Article
Chemistry, Analytical
Jae-Hoon Hwang, David Fox, Jordan Stanberry, Vasileios Anagnostopoulos, Lei Zhai, Woo Hyoung Lee
Summary: The novel AuNP-biopolymer-coated carbon screen-printed electrode sensor showed successful detection of Hg2+ in landfill leachate, with good sensitivity, broad linear response range, low detection limit, and excellent selective response to Hg2+. It demonstrated stable peak current and low relative standard deviation, indicating excellent stability, sensitivity, reproducibility, and consistent performance in detecting the Hg2+ ion in landfill leachate, as well as reliability and performance in measuring heavy metals.
Article
Chemistry, Analytical
Ning Liu, Guo Zhao, Gang Liu
Summary: This study introduces a new method to detect Cd(II) and Pb(II) using feature stripping currents, which shows better anti-interference capability and detection accuracy. Models established using SVR and the partial least square algorithms demonstrate superior detection performance.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Guo Zhao, Thien-Toan Tran, Sidharth Modha, Mohammed Sedki, Nosang V. Myung, David Jassby, Ashok Mulchandani
Summary: This study presents multiplexed anodic stripping voltammetry detection of heavy metal ions using a homemade electrochemical cell with a 3D-printed flow cell. The sensor platform showed high selectivity and accuracy, with a potential applicability in complex matrices, achieving a 95-101% recovery rate in simulated river water.
FRONTIERS IN CHEMISTRY
(2022)
Article
Engineering, Electrical & Electronic
Dingnan Lu, Connor Sullivan, Eric M. Brack, Christopher P. Drew, Pradeep Kurup
Summary: The newly developed voltammetric approach shows excellent detection performance for trace mercury (II) and has practical significance for reliable prediction of mercury (II) concentration in complex media.
IEEE SENSORS JOURNAL
(2021)
Article
Engineering, Electrical & Electronic
Sai Snehitha Yadavalli, Bratati Sen, Swati Ghosh Acharyya
Summary: Gold nanoparticles (AuNPs) were synthesized using neem and hibiscus leaf extracts and characterized. The AuNPs synthesized from hibiscus leaf extract (HLE) showed greater stability than those from neem leaf extract (NLE). The HLE-synthesized AuNPs were successfully used for electrochemical sensing of heavy metal ions. Optimization of pH, deposition time, and deposition potential was carried out for individual and simultaneous detection of Cd+2, Pb2+, and As+3. The LOD for Cd+2, Pb2+, and As+3 ions using HLE-synthesized AuNPs were 8.59, 1.85, and 4.77 nM, respectively, for individual detection, and 11.92, 23.72, and 77.48 nM, respectively, for simultaneous detection.
IEEE SENSORS JOURNAL
(2023)
Article
Chemistry, Analytical
Heleni Panagopoulou, Anastasios Economou, Christos Kokkinos
Summary: This paper introduces a 3D-printed microfluidic device for the determination of Pb(II) and Cd(II) using SIA-ASV method. The device enables online preconcentration and static solution detection, achieving low detection limits and good repeatability.
ANALYTICA CHIMICA ACTA
(2021)
Article
Chemistry, Analytical
Ranjeet Kaur, Shweta Rana, Khushwinder Kaur, Navodita
Summary: This research presents a novel reverse micro-emulsification route to synthesize monodisperse palladium nanoparticles embedded RGO based nanoreactors (Pd@NrGO/GCE). The nanoreactors act as electrocatalysts for the oxidation of methylparathion, showing faster rates of redox reactions. Characterization of the nanoreactors was done using various techniques such as X-ray diffraction, Raman spectroscopy, SEM, SAXS, and HRTEM analysis. The sensor fabricated with these nanoreactors exhibited wide linearity and a low limit of detection of 1.067 ng/ml, with successful application in real-time analysis.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Rui Liu, Chao-Jun Zhang, Xue Han, Tian-Heng Wu, Ri-Jia Liu, Yuan Sun, Shuang Jin
Summary: Graphene-derived materials are used as excellent electrodes for detecting heavy metals. A MnO2/graphene supported on Ni foam electrode was prepared and used to detect Pb(II) in water. The electrode showed good stability, reproducibility, and a low limit of detection (0.2 mu M (S/N = 3)) for Pb(II). The excellent performance is attributed to the strong adhesion force between graphene and MnO2.
Article
Chemistry, Analytical
Martijn Eikelboom, Yaxuan Wang, Gemma Portlock, Arthur Gourain, Joseph Gardner, Jay Bullen, Paul Lewtas, Matthieu Carriere, Alexandra Alvarez, Arun Kumar, Shane O'Prey, Tamas Tolgyes, Dario Omanovic, Subhamoy Bhowmick, Dominik Weiss, Pascal Salaun
Summary: The voltammetric determination of total inorganic arsenic in near-neutral pH conditions using a new commercially available 25 μm diameter gold microwire was presented. The method has better analytical parameters than previous methods and is easier to implement, enabling cheaper groundwater surveying campaigns with in-the-field analysis for quick data reporting, even in remote communities.
ANALYTICA CHIMICA ACTA
(2023)
Article
Chemistry, Analytical
Lan Yang, Leilei Sun, Jie Song, Xueliang Zhao, Xicai Pan, Zeming Wu, Qingyun Cai
Summary: The motivation of this work is to develop a simple method for on-site detection of total arsenic at the ppb level. Novel nano-coral gold (NCG) was fabricated and used with square wave anodic stripping voltammetry (SWASV) to determine arsenic concentration in industrial water. The NCG working electrode achieved high sensitivity with a limit of detection (LOD) of 0.4 ppb. The detectable concentration is far below the regulatory limit set by WHO.
ANALYTICAL LETTERS
(2022)
Article
Chemistry, Analytical
Ma Lucia Abad-Gil, Ma Jesus Gismera, Teresa Sevilla, Jesus R. Procopio
Summary: In this study, the electrochemical behavior of MIT on a gold electrode was investigated and square wave voltammetric methods were developed for its determination at different concentration levels. MIT showed an irreversible and diffusion-controlled oxidation process, with pH-dependent potential and peak current values. By using square-wave voltammetry (SWV) and adsorptive stripping approach (SWAdSV), it is possible to determine MIT in water samples with high sensitivity and low detection limits. Both SWV and SWAdSV methods were successfully applied for the analysis of MIT in different water samples.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
Zhiwei Lu, Wenyuan Zhao, Lan Wu, Jie He, Wanlin Dai, Cailong Zhou, Haijun Du, Jianshan Ye
Summary: An effective strategy for the fabrication of novel layer-by-layer multilayer films modified electrodes in electrochemical sensor applications is proposed in this work. The newly constructed three-layer assembly of MWCNTs-COOH/UiO-66-NH2/MWCNTs-COOH/GCE as voltammetric sensor was adapted to simultaneous detection of Cd2+ and Pb2+. The combination of abundant adsorption sites of UiO-66-NH2 with excellent conductivity ability of MWCNTs-COOH, and the dominant characteristics of the chelation mechanisms between amine groups and heavy metal cations, strengthened its electrocatalytic activity.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Analytical
Mary-Lou Tercier-Waeber, Marianna Fighera, Melina Abdou, Eric Bakker, Peter van der Wal
Summary: This study developed a new gel-integrated nanostructured gold-based microelectrode array for direct detection of inorganic arsenite in fresh and marine aquatic systems. The sensors demonstrated sub-nanomolar detection and quantification limits, making them suitable for remote high-resolution monitoring underwater.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Analytical
Chyh Shyang Ong, Nurul Hanisarina binti Zaharum, Noorhashimah Mohamad Nor, Abdul Latif Ahmad, Qi Hwa Ng, Khairunisak Abdul Razak, Siew Chun Low
Summary: The sensitivity of screen-printed electrochemical sensors strongly depends on the selection of appropriate modifiers that optimize the chemical and physical properties of the sensor surface. This study investigated the impact of chemical and physical factors on the sensitivity of modified sensors for detecting lead and cadmium. The study found that metal-attracting functional groups and surface charge were the dominant factors affecting the sensitivity, while the physical morphology of the sensor surface had a minimal effect. The findings provide valuable insights for designing sensors for heavy metal detection.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
David Majer, Matjaz Finsgar
Summary: This study developed a non-enzymatic sensor for the determination of the organophosphorus pesticide methyl parathion. By optimizing the experimental conditions and utilizing the multiple standard addition methodology, the accuracy and precision of the detection method were significantly improved.
MICROCHEMICAL JOURNAL
(2022)
Article
Chemistry, Multidisciplinary
Jiaru Fang, Dongxin Xu, Hao Wang, Jin Wu, Ying Li, Tao Yang, Chuan Liu, Ning Hu
Summary: Electrophysiology is a unique biomarker for disease investigation or drug assessment in electrogenic cells. Vertical nanoelectrode arrays have been successful in achieving high-quality intracellular electrophysiological study in electrogenic cells. However, achieving high success rate and high-quality, long-term intracellular recording using inexpensive nanostructures remains a challenge. In this study, a scalable and robust hollow nanopillar electrode was developed to enhance intracellular recording of cardiomyocytes. Regulation of the nanostructure geometry proved to be a powerful strategy in enhancing intracellular recording.
Article
Chemistry, Analytical
Hao Wang, Quchao Zou, Yuting Xiang, Jinhu Yang, Zhongyuan Xu, Wenjian Yang, Yue Wu, Jin Wu, Dong Liu, Ning Hu, Diming Zhang
Summary: Researchers have developed a colorimetric plate reader based on smartphones and tablets, which has intelligent and dynamic light modulation capabilities. Compared to traditional plate readers and smartphone-based systems, this system exhibits higher sensitivity, lower detection limits, and broader detection ranges.
Article
Materials Science, Multidisciplinary
Min-Ya Yu, Yu-Ming Guan, Qixia Bai, Peiyang Su, Pingshan Wang, Ting-Zheng Xie
Summary: A new type of coordination-driven cuboctahedron cage was presented to study the fluorescent behavior of quantitatively confined aggregation-induced emission (AIE) molecules in a giant cavity. The cage, with 12 AIE molecules anchored endohedrally linked with different-length alkyl chains, exhibited strong fluorescence in highly diluted conditions. The fluorescence quantum yield could be altered by prolonging the length of alkyl chains. This study has great potential applications in biology mimic and fluorescent microscopes utilizing confined or isolated fluorescent methods.
ADVANCED OPTICAL MATERIALS
(2023)
Article
Chemistry, Inorganic & Nuclear
Guotao Wang, Qixia Bai, Hui Liu, Zhengguang Li, Zhiyuan Jiang, Zhe Zhang, Yiming Li, Pingshan Wang
Summary: We achieved the adjustable self-assembly of metallosupramolecular cages by utilizing the steric hindrance effect, which allows for the precise control of their shape and size.
INORGANIC CHEMISTRY
(2023)
Article
Chemistry, Inorganic & Nuclear
Qixia Bai, Zhiyuan Jiang, Yuming Guan, Qingwu Long, Bokai Liao, Ting-Zheng Xie, Tun Wu, Zhe Zhang, Pingshan Wang
Summary: In this study, a decametric metal-organic cage, pentagonal prism Mn20LC10, was developed based on Tpy-Mn(II)-Tpy connectivity, with Mn(II) serving as a linker to provide good photosensitivity. This metal-organic cage exhibited enhanced 1O2 production, fast conversion time, recyclability, and substrate versatility in the photooxidation of benzaldehyde due to improved intersystem crossing ability. Remarkably, the abundant active sites of Mn20LC10 enabled its photooxidation under solvent-free and daylight conditions. This work offers potential approaches for the development of inexpensive, green, and low-cost photosensitizer systems.
INORGANIC CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Jiaru Fang, Yuxiang Pan, Jiarong Xu, Dongxin Xu, Hongbo Li, Chuan Liu, Ning Hu
Summary: An integrated cardiomyocyte-based biosensing platform has been developed to record action potential and evaluate the quality of electroporation. This platform shows potential for drug delivery therapy and pathology research in cardiology.
Article
Multidisciplinary Sciences
Qiong Yang, Hongchao Ji, Zhenbo Xu, Yiming Li, Pingshan Wang, Jinyu Sun, Xiaqiong Fan, Hailiang Zhang, Hongmei Lu, Zhimin Zhang
Summary: This study proposes a fast and accurate spectrum matching method called FastEI, which improves the accuracy and speed of matching by using Word2vec spectral embedding and hierarchical navigable small-world graph. The study shows that FastEI achieves a speedup of two orders of magnitude compared with the commonly used weighted cosine similarity method and achieves high accuracy when identifying compounds using a million-scale in-silico library.
NATURE COMMUNICATIONS
(2023)
Article
Chemistry, Multidisciplinary
Kai Zhu, Tao Yan, Chunlian Qin, Yuxiang Pan, Jun Li, Hao Lai, Dongxin Xu, Chunsheng Wang, Ning Hu
Summary: This study presents the development of a three-dimensional cardiomyocyte-nanobiosensing system that can specifically recognize drug subgroups, providing an accurate and sensitive platform for drug screening in cardiovascular diseases.
Article
Chemistry, Analytical
Ning Hu, Hao Wan
Article
Chemistry, Multidisciplinary
Qixia Bai, Yu-Ming Guan, Tun Wu, Ying Liu, Zirui Zhai, Qingwu Long, Zhiyuan Jiang, Peiyang Su, Ting-Zheng Xie, Pingshan Wang, Zhe Zhang
Summary: We report a terpyridine-based metallo-cage that can undergo controlled hierarchical self-assembly of superstructures in response to different halide ions. By adding Cl-/Br- or I-, drastically different hierarchical superstructures with highly-tight hexagonal packing or graphite-like packing arrangements, respectively, have been achieved. These unusual halide-ion-triggered hierarchical structural changes provide new insights into the mechanism of supramolecular aggregation and crystal growth.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Nanoscience & Nanotechnology
Xingxing Liu, Dongxin Xu, Jiaru Fang, Yuheng Liao, Mingyue Zhang, Hongbo Li, Wenjian Yang, Yue Wu, Zhongyuan Xu, Ning Hu, Diming Zhang
Summary: With the development of micro/nanotechnologies, researchers have developed multielectrode arrays (MEAs) with different three-dimensional (3D) micro/nanostructures for intracellular action potential recording of cardiomyocytes. However, the effect of 3D micro/nanostructure density on intracellular recording has not been fully explored. In this study, 3D tunable nanodensity electrode arrays (TNDEA) were fabricated to investigate the impact of nanodensity regulation on intracellular biosensing. The low-nanodensity TNDEA achieved improved signal quality of intracellular potentials, including amplitude, signal-to-noise ratio (SNR), recording duration, and recording yield, compared to the high-nanodensity TNDEA. This 3D nanodensity regulating strategy has the potential to serve as a powerful electrophysiological research tool in the biomedical field.
Article
Chemistry, Inorganic & Nuclear
Wanying Zhong, Zhantao Wang, Wei-Dong Yu, Ning Wang, Fan Fu, Jun Wang, He Zhao, Die Liu, Zhilong Jiang, Pingshan Wang, Mingzhao Chen
Summary: In the field of metallo-supramolecular assemblies, supramolecular macrocycles with guest recognition and catalytic properties have attracted attention. This study presents a novel strategy for constructing giant hollow macrocyclic structures using a bi-directional geometric constraint strategy. By designing two terpyridine-based tetratopic organic ligands with different angles, the mutual interaction between the ligands promotes the formation of giant hollow macrocyclic supramolecular architectures. The self-assembly mechanism and hierarchical self-assembly of the giant supramolecular macrocycles are characterized by NMR, ESI-MS, and TEM experiments.
DALTON TRANSACTIONS
(2023)
Article
Chemistry, Inorganic & Nuclear
Kaixiu Li, Jian Huang, Shi-Cheng Wang, Zhengguang Li, Jun Wang, Yiming Li, Mingzhao Chen, Yi-Tsu Chan, Die Liu, Pingshan Wang
Summary: A terpyridine-based supramolecular cage was synthesized by the self-assembly of a hexapodal metal-organic ligand with Zn2+. The cage exhibited large parallel planes with a diameter close to 6 nm and a face-to-face distance close to 3.5 nm, and it possessed a large cavity. Various spectroscopic techniques and microscopy measurements supported the formation of the supramolecular cage. Furthermore, the corresponding metal-organic gel showed good adsorption performance for dye molecules.
DALTON TRANSACTIONS
(2023)
Article
Chemistry, Inorganic & Nuclear
Yu-Ming Guan, Qixia Bai, Zhe Zhang, Tun Wu, Ting-Zheng Xie, Pingshan Wang
Summary: In this study, a truncated triangular prism with D3h symmetry was successfully constructed using a ligand with both cis- and trans-configurations upon coordination with metal. This work provides new ideas and methods for the future synthesis of low-symmetry topological supramolecules.
DALTON TRANSACTIONS
(2023)
Review
Nanoscience & Nanotechnology
Yi Zhang, Ning Hu, Jiajie Xu, Zhen Wang
Summary: DNA programming, based on base complementary pairing and Boolean operations, has practical applications in multidisciplinary cutting-edge research. DNA logic circuits play a crucial role in biomedical fields, enabling autonomous assessment and stable visual signal outputs.
Article
Chemistry, Analytical
Mengmeng Guo, Na Luo, Yueling Bai, Zhenggang Xue, Qingmin Hu, Jiaqiang Xu
Summary: A porous heterostructure WO3-C/In2O3 was designed and prepared for a miniature H2 sensor, which showed higher response value, lower operating temperature, fast response-recovery speed, and low limit of detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Feng Hu, Hui Hu, Yuting Li, Xiaohui Wang, Xiaowen Shi
Summary: Arsenic contamination in water bodies is a significant health risk. This study developed a chitosan-catechol modified electrode for rapid and accurate detection of trace amounts of arsenic. The modified electrode demonstrated good detection capability and resistance to ionic interference, making it suitable for in situ detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yantao Zhang, Qian Liu, Tao Tian, Chunhua Xu, Pengli Yang, Lianju Ma, Yi Hou, Hui Zhou, Yongjun Gan
Summary: In this study, a lysosome-targeting buffering fluorogenic probe (Lyso-BFP) was designed and synthesized, demonstrating excellent photostability, pH specificity, and responsiveness to lysosomal acidification in living cells. The performance of Lyso-BFP in pH sensing was attributed to the inhibition of the photo-induced electron transfer process. Lyso-BFP allowed for wash-free imaging and long-term real-time monitoring of lysosome pH changes based on its off-on fluorescence behavior and buffer strategy.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Wei Cai, Wenbo Sun, Jiayue Wang, Xiaokui Huo, Xudong Cao, Xiangge Tian, Xiaochi Ma, Lei Feng
Summary: In this study, a near-infrared fluorescent probe HCBG was developed for imaging of alpha-GLC. HCBG exhibited excellent selectivity and sensitivity towards alpha-GLC in complex bio-samples, and showed good cell permeability for in situ real-time imaging. Through the high-throughput screening system established by HCBG, a natural alpha-GLC inhibitor was successfully isolated and identified. This study provides a novel fluorescence visualization tool for discovering and exploring the biological functions of diabetes-related gut microbiota, and a high-throughput screening approach for alpha-GLC inhibitor.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Trey W. Pittman, Xi Zhang, Chamindie Punyadeera, Charles S. Henry
Summary: Heart failure is a growing epidemic and a significant clinical and public health problem. Researchers have developed a portable and affordable diagnostic device for heart failure that can be used at the point-of-care, providing a valid alternative to current diagnostics approaches.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Anders O. Tjell, Barbara Jud, Roland Schaller-Ammann, Torsten Mayr
Summary: An optical hydrogen peroxide sensor based on catalytic degradation and the detection of produced oxygen is presented. The sensor offers higher resolution and better sensitivity at lower H2O2 concentrations. By removing O2 from the sample solution, a more sensitive O2 sensor can be used for measurement. The sensor has been successfully applied in a flow-through cell to measure H2O2 concentration in different flow rates.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Seong Jae Kim, Ji-hun Jeong, Gaabhin Ryu, Yoon Sick Eom, Sanha Kim
Summary: Surface-enhanced Raman spectroscopy (SERS) is a high-sensitivity, label-free detection method with various analytical applications. Researchers have developed a hydrophobic SERS substrate based on engineered carbon nanotube arrays (CNT-SERS) and studied the role of structural design at both micro and nanoscales. The substrate demonstrated controlled self-enrichment capability and enhanced sensitivity, with a significant increase in the SERS signal. The study also proposed a theoretical model and a concentration strategy inspired by plants for analyte deposition on microarrays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Dan Zhao, Renjun Jiang, Xiaoqiang Liu, Subbiah Alwarappan
Summary: In this study, a novel ternary composite material was constructed by assembling cerium vanadate nanorods on reduced graphene oxide-microcrystalline cellulose nanosheets, and it was used for real-time monitoring of the concentration of superoxide anions in vivo. The ternary composite showed excellent conductivity, large surface area, and abundant active sites, leading to a wider linear range, high sensitivity, low detection limit, and fast response time for superoxide anion detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Tengfei Wang, Liwen Wang, Guang Wu, Dating Tian
Summary: In this study, a covalent organic framework material TaTp-COF with porous and uniform spheres was successfully prepared via hydrothermal reaction, and it was found to significantly enhance the aggregation-induced emission (AIE) of berberine. The unique emission properties of berberine on TaTp-COF were studied and utilized for the sensitive detection of berberine.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Lin Li, Yilei Ding, Lei Xu, Shuoran Chen, Guoliang Dai, Pengju Han, Lixin Lu, Changqing Ye, Yanlin Song
Summary: In this study, a novel TTI based on a ratiometric fluorescent nanosensor is designed, which has the advantages of high accuracy and low cost. Experimental and theoretical investigations confirm its pH responsiveness and demonstrate its good sensitivity and reliability. By monitoring the total volatile basic nitrogen, this TTI can accurately predict food spoilage and can be adaptively modified for different types of food. The TTI based on this nanosensor enables visual monitoring of food quality.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Fangju Chen, Xueting Wang, Wei Chen, Chenwen Shao, Yong Qian
Summary: Lung cancer is the second most common malignant tumor worldwide. Drug resistance in lung cancer leads to treatment failure and recurrence in majority of patients. This study developed a fluorescent prodrug that can be activated in cancer cells to release drugs, and its signal can be tracked by imaging. It shows a unique autophagy-driven ferroptosis effect, indicating its potential for targeting drug-resistant cancer cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Weichao Li, Qiming Yuan, Zhangcheng Xia, Xiaoxue Ma, Lifang He, Ling Jin, Xiangfeng Chu, Kui Zhang
Summary: This study developed a high-performance gas sensor for formaldehyde detection by modifying ZnSnO3 with ZnO QDs and SnO2 QDs. The modified sensor showed improved sensing response and lower working temperature. The presence of ZnO QDs formed rich heterojunctions, increased surface area, and provided oxygen deficiency for formaldehyde sensing reaction, thus enhancing the sensor performance. This research provides an alternative method to enhance the sensing properties of MOS by QDs modification.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Joung-Il Moon, Eun Jung Choi, Younju Joung, Jin-Woo Oh, Sang-Woo Joo, Jaebum Choo
Summary: A novel nanoplasmonic substrate was developed for biomedical applications, which showed strong hot spots for detecting biomarkers at low concentrations. The substrate, called AuNPs@M13, was made by immobilizing 60 nm gold nanoparticles onto the surface of an M13 bacteriophage scaffold. It demonstrated higher sensitivity and lower limit of detection compared to commercially available assays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ning Li, Ya Zhang, Ying Xu, Xiaofang Liu, Jian Chen, Mei Yang, Changjun Hou, Danqun Huo
Summary: The molecular subtype of breast cancer guides treatment and drug selection. Invasive tests can promote cancer cell metastasis, so the development of high-performance, low-cost diagnostic tools for cancer prognosis is crucial. Liquid biopsy techniques enable noninvasive, real-time, dynamic, multicomponent, quantitative, and long-term observations at the cellular, genetic, and molecular levels. A Cu-Zr metal-organic framework (MOF) nanoenzyme with monatomic Cu attachment has been synthesized and proven to have high catalytic performance. The sensor constructed using this nanoenzyme shows potential for accurate classification of breast cancer serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Jeongmin Kim, Hyemin Kim, Seunghyun Park, Hyeonaug Hong, Yong Jae Kim, Jiyong Lee, Jaeho Kim, Seung-Woo Cho, Wonhyoung Ryu
Summary: This study presents a method to fabricate independently functioning microneedle (MN) electrodes with narrow intervals for high precision electrochemical sensing. The optimized mixture of photocurable polymer and single-wall carbon nanotubes was used to mold single composite MNs, which were then attached to pre-patterned electrodes. Plasma etching and electropolymerization were performed to enhance the electrochemical activity, and Prussian blue and glucose oxidase were electrodeposited on the MNs for glucose detection. The MN electrodes showed good sensitivity and linearity, and the feasibility of glucose detection was demonstrated in an in vivo mouse study.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
