistry, Multidisciplinary
Huan Liu, Cheng Yu, Min Lyu, Shiyi Lyu, LiNan Hu, Enhua Xiao, Pengfei Xu
Summary: The development of a targeted and novel albumin-binding strategy has led to the creation of an organic small molecule-based photosensitizer, EB-Ppa, which shows high photodynamic therapeutic efficiency in treating solid tumors. EB-Ppa is stable in serum-containing aqueous media and accumulates effectively in the tumor site through the enhanced permeability and retention (EPR) effect. Treatment with EB-Ppa using photodynamic therapy results in fast shrinkage of breast tumors (4T1 cell line) xenografted in nude mice, due to the singlet oxygen generated by EB-Ppa with laser irradiation. Furthermore, EB-Ppa exhibits negligible toxicity in major organs. These findings indicate the great potential of EB-Ppa for efficient tumor treatment through photodynamic therapy.
Review
Pharmacology & Pharmacy
Chen Chen, Yuqi Zhang, Zhaowei Chen, Huanghao Yang, Zhen Gu
Summary: Using natural cells as drug carriers has become a hot topic in recent years due to their biocompatibility and dynamic properties. Instead of focusing on what cells display, attention is now shifting towards how cells change, including surface protein patterns, morphologies, and in-situ generation of therapeutics, to develop advanced drug delivery systems.
ADVANCED DRUG DELIVERY REVIEWS
(2021)
Review
Pharmacology & Pharmacy
Joydeb Majumder, Tamara Minko
Summary: Nanocarriers offer multiple benefits in targeted drug delivery, such as enhanced bioavailability and high drug loading capacity. Stimuli-responsive nanocarriers have the potential to provide controlled release of therapeutics in response to specific physiological conditions or external stimuli.
EXPERT OPINION ON DRUG DELIVERY
(2021)
Article
Chemistry, Multidisciplinary
Qishu Jiao, Yaxin Zheng, Qinqing Xie, Xuan Luo, Shuyao Zhou, Shicheng Pei, Tingting Zhang, Xiaoxing Wu, Keming Xu, Wenying Zhong
Summary: This study develops an enzyme-responsive nanoplatform using a lonidamine (LND)-derived self-assembling peptide for self-delivery of LND and GSH-activated photosensitizer PSD. This nanoplatform not only enhances the precision of PDT but also mitigates the risk of side effects associated with nonspecific photosensitizer accumulation, and also has a significant positive impact on patient outcomes and the overall field of cancer nanomedicine.
Article
Chemistry, Multidisciplinary
Claire Donohoe, Fabio A. Schaberle, Fabio M. S. Rodrigues, Nuno P. F. Goncalves, Christopher J. Kingsbury, Mariette M. Pereira, Mathias O. Senge, Ligia C. Gomes-da-Silva, Luis G. Arnaut
Summary: The challenge of large molecules crossing cell membranes has hindered the development of new medicines. However, this study shows that altering the atropisomers of a drug can improve cell uptake and therapeutic efficacy. The most effective atropisomer is able to optimize hydrogen bonding with membrane phospholipids, leading to increased cellular uptake and phototoxicity. These findings highlight the importance of atropisomerism in drug development and provide new insights for designing efficient cell-penetrating drugs.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2022)
Article
Pharmacology & Pharmacy
Ying Zhang, Hao Pan, Changxiang Yu, Rui Liu, Bin Xing, Bei Jia, Jiachen He, Xintao Jia, Xiaojiao Feng, Qingqing Zhang, Wenli Dang, Zheming Hu, Xiuping Deng, Pan Guo, Zhidong Liu, Weisan Pan
Summary: The study selected tanshinone IIA (Tan IIA) as the target ligand and chemically modified it in a nanodelivery system, creating Tan-NH2. Tan-NH2 demonstrated good biosafety and tumor-targeting properties, showing anti-tumor effects both in vivo and in vitro.
ASIAN JOURNAL OF PHARMACEUTICAL SCIENCES
(2023)
Article
Chemistry, Multidisciplinary
Luca Ulfo, Andrea Cantelli, Annapaola Petrosino, Paolo Emidio Costantini, Michela Nigro, Francesco Starinieri, Eleonora Turrini, Suleman Khan Zadran, Giampaolo Zuccheri, Roberto Saporetti, Matteo Di Giosia, Alberto Danielli, Matteo Calvaresi
Summary: Using an orthogonal nanoarchitectonics approach, M13 bacteriophages were engineered to specifically target cancer cells with EGFR overexpression, and efficiently deliver photosensitizing molecules for photodynamic therapy at picomolar concentrations.
Article
Chemistry, Multidisciplinary
Chaohui Zhou, Shenglei Hou, Chusen Huang, Nengqin Jia
Summary: In this study, we designed Mn-doped calcium phosphate nanoparticles for targeted delivery of anticancer drugs and MR imaging-guided cancer therapy. The nanoparticles showed good biocompatibility and colloidal stability, and exhibited significant targeted therapeutic effect against BxPC-3 cells.
JOURNAL OF NANOPARTICLE RESEARCH
(2022)
Article
Chemistry, Physical
Qiaorong Tang, Qianqian Li, Lu Shi, Wei Liu, Baoxin Li, Yan Jin
Summary: Due to the complexity and heterogeneity of tumors, multi-mode synergistic therapy is more effective than single treatment modes. In this study, a multifunctional DNA tetrahedron nanoprobe (D-sgc8-DTNS-AgNCs-Anta-21) was designed to achieve chemodynamic therapy (CDT) and gene silencing for synergistic antitumor. The nanoprobe silenced miRNA-21 and induced apoptosis in tumor cells through the production of highly toxic OH. The targeted recognition of aptamers resulted in the death of HeLa cells, while normal cells were unaffected. The diverse functions and programmability of DNA provide a useful way to assemble multifunctional probes for synergistic therapy.
NANOSCALE HORIZONS
(2023)
Article
Biotechnology & Applied Microbiology
Jun-Yong Wu, Yong-Jiang Li, Jiemin Wang, Xiong-Bin Hu, Si Huang, Shilin Luo, Da-Xiong Xiang
Summary: The multifunctional DTX@Ang-EM significantly inhibit the growth of orthotopic GBM with reduced side effects of chemotherapy, providing a new strategy for targeted brain drug delivery and GBM therapy.
JOURNAL OF NANOBIOTECHNOLOGY
(2021)
Article
Multidisciplinary Sciences
Lei Jiang, Sensen Zhou, Xiaoke Zhang, Cheng Li, Shilu Ji, Hui Mao, Xiqun Jiang
Summary: Mitochondria are key targets for photothermal and photodynamic treatment for cancer, but delivery of therapeutics to these organelles remains a challenge. In this study, authors developed a mitochondrial targeted liposomal delivery platform using a dendritic peptide moiety as a mitochondria targeting moiety and demonstrated its targeting and antitumour efficacy in a mouse model of breast cancer.
NATURE COMMUNICATIONS
(2021)
Article
Pharmacology & Pharmacy
Lital Cohen, Yehuda G. Assaraf, Yoav D. Livney
Summary: Prostate cancer is a common cancer in older men and current treatments have limited efficacy. Researchers have developed targeted nanoparticles that can deliver drugs effectively and reduce toxic side effects.
Article
Engineering, Environmental
Huitong Ruan, Shengyu Yao, Songli Wang, Ruifeng Wang, Cao Xie, Haiyan Guo, Weiyue Lu
Summary: By optimizing the structure and stability of RAP12 peptide, a novel ST-RAP12 peptide was developed with enhanced α-helical content, binding affinity, and cellular internalization, showing promising capabilities in penetrating the blood-brain barrier and targeting glioma. ST-RAP12 was also utilized to construct micelles for effective drug delivery to glioma cells, demonstrating significant anti-cancer efficacy.
CHEMICAL ENGINEERING JOURNAL
(2021)
Article
Chemistry, Physical
Aimen Qaiser, Maria Hassan Kiani, Rashida Parveen, Muhammad Sarfraz, Gul Shahnaz, Abbas Rahdar, Pablo Taboada
Summary: This study successfully designed a hyaluronic acid-based nanocarrier system that improves the residence time of clarithromycin at the site of H. pylori infection, potentially enhancing the treatment efficacy.
JOURNAL OF MOLECULAR LIQUIDS
(2022)
Article
Chemistry, Physical
Pengyuan Liu, Yajun Wu, Xiaogang Xu, Xudong Fan, Chuan Sun, Xiaojie Chen, Jindan Xia, Shiting Bai, Li Qu, Huasong Lu, Jing Wu, Jun Chen, Ji-Gang Piao, Zhibing Wu
Summary: A novel nanotechnology-based strategy combining microwaves and photothermal therapy has been developed for the precise target treatment of castration-resistant prostate cancer (CRPC). The nanoplatform achieves accurate drug delivery, precise ablation, and controlled release of the chemotherapeutic agent doxorubicin (DOX) under near-infrared (NIR) irradiation, providing an accurate, controllable, efficient, non-invasive, and safe treatment platform for targeting CRPC.
Article
Nanoscience & Nanotechnology
Nadim Mitri, Kamil Rahme, Giulio Fracasso, Esther Ghanem
Summary: In this study, biocompatible PEGylated AuNPs-scFvD2B nano-complexes were synthesized, which showed minimal protein adsorption affinity, low immunorecognition, and reduced hemolytic activity.
Article
Chemistry, Multidisciplinary
Nicola Peruffo, Giovanni Parolin, Elisabetta Collini, Stefano Corni, Fabrizio Mancin
Summary: The control of light-matter interaction in nanosystems is a significant challenge in the field of innovative photonics applications. This study focuses on the investigation of hybrid nanosystem suspensions, formed by coupling cationic gold nanoparticles with tetraphenyl porphyrins. The results demonstrate the important role of parameters such as nanoparticle dimension, solution pH, and the ratio between nanoparticles and dye concentration in achieving control over nanosystems.
Article
Biochemistry & Molecular Biology
Chiara Bellini, Salvatore Antonucci, Lucia Morillas-Becerril, Sara Scarpa, Regina Tavano, Fabrizio Mancin, Fabio Di Lisa, Emanuele Papini
Summary: The study demonstrated the effectiveness of utilizing two formulations of poly(lipoic acid)-based nanoparticles (NPs) in combating radical damage and ROS formation in various cell types. Results indicate that NPs could effectively protect against myocardial cell damage induced by ischemic reperfusion injury.
Article
Chemistry, Physical
Nicola Peruffo, Fabrizio Mancin, Elisabetta Collini
Summary: The ultrafast dynamics of plexcitonic materials, influenced by other states, have longer time constants than typical values found in literature and can be modulated, opening up potential prospects for modifying rates of chemical reactions.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2022)
Article
Biochemistry & Molecular Biology
Francesca Moret, Luca Menilli, Celeste Milani, Giorgia Di Cintio, Chiara Dalla Torre, Vincenzo Amendola, Marta De Zotti
Summary: In the field of bioactive peptides, peptaibols are a unique class of compounds produced by Trichoderma fungi that are membrane-active and can induce plant defense responses. Among these compounds, trichogin analogs have shown potent activity against phytopathogens and potential as a sustainable alternative to copper-based plant protection. This study investigated the activity of trichogin analogs against breast cancer cells and normal cells, finding that certain analogs displayed cytotoxicity against cancer cells and could be anchored to gold nanoparticles for targeted drug delivery.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Cell Biology
Stefania Cane, Roza Maria Barouni, Marina Fabbi, John Cuozzo, Giulio Fracasso, Annalisa Adamo, Stefano Ugel, Rosalinda Trovato, Francesco De Sanctis, Mauro Giacca, Rita Lawlor, Aldo Scarpa, Borislav Rusev, Gabriella Lionetto, Salvatore Paiella, Roberto Salvia, Claudio Bassi, Susanna Mandruzzato, Silvano Ferrini, Vincenzo Bronte
Summary: Preclinical studies have shown that myeloid cells can suppress antitumor immunity by degrading L-arginine, but differences in ARG1 expression and function in rodents and humans have hindered clinical translation. This study discovered that neutrophil extracellular traps (NETs) released by activated neutrophils in patients with PDAC create a microdomain where cathepsin S (CTSS) cleaves human ARG1 (hARG1) into different forms with enhanced enzymatic activity. These NET-associated hARG1 molecules suppress T lymphocytes, but their proliferation can be restored by blocking CTSS cleavage or using hARG1-specific monoclonal antibodies, suggesting potential therapeutic strategies for PDAC.
SCIENCE TRANSLATIONAL MEDICINE
(2023)
Article
Materials Science, Multidisciplinary
Nicola Peruffo, Fabrizio Mancin, Elisabetta Collini
Summary: Two-dimensional electronic spectroscopy (2DES) is employed to study the quantum coherent interactions of colloidal plexciton nanohybrids, revealing the nonlinear photophysical processes and advancing the understanding and exploitation of these nanomaterials.
ADVANCED OPTICAL MATERIALS
(2023)
Review
Biochemistry & Molecular Biology
Alessia Dallatana, Linda Cremonesi, Maddalena Trombetta, Giulio Fracasso, Riccardo Nocini, Luca Giacomello, Giulio Innamorati
Summary: The human genome contains multiple GPCRs specialized in sensing various extracellular cues, including light, odorants, nutrients, and hormones. These GPCRs play a crucial role in regulating glucose homeostasis, especially for beta cells. The rise of type 2 diabetes in pediatric age may be due to changes in lifestyle and hormonal balance, highlighting the need for tailored treatments for young patients.
Review
Nanoscience & Nanotechnology
Nadim Mitri, Kamil Rahme, Giulio Fracasso, Esther Ghanem
Summary: Green nanotechnology produces biocompatible gold nanoparticles (AuNPs) with inherent anti-microbial, anti-viral, and anti-tumour properties, which are gaining popularity in prostate cancer (PC) nanotherapy. This review compares and summarizes data from studies published between 2015 and 2022, highlighting the major biological compounds and outcomes of in vitro and in vivo applications of green or biosynthesized AuNPs in PC theranostics. The use of green AuNPs shows promising antiproliferative characteristics in PC, with various apoptosis-related mechanisms and successful delivery of biological compounds. Furthermore, green AuNPs offer a potential modality for targeted cancer therapy and address ethical concerns and toxicity risks in clinical trials.
ADVANCES IN NATURAL SCIENCES-NANOSCIENCE AND NANOTECHNOLOGY
(2023)
Article
Nanoscience & Nanotechnology
Monira Sarkis, Georges Minassian, Nadim Mitri, Kamil Rahme, Giulio Fracasso, Roland El Hage, Esther Ghanem
Summary: Despite the availability of therapeutic agents for prostate cancer (PC), there is still a lack of effective and safe treatment measures. Developing a simple approach to target PC with specific antibodies remains a challenge. In this study, D2B monoclonal antibodies against prostate-specific membrane antigen (PSMA) were used to functionalize gold nanoparticles (AuNPs), resulting in favorable physicochemical and biological properties for specific binding to PC.
ACS APPLIED BIO MATERIALS
(2023)
Article
Chemistry, Physical
Sebastian Franco-Ulloa, Andrea Cesari, Laura Riccardi, Federico De Biasi, Daniele Rosa-Gastaldo, Fabrizio Mancin, Marco De Vivo, Federico Rastrelli
Summary: Nanoparticle-assisted nuclear magnetic resonance (NMR) chemosensing is a technique that uses monolayer-protected nanoparticles as supramolecular hosts to detect small molecules in complex mixtures. The structure-sensitivity relationships that determine the detection limits of this technique are still not well understood. This study combines NMR spectroscopy and atomistic molecular dynamics simulations to investigate the factors that affect the sensitivity of different NMR chemosensing experiments. The results show that the intensity of the observed signals is correlated with the spin-spin interactions between the analytes and the nanoparticles, as well as the analytes and the nanoparticles' solvation molecules.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2023)
Article
Multidisciplinary Sciences
Giulio Fracasso, Elisabetta Falvo, Giada Tisci, Gianluca Sala, Gianni Colotti, Sara Cingarlini, Claudia Tito, Sandra Bibbo, Cristina Frusteri, Elisa Tremante, Elena Giordani, Patrizio Giacomini, Pierpaolo Ceci
Summary: The study demonstrated the effectiveness of utilizing the HFt-based drug carrier The-0504 to deliver Genz-644282 inhibitor to CD71-expressing tumors, showing promising anti-tumor activity. The drug exhibited long persistence in rat serum, allowing for reduced administration frequency without compromising therapeutic efficacy.
Article
Nanoscience & Nanotechnology
Monira Sarkis, Georges Minassian, Nadim Mitri, Kamil Rahme, Giulio Fracasso, Roland El Hage, Esther Ghanem
Summary: In this study, D2B monoclonal antibodies were functionalized onto gold nanoparticles to achieve specific binding to prostate cancer cells. The successful binding of D2B to AuNPs was confirmed by DLS and UV-vis spectroscopy, suggesting the potential use of this system for targeted drug delivery in prostate cancer theranostics.
ACS APPLIED BIO MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Andrea Cesari, Daniele Rosa-Gastaldo, Alessandro Pedrini, Federico Rastrelli, Enrico Dalcanale, Roberta Pinalli, Fabrizio Mancin
Summary: This study presents a novel strategy for NMR chemosensors by utilizing self-assembled cavity structures on silica nanoparticles. These nanohybrids demonstrate selective detection of physiologically relevant compounds through STD-based NMR experiments.
CHEMICAL COMMUNICATIONS
(2022)
Article
Chemistry, Multidisciplinary
Marianna Tosato, Matteo Pelosato, Sara Franchi, Abdirisak Ahmed Isse, Nora Veronica May, Giordano Zanoni, Fabrizio Mancin, Paolo Pastore, Denis Badocco, Mattia Asti, Valerio Di Marco
Summary: This study synthesized three novel polyazamacrocyclic ligands as potential chelators for medical copper radioisotopes, and investigated their coordination properties with copper in aqueous solution. It was found that TRI4S and TE4S can stabilize both copper oxidation states, making them promising candidates for application in nuclear medicine.
NEW JOURNAL OF CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Laetitia Bardet, Herve Roussel, Stefano Saroglia, Masoud Akbari, David Munoz-Rojas, Carmen Jimenez, Aurore Denneulin, Daniel Bellet
Summary: The thermal instability of silver nanowires leads to increased electrical resistance in AgNW networks. Understanding the relationship between structural and electrical properties of AgNW networks is crucial for their integration as transparent electrodes in flexible optoelectronics. In situ X-ray diffraction measurements were used to study the crystallographic evolution of Ag-specific Bragg peaks during thermal ramping, revealing differences in thermal and structural transitions between bare and SnO2-coated AgNW networks.
Article
Chemistry, Multidisciplinary
Nathalia Cancino-Fuentes, Arnau Manasanch, Joana Covelo, Alex Suarez-Perez, Enrique Fernandez, Stratis Matsoukis, Christoph Guger, Xavi Illa, Anton Guimera-Brunet, Maria V. Sanchez-Vives
Summary: This study provides a comprehensive characterization of graphene-based solution-gated field-effect transistors (gSGFETs) for brain recordings, highlighting their potential clinical applications.
Article
Chemistry, Multidisciplinary
Sikandar Aftab, Hailiang Liu, Dhanasekaran Vikraman, Sajjad Hussain, Jungwon Kang, Abdullah A. Al-Kahtani
Summary: This study examines the effects of hybrid nanoparticles made of NiO@rGO and NiO@CNT on the active layers of polymer solar cells and X-ray photodetectors. The findings show that these hybrid nanoparticles can enhance the charge carrier capacities and exciton dissociation properties of the active layers. Among the tested configurations, the NiO@CNT device demonstrates superior performance in converting sunlight into electricity, and achieves the best sensitivity for X-ray detection.
Article
Chemistry, Multidisciplinary
Hyo Jung Shin, Seung Gyu Choi, Fengrui Qu, Min-Hee Yi, Choong-Hyun Lee, Sang Ryong Kim, Hyeong-Geug Kim, Jaewon Beom, Yoonyoung Yi, Do Kyung Kim, Eun-Hye Joe, Hee-Jung Song, Yonghyun Kim, Dong Woon Kim
Summary: This study investigates the role of SOX9 in reactive astrocytes following ischemic brain damage using a PLGA nanoparticle plasmid delivery system. The results demonstrate that PLGA nanoparticles can reduce ischemia-induced neurological deficits and infarct volume, providing a potential opportunity for stroke treatment.
Article
Chemistry, Multidisciplinary
Anurag Chaudhury, Koushik Debnath, Nikhil R. Jana, Jaydeep K. Basu
Summary: The study investigates the interaction between nanoparticles and cell membranes, and identifies key parameters, including charge, crowding, and membrane fluidity, that determine the adsorbed concentration and unbinding transition of nanoparticles.
Article
Chemistry, Multidisciplinary
Sina Sadeghi, Fazel Bateni, Taekhoon Kim, Dae Yong Son, Jeffrey A. Bennett, Negin Orouji, Venkat S. Punati, Christine Stark, Teagan D. Cerra, Rami Awad, Fernando Delgado-Licona, Jinge Xu, Nikolai Mukhin, Hannah Dickerson, Kristofer G. Reyes, Milad Abolhasani
Summary: In this study, an autonomous approach for the development of lead-free metal halide perovskite nanocrystals is presented, which integrates a modular microfluidic platform with machine learning-assisted synthesis modeling. This approach enables rapid and optimized synthesis of copper-based lead-free nanocrystals.
Article
Chemistry, Multidisciplinary
Zahir Abbas, Nissar Hussain, Surender Kumar, Shaikh M. Mobin
Summary: The rational construction of free-standing and flexible electrodes for electrochemical energy storage devices is an emerging research focus. In this study, a redox-active metal-organic framework (MOF) was prepared on carbon nanofibers using an in situ approach, resulting in a flexible electrode with high redox-active behavior and unique properties such as high flexibility and lightweight. The prepared electrode showed excellent cyclic retention and rate capability in supercapacitor applications. Additionally, it could be used as a freestanding electrode in flexible devices at different bending angles.
Article
Chemistry, Multidisciplinary
Lishan Zhang, Xiaoting Zhang, Hui Ran, Ze Chen, Yicheng Ye, Jiamiao Jiang, Ziwei Hu, Miral Azechi, Fei Peng, Hao Tian, Zhili Xu, Yingfeng Tu
Summary: Photodynamic therapy (PDT) is a promising local treatment modality in cancer therapy, but its therapeutic efficacy is restricted by ineffective delivery of photosensitizers and tumor hypoxia. In this study, a phototactic Chlorella-based near-infrared (NIR) driven green affording-oxygen microrobot system was developed for enhanced PDT. The system exhibited desirable phototaxis and continuous oxygen generation, leading to the inhibition of tumor growth in mice. This study demonstrates the potential of using a light-driven green affording-oxygen microrobot to enhance photodynamic therapy.
Article
Chemistry, Multidisciplinary
Yujin Li, Jing Xu, Xinqi Luo, Futing Wang, Zhong Dong, Ke-Jing Huang, Chengjie Hu, Mengyi Hou, Ren Cai
Summary: In this study, hollow heterostructured materials were constructed using an innovative template-engaged method as cathodes for zinc-ion batteries. The materials exhibited fast Zn2+ transport channels, improved electrical conductivity, and controlled volume expansion during cycling. The designed structure allowed for an admirable reversible capacity and high coulombic efficiency.
Article
Chemistry, Multidisciplinary
Paritosh Mahato, Shashi Shekhar, Rahul Yadav, Saptarshi Mukherjee
Summary: This study comprehensively elucidates the role of the core and electrostatic surface of metal nanoclusters in catalytic reduction reactions. The electrostatic surface dramatically modulates the reactivity of metal nanoclusters.
Article
Chemistry, Multidisciplinary
Pei Liu, Mengdi Liang, Zhengwei Liu, Haiyu Long, Han Cheng, Jiahe Su, Zhongbiao Tan, Xuewen He, Min Sun, Xiangqian Li, Shuai He
Summary: This study demonstrates a simple and environmentally-friendly method for the synthesis of zinc oxide nanozymes (ZnO NZs) using wasted hop extract (WHE). The WHE-ZnO NZs exhibit exceptional peroxidase-like activity and serve as effective catalysts for the oxidation of 3,3,5,5-tetramethylbenzidine (TMB) in the presence of hydrogen peroxide (H2O2). In addition, a straightforward colorimetric technique for detecting both H2O2 and glucose was developed using the WHE-ZnO NZs as peroxidase-like catalysts.
Article
Chemistry, Multidisciplinary
Hyunkyu Oh, Young Jun Lee, Eun Ji Kim, Jinseok Park, Hee-Eun Kim, Hyunsoo Lee, Hyunjoo Lee, Bumjoon J. Kim
Summary: Mesoporous carbon particles have unique structural properties that make them suitable as support materials for catalytic applications. This study investigates the impact of channel nanostructures on the catalytic activity of porous carbon particles (PCPs) by fabricating PCPs with controlled channel exposure on the carbon surface. The results show that PCPs with highly open channel nanostructures exhibit significantly higher catalytic activity compared to those with closed channel nanostructures.
Article
Chemistry, Multidisciplinary
Yunjie Lu, Zhaohui Li, Zewei Li, Shihao Zhou, Ning Zhang, Jianming Zhang, Lu Zong
Summary: A tough, long-lasting adhesive and highly conductive nanocomposite hydrogel (PACPH) was fabricated via the synergy of interfacial entanglement and adhesion group densification. PACPH possesses excellent mechanical properties, interfacial adhesion strength, and conductivity, making it a promising material for long-term monitoring of human activities and electrocardiogram signals.
Article
Chemistry, Multidisciplinary
Zichao Wei, Audrey Vandergriff, Chung-Hao Liu, Maham Liaqat, Mu-Ping Nieh, Yu Lei, Jie He
Summary: We have developed a simple method to prepare polymer-grafted plasmonic metal nanoparticles with pH-responsive surface-enhanced Raman scattering. By using pH-responsive polymers as ligands, the aggregation of nanoparticles can be controlled, leading to enhanced SERS. The pH-responsive polymer-grafted nanoparticles show high reproducibility and sensitivity in solution, providing a novel approach for SERS without the need for sample pre-concentration.
Article
Chemistry, Multidisciplinary
Melis Ozge Alas Colak, Ahmet Gungor, Merve Buldu Akturk, Emre Erdem, Rukan Genc
Summary: This research investigates the effect of functionalizing carbon dots with hydroxyl polymers on their performance as electrode materials in a supercapacitor. The results show that the functionalized carbon dots exhibit excellent electrochemical performance and improved stability.