Nanoengineering approaches to the design of artificial antigen-presenting cells

Selection of perforin expressing CD4+ adenovirus-specific T-cells with artificial antigen presenting cells

(2013) Lianne M. Haveman et al.   CLINICAL IMMUNOLOGY

Particle shape enhances specificity of antibody-displaying nanoparticles

(2013) Sutapa Barua et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Receptor Signaling Clusters in the Immune Synapse

(2012) Michael L. Dustin et al.   Annual Review of Biophysics

Fabrication of Binary and Ternary Hybrid Particles Based on Colloidal Lithography

(2012) Ye Yu et al.   CHEMISTRY OF MATERIALS

A stepwise protocol to coat aAPC beads prevents out-competition of anti-CD3 mAb and consequent experimental artefacts

(2012) Silvia A. Fuertes Marraco et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Connecting the Dots: Artificial Antigen Presenting Cell-Mediated Modulation of Natural Killer T Cells

(2012) Wenji Sun et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Lipid-enveloped hybrid nanoparticles for drug delivery

(2012) Songwei Tan et al.   Nanoscale

Synthetic nanoparticles functionalized with biomimetic leukocyte membranes possess cell-like functions

(2012) Alessandro Parodi et al.   Nature Nanotechnology

Raising the Bar: The Curative Potential of Human Cancer Immunotherapy

(2012) S. A. Rosenberg   Science Translational Medicine

Patchy, Anisotropic Microspheres with Soft Protein Islets

(2011) Kaladhar Kamalasanan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A novel system of artificial antigen-presenting cells efficiently stimulates Flu peptide-specific cytotoxic T cells in vitro

(2011) Hui Han et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

An Artificial Antigen-presenting Cell with Paracrine Delivery of IL-2 Impacts the Magnitude and Direction of the T Cell Response

(2011) Erin R. Steenblock et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The targeted delivery of multicomponent cargos to cancer cells by nanoporous particle-supported lipid bilayers

(2011) Carlee E. Ashley et al.   NATURE MATERIALS

Synthetic Protocells Interact with Viral Nanomachinery and Inactivate Pathogenic Human Virus

(2011) Matteo Porotto et al.   PLoS One

Using mechanobiological mimicry of red blood cells to extend circulation times of hydrogel microparticles

(2011) T. J. Merkel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Erythrocyte membrane-camouflaged polymeric nanoparticles as a biomimetic delivery platform

(2011) C.-M. J. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Artificial Antigen-Presenting Cells for Use in Adoptive Immunotherapy

(2010) Cameron J. Turtle et al.   CANCER JOURNAL

Killer artificial antigen-presenting cells: the synthetic embodiment of a ‘guided missile’

(2010) Christian Schütz et al.   Immunotherapy

Polymer particle shape independently influences binding and internalization by macrophages

(2010) Gaurav Sharma et al.   JOURNAL OF CONTROLLED RELEASE

Generation of a Library of Particles Having Controlled Sizes and Shapes via the Mechanical Elongation of Master Templates

(2010) Yapei Wang et al.   LANGMUIR

Macromol. Rapid Commun. 2/2010

(2010) Amar B. Pawar et al.   MACROMOLECULAR RAPID COMMUNICATIONS

Cell mechanics and the cytoskeleton

(2010) Daniel A. Fletcher et al.   NATURE

Sipuleucel-T Immunotherapy for Castration-Resistant Prostate Cancer

(2010) Philip W. Kantoff et al.   NEW ENGLAND JOURNAL OF MEDICINE

Polymer particles that switch shape in response to a stimulus

(2010) J.-W. Yoo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamic regulation of functionally distinct virus-specific T cells

(2010) Zaza M. Ndhlovu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lipid Rafts As a Membrane-Organizing Principle

(2010) D. Lingwood et al.   SCIENCE

In vivo Administration of Artificial Antigen-Presenting Cells Activates Low-Avidity T Cells for Treatment of Cancer

(2009) S. Ugel et al.   CANCER RESEARCH

Ex vivo induction and expansion of natural killer T cells by CD1d1-Ig coated artificial antigen presenting cells

(2009) Tonya J. Webb et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Human CD1 dimeric proteins as indispensable tools for research on CD1-binding lipids and CD1-restricted T cells

(2009) Takayuki Shiratsuchi et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Electrostatically Mediated Liposome Fusion and Lipid Exchange with a Nanoparticle-Supported Bilayer for Control of Surface Charge, Drug Containment, and Delivery

(2009) Juewen Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Multifunctional Patchy Particles by Glancing Angle Deposition

(2009) Amar B. Pawar et al.   LANGMUIR

Scalable, Shape-Specific, Top-Down Fabrication Methods for the Synthesis of Engineered Colloidal Particles

(2009) Timothy J. Merkel et al.   LANGMUIR

Clustering of Stimuli on Single-Walled Carbon Nanotube Bundles Enhances Cellular Activation

(2009) Tarek R. Fadel et al.   LANGMUIR

Polymeric Materials for Gene Delivery and DNA Vaccination

(2008) David N. Nguyen et al.   ADVANCED MATERIALS

In vivo functional efficacy of tumor-specific T cells expanded using HLA-Ig based artificial antigen presenting cells (aAPC)

(2008) Malarvizhi Durai et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Microfluidic-Assisted Synthesis of Polymer Particles

(2008) C. A. Serra et al.   CHEMICAL ENGINEERING & TECHNOLOGY

Nanoparticles target distinct dendritic cell populations according to their size

(2008) Vania Manolova et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The effect of artificial antigen-presenting cells with preclustered anti-CD28/-CD3/-LFA-1 monoclonal antibodies on the induction of ex vivo expansion of functional human antitumor T cells

(2008) R. Zappasodi et al.   HAEMATOLOGICA

Shape-Specific, Monodisperse Nano-Molding of Protein Particles

(2008) Jennifer Y. Kelly et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Control of Endothelial Targeting and Intracellular Delivery of Therapeutic Enzymes by Modulating the Size and Shape of ICAM-1-targeted Carriers

(2008) Silvia Muro et al.   MOLECULAR THERAPY

A Comprehensive Platform for Ex Vivo T-cell Expansion Based on Biodegradable Polymeric Artificial Antigen-presenting Cells

(2008) Erin R Steenblock et al.   MOLECULAR THERAPY

Enhanced Cellular Activation with Single Walled Carbon Nanotube Bundles Presenting Antibody Stimuli

(2008) Tarek R. Fadel et al.   NANO LETTERS

Shape Induced Inhibition of Phagocytosis of Polymer Particles

(2008) Julie A. Champion et al.   PHARMACEUTICAL RESEARCH

Janus particles

(2008) Andreas Walther et al.   Soft Matter

Killer artificial antigen-presenting cells: a novel strategy to delete specific T cells

(2007) C. Schutz et al.   BLOOD