Article
Multidisciplinary Sciences
Rasheid Smith, Emad Wafa, Sean M. Geary, Kareem Ebeid, Suhaila O. Alhaj-Suliman, Aliasger K. Salem
Summary: Nanoscale formulations can enhance the efficacy of cancer vaccines by combating the immunosuppressive nature of the tumor microenvironment. A newly synthesized nanoparticulate formulation demonstrated adjuvant properties in vivo, leading to increased TAA-specific T cells, reduced tumor burden, protection against tumor rechallenge, and improved median survival in tumor-challenged mice.
Article
Pharmacology & Pharmacy
Zhe Chen, Chaoyang Meng, Junhua Mai, Yongbin Liu, Hangwen Li, Haifa Shen
Summary: This study demonstrates that a lipid-formulated RNA vaccine composed of a protamine/mRNA core and a lipid shell is highly effective in promoting cytotoxic CD8 T cell responses and mediating anti-tumor immunity. Both the mRNA core and lipid shell are necessary for stimulating the expression of type I interferons and inflammatory cytokines in dendritic cells. The expression of interferon relies exclusively on STING, and the antitumor activity of the mRNA vaccine is compromised in mice with a defective Sting gene. Thus, the mRNA vaccine induces STING-dependent antitumor immunity.
ACTA PHARMACEUTICA SINICA B
(2023)
Article
Chemistry, Multidisciplinary
Eiji Yuba, Yuna Kado, Nozomi Kasho, Atsushi Harada
Summary: Introducing cationic lipids and using pH-responsive polysaccharides with intrinsic adjuvant function can improve the cellular association of liposomes with dendritic cells and increase cytokine production. These liposomes can promote tumor suppression by improving intra-tumoral immunosuppression and inducing antigen-specific cellular immunity.
JOURNAL OF CONTROLLED RELEASE
(2023)
Article
Nanoscience & Nanotechnology
Xuhan Liu, Yifan Liu, Xiaoyu Yang, Xinyu Lu, Xiao-Ning Xu, Jiancheng Zhang, Rongjun Chen
Summary: A novel polymer adjuvant has been reported for hepatitis B vaccine, which forms stable nanoformulations and shows good biocompatibility and cellular uptake ability. It also has the advantage of sparing antigen dosage.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Immunology
Zijun Wang, Pengcheng Zhou, Frauke Muecksch, Alice Cho, Tarek Ben Tanfous, Marie Canis, Leander Witte, Brianna Johnson, Raphael Raspe, Fabian Schmidt, Eva Bednarski, Justin Da Silva, Victor Ramos, Shuai Zong, Martina Turroja, Katrina G. Millard, Kai-Hui Yao, Irina Shimeliovich, Juan Dizon, Anna Kaczynska, Mila Jankovic, Anna Gazumyan, Thiago Y. Oliveira, Marina Caskey, Christian Gaebler, Paul D. Bieniasz, Theodora Hatziioannou, Michel C. Nussenzweig
Summary: Wang et al. analyze memory B cell and antibody responses in SARS-CoV-2 mRNA vaccines to breakthrough infections with Delta or Omicron BA.1 variants. They found that a third exposure to Delta increases strain-specific memory responses and overall potency and breadth of memory B cells, while a fourth exposure to Omicron BA.1 only increases strain-specific memory responses.
JOURNAL OF EXPERIMENTAL MEDICINE
(2022)
Article
Biochemistry & Molecular Biology
Rui Tada, Emi Honjo, Shoko Muto, Noriko Takayama, Hiroshi Kiyono, Jun Kunisawa, Yoichi Negishi
Summary: Mucosal vaccines have advantages over conventional parenteral vaccines, but few have been developed. This study found that intranasal administration of CpG ODN-loaded cationic liposomes can induce IL-6 release in nasal tissues, which promotes antigen-specific IgA responses.
Article
Immunology
Rui Tada, Akira Hidaka, Yuya Tanazawa, Akari Ohmi, Shoko Muto, Miki Ogasawara, Momoko Saito, Akihiro Ohshima, Naoko Iwase, Emi Honjo, Hiroshi Kiyono, Jun Kunisawa, Yoichi Negishi
Summary: The study demonstrates that intranasal administration of cationic liposomes can induce interleukin-6 (IL-6) expression at the administration site, promoting the production of IL-6 in nasal passages and splenocytes in mice. IL-6, produced by the nasally administered cationic liposomes, plays a crucial role in inducing antigen-specific IgA responses.
INTERNATIONAL IMMUNOPHARMACOLOGY
(2021)
Article
Biotechnology & Applied Microbiology
Ji-Xiang Jia, Sen-Lin Peng, Ndayambaje Yvan Kalisa, Qiang Chao, Zhifang Zhou, Xiao-Dong Gao, Ning Wang
Summary: In this study, a liposome-based vaccine platform carrying a carbohydrate antigen was optimized to improve stability and immunogenicity. The results showed that the reformulated liposomal vaccine induced a stronger immune response and successfully induced antibody class switching to IgG. Further analysis revealed that the elicited IgG antibodies specifically bound to tetrasaccharide biomarkers, mainly of the IgG2b isotype. These findings suggest that the liposome vaccine has great potential as a platform for the development of rapid diagnostic methods for ALG1-CDG and PMM2-CDG.
JOURNAL OF NANOBIOTECHNOLOGY
(2023)
Article
Pharmacology & Pharmacy
Long Xi, Zibei Lin, Fen Qiu, Shaokui Chen, Ping Li, Xin Chen, Zhenping Wang, Ying Zheng
Summary: This study demonstrates the effectiveness of celastrol-loaded mannose-modified liposomes (CEL-MAN-LPs) in the treatment of psoriasis. The results show that these modified liposomes enhance dendritic cell uptake and inhibit the expression of maturation markers. Intradermal injection of CEL-MAN-LPs significantly improves psoriasis symptoms compared to free drug or unmodified liposomes.
ACTA PHARMACEUTICA SINICA B
(2022)
Article
Immunology
Emil Joseph Vergara, Andy Cano Tran, Mi-Young Kim, Tufaria Mussa, Matthew J. Paul, Thomas Harrison, Rajko Reljic
Summary: Tuberculosis is a major global health threat with a quarter of the global population harboring latent TB. A study found that intranasal administration of spore and nanoparticle-based subunit vaccines can enhance and alter lung and systemic immune responses. Additionally, individuals with latent TB in the TB-endemic country of Mozambique showed stronger CD4 T cell reactivity to the vaccine candidate.
FRONTIERS IN IMMUNOLOGY
(2023)
Review
Immunology
Alberto Cagigi, Karin Lore
Summary: In this concise review, the concepts behind mRNA vaccination, the innate and adaptive immune response generated by mRNA vaccines in different animal models and in humans, examples of viral infections where mRNA vaccines have shown to induce potent responses, and the recent SARS-CoV-2 mRNA vaccine trials in humans are summarized.
Article
Medicine, Research & Experimental
Juan Sebastian Pappalardo, Stefano Salmaso, Tatyana S. Levchenko, Francesca Mastrotto, Sara Bersani, Cecilia A. Langellotti, Monica Vermeulen, Federica Ghersa, Valeria Quattrocchi, Patricia Zamorano, William C. Hartner, Micaela Toniutti, Tiziana Musacchio, Vladimir P. Torchilin
Summary: Dendritic cells are the main immune cells that trigger the immune response. A nanovaccine platform targeting dendritic cells has been developed based on the alpha 1',2-mannobiose derivative. The platform has shown enhanced immunogenicity in vivo, specific targeting in vitro, and non-specific avidity for various species, highlighting its potential for developing new vaccines.
MOLECULAR PHARMACEUTICS
(2021)
Article
Chemistry, Multidisciplinary
Vajiheh Jahani, Mona Yazdani, Ali Badiee, Mahmoud Reza Jaafari, Leila Arabi
Summary: The immunosuppressive tumor microenvironment limits the efficacy of cancer vaccines. Combining liposomal celecoxib with DC vaccines can normalize the tumor microenvironment and enhance the antitumor response.
JOURNAL OF CONTROLLED RELEASE
(2023)
Review
Immunology
Hongmin Kim, Sung Jae Shin
Summary: Dendritic cells play a crucial role in tuberculosis infection by interacting with immune cells and Mycobacterium tuberculosis, enhancing or inhibiting host defense mechanisms. Understanding the immune responses initiated by dendritic cells is essential for developing anti-tuberculosis control measures.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Article
Pharmacology & Pharmacy
Masood Alam Khan, Ajamaluddin Malik, Abdulmohsen M. Alruwetei, Mohammad A. Alzohairy, Bader Y. Alhatlani, Osamah Al Rugaie, Fahad A. Alhumaydhi, Arif Khan
Summary: In this study, the immune response of α-GalCer-Lip-MERS-CoV PLpro as a vaccine formulation was investigated using mouse models. The results showed that this formulation induced higher levels of antigen-specific antibodies, switching to a more antiviral IgG2a subclass, and increased lymphocyte proliferation. In addition, splenocytes from immunized mice secreted more cytokines. These findings suggest that α-GalCer-Lip-MERS-CoV PLpro may be a promising vaccine formulation for protecting against MERS-CoV infection.
JOURNAL OF DRUG TARGETING
(2022)
Article
Chemistry, Multidisciplinary
Lanlan Liu, Huamei He, Zhenyu Luo, Haimei Zhou, Ruijing Liang, Hong Pan, Yifan Ma, Lintao Cai
ADVANCED FUNCTIONAL MATERIALS
(2020)
Article
Engineering, Biomedical
Haimei Zhou, Huamei He, Ruijing Liang, Hong Pan, Ze Chen, Guanjun Deng, Shengping Zhang, Yifan Ma, Lanlan Liu, Lintao Cai
Summary: The study utilized slow-release Poly I: C-encapsulated nanoparticles and biomimetic system MPLP to effectively inhibit tumor growth and metastasis by activating bone marrow-derived macrophages' tumor-specific immune response.
Review
Chemistry, Multidisciplinary
Hong Pan, Mingbin Zheng, Aiqing Ma, Lanlan Liu, Lintao Cai
Summary: Many clinical trials for cancer precision medicine research are constrained by drug resistance, side effects, and low efficacy. However, utilizing cell/bacteria-derived materials with unique bioactive properties may offer promising tools for personalized therapy in cancer by precisely targeting tumors and modulating immune microenvironments effectively.
ADVANCED MATERIALS
(2021)
Correction
Nanoscience & Nanotechnology
Chuangjun Liu, Lihua Zhou, Fangfang Wei, Ling Li, Shunan Zhao, Ping Gong, Lintao Cai, Keith Man-Chung Wong
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Chemistry, Multidisciplinary
Xing Yang, Ting Yang, Qiqi Liu, Xiuwen Zhang, Xinghua Yu, Ryan T. K. Kwok, Luo Hai, Pengfei Zhang, Ben Zhong Tang, Lintao Cai, Ping Gong
Summary: In this study, biomimetic aggregation-induced emission (AIE) photothermal agents with hitchhiking ability (DC@BPBBT dots) were developed by coating the nanoaggregates of the NIR AIE polymeric photothermal agents with dendritic cell (DC) membranes. The DC@BPBBT dots can be hitchhiked on endogenous T cells, leading to enhanced tumor delivery efficiency. Additionally, these dots were found to activate T cells to secrete TNF-alpha, effectively reducing the expression of HSP70 and rendering tumor cells more sensitive to heat.
ADVANCED FUNCTIONAL MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Gongcheng Ma, Zhongke Liu, Chunguang Zhu, Huajie Chen, Ryan T. K. Kwok, Pengfei Zhang, Ben Zhong Tang, Lintao Cai, Ping Gong
Summary: Low-temperature photothermal therapy (PTT) is a promising therapeutic strategy, but the expression of heat shock proteins (HSPs) can hinder its efficacy. Researchers have developed a smart nanobomb that can explode in the tumor microenvironment and release carbon monoxide (CO) to inhibit the expression of HSPs, thereby improving the effectiveness of low-temperature PTT.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Analytical
Jingjing Xiang, Chunbai Xiang, Lihua Zhou, Mengsi Sun, Lixiong Feng, Chuangjun Liu, Lintao Cai, Ping Gong
Summary: In this study, a rational design strategy for A beta 42 fluorescence probes based on rhodamine-copper complexes was reported. The results showed that the Rho4-Cu probe exhibited high sensitivity, high affinity, and high selectivity, and was able to effectively differentiate normal mice and AD mice.
ANALYTICAL CHEMISTRY
(2022)
Review
Nanoscience & Nanotechnology
Yuhan Wang, Guojun Huang, Qi Hou, Hong Pan, Lintao Cai
Summary: Cell nanomodification is a reliable and efficient strategy that combines cell activity with nanomaterials to achieve remarkable treatment results.
WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY
(2023)
Review
Chemistry, Physical
Guojun Huang, Lanlan Liu, Hong Pan, Lintao Cai
Summary: This review summarizes the recent advances in using biomimetic active materials to guide immunogenic cell death (ICD) for cancer immunotherapy. It introduces two main strategies, including naive organism-derived nanoagents and engineered bioactive platforms. The challenges and future developments of using biomimetic active materials guided ICD in cancer immunotherapy applications are also discussed.
Article
Chemistry, Multidisciplinary
Lishan Zhang, Baozhen Zhang, Ruijing Liang, Hui Ran, Denghui Zhu, Jian Ren, Lanlan Liu, Aiqing Ma, Lintao Cai
Summary: A self-driving yeast micro/nanorobot (Cur@ CaY-robot) is designed via dual biomineralization and acid catalysis, which demonstrates efficient motion in gastric acid and can penetrate the thick gastric mucus for improved drug accumulation in the stomach wall tissue. Additionally, the released Ca2+ cations from the robot synergistically repair the gastric motility of gastritis mice. The biocompatible and biodegradable nature of these yeast micro/nanorobots, along with their good drug loading capacity, make them promising for active drug delivery and precise therapy.
Article
Multidisciplinary Sciences
Baozhen Zhang, Hong Pan, Ze Chen, Ting Yin, Mingbin Zheng, Lintao Cai
Summary: A twin-bioengine yeast micro/nanorobot (TBY-robot) with self-propelling and self-adaptive capabilities has been developed for targeted gastrointestinal inflammation therapy. The TBY-robot uses an enzyme-macrophage switching mechanism to autonomously navigate to inflamed sites. It successfully overcomes barriers in the gastrointestinal tract and enhances drug accumulation at the diseased site, demonstrating its potential for precision treatment of inflammatory diseases.
Article
Chemistry, Multidisciplinary
Zhiwei Zhang, Jingjing Xiang, Lijiao Guan, Pu Chen, Changzhong Li, Chunlei Guo, Yan Hu, Saipeng Huang, Lintao Cai, Ping Gong
Summary: By designing and synthesizing a pH-activated photothermal sensitizer IR-PE, it is possible to trigger the lysosomal dysfunction-mediated Fenton pathway under near-infrared light irradiation, thereby inducing ferroptosis and improving antitumor efficacy while mitigating systemic side effects.
Article
Chemistry, Multidisciplinary
Zhihong Sun, Zhuokai Sun, Jie Liu, Xiaohan Gao, Liping Jiao, Qi Zhao, Yongli Chu, Xiaozhong Wang, Guanjun Deng, Lintao Cai
Summary: This study presents a strategy that combines photodynamic therapy (PDT), immune checkpoints, and EV antigens to greatly improve the efficiency of tumor immunotherapy and overcome immune escape by improving the tumor immunosuppressive microenvironment.
Article
Chemistry, Multidisciplinary
Daoyong Jiang, Xiuwen Zhang, Yizhao Chen, Pengfei Zhang, Ping Gong, Lintao Cai, Yong Wang
Summary: A novel fluorescent probe, PM, was successfully synthesized and designed for the colorimetric fluorescent detection of Hg2+ in aqueous THF solution. The sensing mechanism of PM involves the metal ion-induced hydrolysis of the Schiff-base skeleton, which was confirmed by various experiments and calculations. A portable smartphone-assisted platform was established for the convenient and reliable Hg2+ detection. PM was also applied to monitor intracellular Hg2+ ions and has the potential for developing specific chemoprobes for Hg2+ detection in sulfur-rich living organisms.
NEW JOURNAL OF CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Chunbai Xiang, Musa Dirak, Yuan Luo, Yonglin Peng, Lintao Cai, Ping Gong, Pengfei Zhang, Safacan Kolemen
Summary: Acetylcholinesterase (AChE) is an important enzyme involved in various physiological and pathological processes. This study introduces a novel fluorescent probe with aggregation-induced emission (AIE) characteristics for selective and sensitive real-time imaging of AChE activity in vivo. The probe showed a selective turn-on fluorescence response to AChE with low detection limit and was successfully used to visualize AChE activity in glioblastoma cells, Alzheimer's disease mouse brain tissue, and living mouse brains.
MATERIALS CHEMISTRY FRONTIERS
(2022)
Article
Chemistry, Multidisciplinary
Laetitia Bardet, Herve Roussel, Stefano Saroglia, Masoud Akbari, David Munoz-Rojas, Carmen Jimenez, Aurore Denneulin, Daniel Bellet
Summary: The thermal instability of silver nanowires leads to increased electrical resistance in AgNW networks. Understanding the relationship between structural and electrical properties of AgNW networks is crucial for their integration as transparent electrodes in flexible optoelectronics. In situ X-ray diffraction measurements were used to study the crystallographic evolution of Ag-specific Bragg peaks during thermal ramping, revealing differences in thermal and structural transitions between bare and SnO2-coated AgNW networks.
Article
Chemistry, Multidisciplinary
Nathalia Cancino-Fuentes, Arnau Manasanch, Joana Covelo, Alex Suarez-Perez, Enrique Fernandez, Stratis Matsoukis, Christoph Guger, Xavi Illa, Anton Guimera-Brunet, Maria V. Sanchez-Vives
Summary: This study provides a comprehensive characterization of graphene-based solution-gated field-effect transistors (gSGFETs) for brain recordings, highlighting their potential clinical applications.
Article
Chemistry, Multidisciplinary
Sikandar Aftab, Hailiang Liu, Dhanasekaran Vikraman, Sajjad Hussain, Jungwon Kang, Abdullah A. Al-Kahtani
Summary: This study examines the effects of hybrid nanoparticles made of NiO@rGO and NiO@CNT on the active layers of polymer solar cells and X-ray photodetectors. The findings show that these hybrid nanoparticles can enhance the charge carrier capacities and exciton dissociation properties of the active layers. Among the tested configurations, the NiO@CNT device demonstrates superior performance in converting sunlight into electricity, and achieves the best sensitivity for X-ray detection.
Article
Chemistry, Multidisciplinary
Hyo Jung Shin, Seung Gyu Choi, Fengrui Qu, Min-Hee Yi, Choong-Hyun Lee, Sang Ryong Kim, Hyeong-Geug Kim, Jaewon Beom, Yoonyoung Yi, Do Kyung Kim, Eun-Hye Joe, Hee-Jung Song, Yonghyun Kim, Dong Woon Kim
Summary: This study investigates the role of SOX9 in reactive astrocytes following ischemic brain damage using a PLGA nanoparticle plasmid delivery system. The results demonstrate that PLGA nanoparticles can reduce ischemia-induced neurological deficits and infarct volume, providing a potential opportunity for stroke treatment.
Article
Chemistry, Multidisciplinary
Anurag Chaudhury, Koushik Debnath, Nikhil R. Jana, Jaydeep K. Basu
Summary: The study investigates the interaction between nanoparticles and cell membranes, and identifies key parameters, including charge, crowding, and membrane fluidity, that determine the adsorbed concentration and unbinding transition of nanoparticles.
Article
Chemistry, Multidisciplinary
Sina Sadeghi, Fazel Bateni, Taekhoon Kim, Dae Yong Son, Jeffrey A. Bennett, Negin Orouji, Venkat S. Punati, Christine Stark, Teagan D. Cerra, Rami Awad, Fernando Delgado-Licona, Jinge Xu, Nikolai Mukhin, Hannah Dickerson, Kristofer G. Reyes, Milad Abolhasani
Summary: In this study, an autonomous approach for the development of lead-free metal halide perovskite nanocrystals is presented, which integrates a modular microfluidic platform with machine learning-assisted synthesis modeling. This approach enables rapid and optimized synthesis of copper-based lead-free nanocrystals.
Article
Chemistry, Multidisciplinary
Zahir Abbas, Nissar Hussain, Surender Kumar, Shaikh M. Mobin
Summary: The rational construction of free-standing and flexible electrodes for electrochemical energy storage devices is an emerging research focus. In this study, a redox-active metal-organic framework (MOF) was prepared on carbon nanofibers using an in situ approach, resulting in a flexible electrode with high redox-active behavior and unique properties such as high flexibility and lightweight. The prepared electrode showed excellent cyclic retention and rate capability in supercapacitor applications. Additionally, it could be used as a freestanding electrode in flexible devices at different bending angles.
Article
Chemistry, Multidisciplinary
Lishan Zhang, Xiaoting Zhang, Hui Ran, Ze Chen, Yicheng Ye, Jiamiao Jiang, Ziwei Hu, Miral Azechi, Fei Peng, Hao Tian, Zhili Xu, Yingfeng Tu
Summary: Photodynamic therapy (PDT) is a promising local treatment modality in cancer therapy, but its therapeutic efficacy is restricted by ineffective delivery of photosensitizers and tumor hypoxia. In this study, a phototactic Chlorella-based near-infrared (NIR) driven green affording-oxygen microrobot system was developed for enhanced PDT. The system exhibited desirable phototaxis and continuous oxygen generation, leading to the inhibition of tumor growth in mice. This study demonstrates the potential of using a light-driven green affording-oxygen microrobot to enhance photodynamic therapy.
Article
Chemistry, Multidisciplinary
Yujin Li, Jing Xu, Xinqi Luo, Futing Wang, Zhong Dong, Ke-Jing Huang, Chengjie Hu, Mengyi Hou, Ren Cai
Summary: In this study, hollow heterostructured materials were constructed using an innovative template-engaged method as cathodes for zinc-ion batteries. The materials exhibited fast Zn2+ transport channels, improved electrical conductivity, and controlled volume expansion during cycling. The designed structure allowed for an admirable reversible capacity and high coulombic efficiency.
Article
Chemistry, Multidisciplinary
Paritosh Mahato, Shashi Shekhar, Rahul Yadav, Saptarshi Mukherjee
Summary: This study comprehensively elucidates the role of the core and electrostatic surface of metal nanoclusters in catalytic reduction reactions. The electrostatic surface dramatically modulates the reactivity of metal nanoclusters.
Article
Chemistry, Multidisciplinary
Pei Liu, Mengdi Liang, Zhengwei Liu, Haiyu Long, Han Cheng, Jiahe Su, Zhongbiao Tan, Xuewen He, Min Sun, Xiangqian Li, Shuai He
Summary: This study demonstrates a simple and environmentally-friendly method for the synthesis of zinc oxide nanozymes (ZnO NZs) using wasted hop extract (WHE). The WHE-ZnO NZs exhibit exceptional peroxidase-like activity and serve as effective catalysts for the oxidation of 3,3,5,5-tetramethylbenzidine (TMB) in the presence of hydrogen peroxide (H2O2). In addition, a straightforward colorimetric technique for detecting both H2O2 and glucose was developed using the WHE-ZnO NZs as peroxidase-like catalysts.
Article
Chemistry, Multidisciplinary
Hyunkyu Oh, Young Jun Lee, Eun Ji Kim, Jinseok Park, Hee-Eun Kim, Hyunsoo Lee, Hyunjoo Lee, Bumjoon J. Kim
Summary: Mesoporous carbon particles have unique structural properties that make them suitable as support materials for catalytic applications. This study investigates the impact of channel nanostructures on the catalytic activity of porous carbon particles (PCPs) by fabricating PCPs with controlled channel exposure on the carbon surface. The results show that PCPs with highly open channel nanostructures exhibit significantly higher catalytic activity compared to those with closed channel nanostructures.
Article
Chemistry, Multidisciplinary
Yunjie Lu, Zhaohui Li, Zewei Li, Shihao Zhou, Ning Zhang, Jianming Zhang, Lu Zong
Summary: A tough, long-lasting adhesive and highly conductive nanocomposite hydrogel (PACPH) was fabricated via the synergy of interfacial entanglement and adhesion group densification. PACPH possesses excellent mechanical properties, interfacial adhesion strength, and conductivity, making it a promising material for long-term monitoring of human activities and electrocardiogram signals.
Article
Chemistry, Multidisciplinary
Zichao Wei, Audrey Vandergriff, Chung-Hao Liu, Maham Liaqat, Mu-Ping Nieh, Yu Lei, Jie He
Summary: We have developed a simple method to prepare polymer-grafted plasmonic metal nanoparticles with pH-responsive surface-enhanced Raman scattering. By using pH-responsive polymers as ligands, the aggregation of nanoparticles can be controlled, leading to enhanced SERS. The pH-responsive polymer-grafted nanoparticles show high reproducibility and sensitivity in solution, providing a novel approach for SERS without the need for sample pre-concentration.
Article
Chemistry, Multidisciplinary
Melis Ozge Alas Colak, Ahmet Gungor, Merve Buldu Akturk, Emre Erdem, Rukan Genc
Summary: This research investigates the effect of functionalizing carbon dots with hydroxyl polymers on their performance as electrode materials in a supercapacitor. The results show that the functionalized carbon dots exhibit excellent electrochemical performance and improved stability.