Article
Nanoscience & Nanotechnology
Juan Huang, Hongfei Gu, Xiaowei Feng, Guo Wang, Zhengbo Chen
Summary: This paper reports a simple method to synthesize a N-doped Ti3C2Tx MXene, which serves as a support platform for developing MXene-based nanozymes. By anchoring copper nanoparticles on N-doped Ti3C2Tx, Cu nanoparticles/N-doped Ti3C2Tx with enhanced peroxidase-like activity and structural stability were prepared. These nanozymes exhibited excellent performance in colorimetric biosensors, with high sensitivity, selectivity, and remarkable stability.
ACS APPLIED NANO MATERIALS
(2022)
Article
Chemistry, Analytical
Na Tao, Ying Xu, Liqiang Wang, Wenjie Yang, You-Nian Liu
Summary: This study synthesized Co4N@NC nanoparticles with high catalytic activity and stability through the pyrolysis of Co-MOF, which can be used for the detection of H2O2 and glucose with detection limits of 0.032 mu M and 0.29 mu M, respectively.
MICROCHEMICAL JOURNAL
(2021)
Article
Chemistry, Analytical
Yu Liu, Xiaoyi Yan, Yutong Tang, Nannan Lu, Tingting Zhang, Zhiqian Xu, Yue Xing, Puyu Zhao, Meihan Liu, Yunxue Zhu, Zhiquan Zhang, Ming Yang
Summary: In this work, Co nanoparticles decorated bamboo-like N-doped carbon nanotubes (Co-BNCNTs) were designed as a novel signal amplification platform for dopamine (DA) sensing. The Co-BNCNTs/GCE biosensor exhibited good stability, selectivity, a wide detection range, and a low detection limit. Furthermore, this study presented an effective method for the synthesis of metal nanoparticles encapsulated into CNTs catalysts as nanozymes for biosensing applications.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2022)
Article
Engineering, Environmental
Mingqi Xu, Wenwen Wang, Hong Han, Yupu Wei, Jingquan Sha, Guodong Liu
Summary: To enhance the peroxides-like activities of metal sulfides as nanozymes, a Co3S4/MoS2 heterostructure was designed and fabricated, anchored on N-doped porous carbon (NPC). The results showed that Co3S4/MoS2@NPC had improved electron transfer ability and higher affinity to substrates compared to other nanozymes, resulting in enhanced catalytic activity and selectivity.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Biochemical Research Methods
Xiaoyan Cao, Shuang Zhao, Xiangwei Liu, Xixi Zhu, Yan Gao, Qingyun Liu
Summary: In this study, CeO2/Co3O4@N-doped hollow carbon microspheres were investigated as nanozymes with peroxidase-like activity. The nanozymes exhibited high catalytic activity and were used to fabricate a convenient and efficient biosensor for the determination of H2O2 and quercetin. CeO2/Co3O4@NCH can be widely applied in the fields of biosensing, food, and environmental monitoring.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2022)
Article
Pharmacology & Pharmacy
Thi Tuong Vi Truong, Chien-Chang Chen, Selvaraj Rajesh Kumar, Chih-Chien Hu, Dave W. Chen, Yu-Kuo Liu, Shingjiang Jessie Lue
Summary: Spherical silver nanoparticles and silver nanoprisms were synthesized and decorated on graphene oxide nanosheets, showing promising antibacterial properties against Gram-positive bacteria, especially at high concentrations. The levels of reactive oxygen species produced in the bacteria-nanomaterial mixtures were highly correlated to the antibacterial efficacy values.
Article
Chemistry, Physical
Lizhi Zhao, Didi Si, Yaxiang Zhao, Lixian Wang, Huiqin An, Hui Ye, Qingping Xin, Yuzhong Zhang
Summary: In this paper, a hybrid nanosheet with peroxidase-like activity is constructed by incorporating non-precious copper nanocomposites onto nanosheets of metal organic framework (MOF). The synthesized nanohybrids show enhanced catalytic performance and substrate affinity compared to free copper composites and pure MOFs. These nanohybrids are successfully applied to decolorization of Congo Red and detection of glucose with high efficiency and sensitivity.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2022)
Article
Chemistry, Analytical
Yi Xia, Jiaxin Zhou, Yanying Liu, Yutong Liu, Ke Huang, Huimin Yu, Xue Jiang, Xiaoli Xiong
Summary: Due to their high catalytic activity, stability, and low cost, nanozymes with oxidase-like activity have attracted widespread interest. In this study, a mixed valence Ce-MOF (MVCM) with enhanced oxidase-like activity was synthesized using the dielectric barrier discharge microplasma method. A colorimetric sensor for dopamine based on the redox properties of Ce3+/Ce4+ in MVCM was developed and successfully applied for dopamine detection in sweat.
Article
Chemistry, Physical
Jinbo Hao, Feng Wei, Xinhui Zhang, Long Li, Changcheng Chen, Ge Wu, Liyuan Wu, Dan Liang, Xiaoguang Ma, Pengfei Lu, Haizhi Song
Summary: By utilizing first principles calculations, Li-decorated N-doped PG was identified as a promising material for hydrogen storage, with a maximum hydrogen gravimetric density of 7.88 wt%. The study provides valuable insights into the potential of Li-decorated N-doped PG as an efficient hydrogen storage material.
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
(2021)
Article
Chemistry, Analytical
Ping Li
Summary: This study successfully prepared nitrogen-doped carbon dots with peroxidase-like activity and explored their catalytic mechanism through a series of experimental methods and theoretical calculations. The results of this study provide a new approach for synthesizing artificial peroxidases for biological and environmental applications.
Article
Chemistry, Multidisciplinary
Jing Yang, Rene Huebner, Jiangwei Zhang, Hao Wan, Yuanyuan Zheng, Honglei Wang, Haoyuan Qi, Lanqi He, Yi Li, Amare Aregahegn Dubale, Yujing Sun, Yuting Liu, Daoling Peng, Yuezhong Meng, Zhikun Zheng, Jan Rossmeisl, Wei Liu
Summary: A hierarchically porous PtNi nanoframe/N-doped graphene aerogel electrocatalyst has been developed with outstanding performance toward methanol oxidation reaction, exhibiting exceptional stability and significantly higher activity compared to commercial Pt/C.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Chemistry, Multidisciplinary
Jinghua Liu, Xiong He, Fei Guo, Baosheng Liu, Zijun Sun, Li Zhang, Haixin Chang
Summary: In this study, a VN/NCNT/NCN hybrid electrode material was successfully fabricated and exhibited excellent performance in supercapacitors, including high specific capacitance and good cycling stability.
Article
Chemistry, Analytical
Longwei Wang, Bo Li, Zhen You, Aizhu Wang, Xuanyu Chen, Gaojing Song, Ling Yang, Dan Chen, Xin Yu, Jing Liu, Chunying Chen
Summary: The article introduces a novel nanozyme with good stability and superior catalytic kinetics, capable of sensitively detecting biomolecules such as glucose and glutathione. The development of this artificial nanozyme is expected to contribute to sensitive detection of other biomolecules in physiological conditions in the future.
ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Tao Chen, Jinmin Cao, Xiaofang Bao, Yu Peng, Li Liu, Wensheng Fu
Summary: Artificial nanozymes are designed to achieve superb catalytic efficiency and selectivity surpassing natural enzymes, while maintaining higher stability. This technology has been widely applied at the intersection of nanotechnology and biomedicine. By utilizing nanostructure engineering, N-doping, and carbon coating, a Co@N-CNTs hybrid nanocomposite was fabricated to mimic oxidase activity, demonstrating excellent selectivity and sensitivity for detecting ascorbic acid.
Article
Chemistry, Multidisciplinary
Iram Amin, Sajad Ahmad Bhat, Murtaza Manzoor Bhat, Feroz Ahmad Sofi, Aamir Y. Bhat, Pravin P. Ingole, Ritwik Mondal, Musthafa Ottakam Thotiyl, Mohsin Ahmad Bhat
Summary: Direct urea fuel cells (DUFCs) provide an environmentally friendly and cost-effective way to convert wastewater into energy. However, the lack of efficient, cost-effective, and electrochemically stable electrocatalysts for the urea electro-oxidation reaction (UOR) hinders the practical application of DUFCs. This study explores the design and development of N-doped graphene-supported platinum plus silver alloy nanohybrids as potential UOR electrocatalysts. The results demonstrate that the Pt50Ag50-NGr nanohybrid exhibits the best UOR electrocatalytic performance, making it a promising anode material for DUFCs. This is further demonstrated through the design of a prototype urea-H2O2 fuel cell using Pt50Ag50-NGr as the anode material, which shows good performance in terms of open circuit voltage and power density.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Alexander Bunge, Alexandru Chiriac, Mihaela Sofronie, Izabell Craciunescu, Alin Sebastian Porav, Rodica Turcu
Summary: Shape memory alloys, especially ferromagnetic shape memory alloys, are being explored as materials for manufacturing stents. Iron-palladium alloys have the potential to be used in self-expanding temporary stents thanks to their optimal degradation rate. In this study, sulfated pectin was synthesized and used as a coating on various iron-palladium alloys, resulting in improved anticoagulant properties.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Multidisciplinary
Cristina-Georgiana Spelmezan, Gabriel Katona, Laszlo Csaba Bencze, Csaba Paizs, Monica Ioana Tosa
Summary: A new biocatalyst was prepared by entrapping lipase B from Candida antarctica into nanofibers. The biocatalyst showed high activity, selectivity, and stability for synthetic applications, with more than 95% activity retained after 10 reaction cycles. It was efficient for the enzymatic resolution of nine racemic phenothiazinyl-ethanols, particularly for bulky substrates like N-ethyl and N-butyl derivatives.
REACTION CHEMISTRY & ENGINEERING
(2023)
Article
Chemistry, Analytical
Lidia Magerusan, Florina Pogacean, Bogdan Ionut Cozar, Stela Pruneanu
Summary: Food safety has become a concern due to the increase in living standards. To address this, a highly sensitive method for detecting Sunset Yellow was proposed, using a glassy carbon electrode modified with few-layer graphenes. The modified electrode showed good linearity, selectivity, and sensitivity, and was successfully applied in quantification of Sunset Yellow. The research provides an effective approach for rapid testing of food additives.
Article
Chemistry, Physical
Dragos-Viorel Cosma, Cristian Tudoran, Maria Coros, Crina Socaci, Alexandra Urda, Alexandru Turza, Marcela-Corina Rosu, Lucian Barbu-Tudoran, Ioana Stanculescu
Summary: Surface modification of cotton and leather substrates with cold atmospheric pressure plasma (CAPP) and TiO2-SiO2-reduced graphene oxide composites in dispersion form improved their morpho-structural properties and photocatalytic activity. The study evaluated the effect of CAPP pre-treatment, organic dispersion coating, and TS/GR composites on the surfaces of cotton and leather. The success of the coating formulations was confirmed through SEM analysis and UV-Vis spectroscopy, and the self-cleaning ability of the modified samples was demonstrated through photocatalytic discoloration of berry juice stains under UV light.
Article
Chemistry, Multidisciplinary
Florina Pogacean, Codruta Varodi, Lidia Magerusan, Stela Pruneanu
Summary: This article presents the development of an electrochemical sensor based on graphene/glassy carbon electrode for trace level detection of nitrite in water samples. The sensor exhibits remarkable enhanced sensing response towards nitrite compared to the bare electrode (three orders of magnitude higher). It also demonstrates excellent operational stability, repeatability, and interference capability, and shows excellent results in the practical application test in commercially available waters.
Article
Chemistry, Multidisciplinary
Izabell Craciunescu, George Marian Ispas, Alexandra Ciorita, Cristian Leostean, Erzsebet Illes, Rodica Paula Turcu
Summary: Our research focuses on the synthesis of magnetic dental composite materials that overcome the limitations of using magnetic nanoparticles in dental applications. The composites were prepared using a preparation flow containing several integrated reaction steps. We performed a thorough characterization of the dental magnetic composites to demonstrate their effectiveness in addressing each limitation. The results showed that the different components of the composites provide specific benefits in dental interventions, such as biocompatibility, antimicrobial effects, increased mechanical strength, and improved esthetics. Additionally, the magnetic properties enable innovative application approaches and help reduce dental caries and microfractures.
Article
Materials Science, Multidisciplinary
Simona Gutoiu, Florina Pogacean, Lidia Magerusan, Maria Olimpia Miclaus, Oana Grad, Ioan-Ovidiu Pana, Stela Pruneanu
Summary: Manganese doped crystalline copper oxide (CuO:Mn) and undoped CuO were prepared by the hydrothermal method and characterized using XRD, TEM/SEM, and XPS. The CuO:Mn/SPE electrode showed high sensitivity and a low limit of detection for dopamine oxidation. The developed sensor also exhibited good results in testing a pharmaceutical drug, indicating its potential biomedical application.
Article
Microbiology
Alexandra Ciorita, Maria Suciu, Maria Coros, Codruta Varodi, Florina Pogacean, Lidia Magerusan, Valentin Mirel, Raluca-Ioana Stefan-van Staden, Stela Pruneanu
Summary: Bacterial infections pose a major threat due to antibiotic resistance, driving the need for new drugs or improved resources. Nanomaterials with high surface area and bactericidal properties show promise in combatting microbial infections. In this study, graphene decorated with silver nanoparticles (5 wt% Ag) exhibited inhibitory capacity against S. aureus and E. coli. The hybrid material was incubated with a high-efficiency particulate air (HEPA) filter, resulting in a modified filter with enhanced antibacterial properties, particularly against Gram-negative bacteria. The modified HEPA filter significantly affected the colony forming unit capacity of bacteria, suggesting its potential to improve existing technology.
Article
Polymer Science
Tamara-Rita Ovari, Arpad Ferenc Szoke, Gabriel Katona, Gabriella Stefania Szabo, Liana Maria Muresan
Summary: This research aimed to develop temporary coatings that effectively protect metal surfaces and are easy to remove. The chitosan/epoxy double layers on zinc exhibited tailor-made and peelable-on-demand characteristics. The chitosan sublayer improved adhesion, while the hydrophilic epoxy layer and the tendency of chitosan to swell in acidic conditions allowed for easy removal.
Review
Pharmacology & Pharmacy
Alexandra Pusta, Mihaela Tertis, Izabell Craciunescu, Rodica Turcu, Simona Mirel, Cecilia Cristea
Summary: This review provides a critical overview of recent advancements in the use of magnetic nanoparticles in drug delivery, including their classification, characteristics, synthesis and functionalization methods, limitations, and examples of magnetic drug delivery systems incorporating chemotherapeutics or RNA.
Article
Chemistry, Multidisciplinary
Nikolaos Chazapis, Michalis Stavrou, Georgia Papaparaskeva, Alexander Bunge, Rodica Turcu, Theodora Krasia-Christoforou, Stelios Couris
Summary: This study focuses on the synthesis and characterization of iridium (Ir)-based nanohybrids with different chemical compositions. The nanohybrids, including PVP-IrO2, PVP-Ir/IrO2, and non-coated Ir/IrO2 nanoparticles, were synthesized using various methods and characterized through XPS and STEM. The results demonstrate that these nanohybrids exhibit exceptional nonlinear optical (NLO) response and optical limiting (OL) efficiency, making them potential competitors in photonic and optoelectronic applications. Moreover, the choice of synthetic method significantly influences the NLO properties of the nanohybrids, suggesting the possibility of tailor-made NLO properties for specific applications in photonics and optoelectronics.
Article
Chemistry, Physical
Alexandra Urda, Teodora Radu, Crina Socaci, Veronica Floare-Avram, Dragos Cosma, Marcela Corina Rosu, Maria Coros, Stela Pruneanu, Florina Pogacean
Summary: This study evaluates the role of nitrogen-doped graphene in the photocatalytic degradation of sulfamethoxazole. The results demonstrate that nitrogen-doped graphene greatly enhances the photocatalytic activity of the catalyst, leading to almost 100% degradation efficiency under sunlight exposure.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
(2022)
Article
Chemistry, Analytical
Mengmeng Guo, Na Luo, Yueling Bai, Zhenggang Xue, Qingmin Hu, Jiaqiang Xu
Summary: A porous heterostructure WO3-C/In2O3 was designed and prepared for a miniature H2 sensor, which showed higher response value, lower operating temperature, fast response-recovery speed, and low limit of detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Feng Hu, Hui Hu, Yuting Li, Xiaohui Wang, Xiaowen Shi
Summary: Arsenic contamination in water bodies is a significant health risk. This study developed a chitosan-catechol modified electrode for rapid and accurate detection of trace amounts of arsenic. The modified electrode demonstrated good detection capability and resistance to ionic interference, making it suitable for in situ detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yantao Zhang, Qian Liu, Tao Tian, Chunhua Xu, Pengli Yang, Lianju Ma, Yi Hou, Hui Zhou, Yongjun Gan
Summary: In this study, a lysosome-targeting buffering fluorogenic probe (Lyso-BFP) was designed and synthesized, demonstrating excellent photostability, pH specificity, and responsiveness to lysosomal acidification in living cells. The performance of Lyso-BFP in pH sensing was attributed to the inhibition of the photo-induced electron transfer process. Lyso-BFP allowed for wash-free imaging and long-term real-time monitoring of lysosome pH changes based on its off-on fluorescence behavior and buffer strategy.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Wei Cai, Wenbo Sun, Jiayue Wang, Xiaokui Huo, Xudong Cao, Xiangge Tian, Xiaochi Ma, Lei Feng
Summary: In this study, a near-infrared fluorescent probe HCBG was developed for imaging of alpha-GLC. HCBG exhibited excellent selectivity and sensitivity towards alpha-GLC in complex bio-samples, and showed good cell permeability for in situ real-time imaging. Through the high-throughput screening system established by HCBG, a natural alpha-GLC inhibitor was successfully isolated and identified. This study provides a novel fluorescence visualization tool for discovering and exploring the biological functions of diabetes-related gut microbiota, and a high-throughput screening approach for alpha-GLC inhibitor.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Trey W. Pittman, Xi Zhang, Chamindie Punyadeera, Charles S. Henry
Summary: Heart failure is a growing epidemic and a significant clinical and public health problem. Researchers have developed a portable and affordable diagnostic device for heart failure that can be used at the point-of-care, providing a valid alternative to current diagnostics approaches.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Anders O. Tjell, Barbara Jud, Roland Schaller-Ammann, Torsten Mayr
Summary: An optical hydrogen peroxide sensor based on catalytic degradation and the detection of produced oxygen is presented. The sensor offers higher resolution and better sensitivity at lower H2O2 concentrations. By removing O2 from the sample solution, a more sensitive O2 sensor can be used for measurement. The sensor has been successfully applied in a flow-through cell to measure H2O2 concentration in different flow rates.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Seong Jae Kim, Ji-hun Jeong, Gaabhin Ryu, Yoon Sick Eom, Sanha Kim
Summary: Surface-enhanced Raman spectroscopy (SERS) is a high-sensitivity, label-free detection method with various analytical applications. Researchers have developed a hydrophobic SERS substrate based on engineered carbon nanotube arrays (CNT-SERS) and studied the role of structural design at both micro and nanoscales. The substrate demonstrated controlled self-enrichment capability and enhanced sensitivity, with a significant increase in the SERS signal. The study also proposed a theoretical model and a concentration strategy inspired by plants for analyte deposition on microarrays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Dan Zhao, Renjun Jiang, Xiaoqiang Liu, Subbiah Alwarappan
Summary: In this study, a novel ternary composite material was constructed by assembling cerium vanadate nanorods on reduced graphene oxide-microcrystalline cellulose nanosheets, and it was used for real-time monitoring of the concentration of superoxide anions in vivo. The ternary composite showed excellent conductivity, large surface area, and abundant active sites, leading to a wider linear range, high sensitivity, low detection limit, and fast response time for superoxide anion detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Tengfei Wang, Liwen Wang, Guang Wu, Dating Tian
Summary: In this study, a covalent organic framework material TaTp-COF with porous and uniform spheres was successfully prepared via hydrothermal reaction, and it was found to significantly enhance the aggregation-induced emission (AIE) of berberine. The unique emission properties of berberine on TaTp-COF were studied and utilized for the sensitive detection of berberine.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Lin Li, Yilei Ding, Lei Xu, Shuoran Chen, Guoliang Dai, Pengju Han, Lixin Lu, Changqing Ye, Yanlin Song
Summary: In this study, a novel TTI based on a ratiometric fluorescent nanosensor is designed, which has the advantages of high accuracy and low cost. Experimental and theoretical investigations confirm its pH responsiveness and demonstrate its good sensitivity and reliability. By monitoring the total volatile basic nitrogen, this TTI can accurately predict food spoilage and can be adaptively modified for different types of food. The TTI based on this nanosensor enables visual monitoring of food quality.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Fangju Chen, Xueting Wang, Wei Chen, Chenwen Shao, Yong Qian
Summary: Lung cancer is the second most common malignant tumor worldwide. Drug resistance in lung cancer leads to treatment failure and recurrence in majority of patients. This study developed a fluorescent prodrug that can be activated in cancer cells to release drugs, and its signal can be tracked by imaging. It shows a unique autophagy-driven ferroptosis effect, indicating its potential for targeting drug-resistant cancer cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Weichao Li, Qiming Yuan, Zhangcheng Xia, Xiaoxue Ma, Lifang He, Ling Jin, Xiangfeng Chu, Kui Zhang
Summary: This study developed a high-performance gas sensor for formaldehyde detection by modifying ZnSnO3 with ZnO QDs and SnO2 QDs. The modified sensor showed improved sensing response and lower working temperature. The presence of ZnO QDs formed rich heterojunctions, increased surface area, and provided oxygen deficiency for formaldehyde sensing reaction, thus enhancing the sensor performance. This research provides an alternative method to enhance the sensing properties of MOS by QDs modification.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Joung-Il Moon, Eun Jung Choi, Younju Joung, Jin-Woo Oh, Sang-Woo Joo, Jaebum Choo
Summary: A novel nanoplasmonic substrate was developed for biomedical applications, which showed strong hot spots for detecting biomarkers at low concentrations. The substrate, called AuNPs@M13, was made by immobilizing 60 nm gold nanoparticles onto the surface of an M13 bacteriophage scaffold. It demonstrated higher sensitivity and lower limit of detection compared to commercially available assays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ning Li, Ya Zhang, Ying Xu, Xiaofang Liu, Jian Chen, Mei Yang, Changjun Hou, Danqun Huo
Summary: The molecular subtype of breast cancer guides treatment and drug selection. Invasive tests can promote cancer cell metastasis, so the development of high-performance, low-cost diagnostic tools for cancer prognosis is crucial. Liquid biopsy techniques enable noninvasive, real-time, dynamic, multicomponent, quantitative, and long-term observations at the cellular, genetic, and molecular levels. A Cu-Zr metal-organic framework (MOF) nanoenzyme with monatomic Cu attachment has been synthesized and proven to have high catalytic performance. The sensor constructed using this nanoenzyme shows potential for accurate classification of breast cancer serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Jeongmin Kim, Hyemin Kim, Seunghyun Park, Hyeonaug Hong, Yong Jae Kim, Jiyong Lee, Jaeho Kim, Seung-Woo Cho, Wonhyoung Ryu
Summary: This study presents a method to fabricate independently functioning microneedle (MN) electrodes with narrow intervals for high precision electrochemical sensing. The optimized mixture of photocurable polymer and single-wall carbon nanotubes was used to mold single composite MNs, which were then attached to pre-patterned electrodes. Plasma etching and electropolymerization were performed to enhance the electrochemical activity, and Prussian blue and glucose oxidase were electrodeposited on the MNs for glucose detection. The MN electrodes showed good sensitivity and linearity, and the feasibility of glucose detection was demonstrated in an in vivo mouse study.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
