Article
Chemistry, Analytical
Jungwook Kwon, Ho Young Kang, Haesik Yang
Summary: A new electrochemical method for detecting E. coli was developed in this study, which does not require a permeabilization process. The presence of MPGP during induction of Gal expression led to increased production of MP. The detection limit of this method in both drinking water and tap water was similar to 2 x 10(3) CFU/mL.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Analytical
Stanislav Trashin, Francisco Morales-Yanez, Saranya Thiruvottriyur Shanmugam, Linda Paredis, Erik N. Carrion, Idalia Sariego, Serge Muyldermans, Katja Polman, Sergiu M. Gorun, Karolien De Wael
Summary: A new method for detecting the antigen marker of human toxocariasis is proposed, utilizing a rapid sandwich immunoassay sensor that achieves high sensitivity to pg/mL levels through a redox cycle involving photocatalytic oxidation and electrochemical reduction steps.
ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Jeonghwa Shin, Kiryeon Park, Seonhwa Park, Haesik Yang
Summary: It is more challenging to achieve high signal-to-background ratios in biosensors with electrochemical reduction compared to electrochemical oxidation. This study introduced a method for trypsin detection using electrochemical reduction-based redox cycling, comparing enzymatic and chemical redox cycling. Results showed that using cytochrome c as a redox enzyme in EN redox cycling had lower background levels compared to horseradish peroxidase, leading to more sensitive trypsin detection.
BULLETIN OF THE KOREAN CHEMICAL SOCIETY
(2021)
Review
Chemistry, Analytical
Raina Aman Qazi, Nargis Aman, Nabi Ullah, Nargis Jamila, Naheed Bibi
Summary: The detection of Escherichia coli (E. coli) is crucial for water monitoring, environmental evaluation, and food safety. Current detection methods, although sensitive, are time-consuming and labor-intensive, highlighting the need for a swift, sensitive, simple, and cost-effective alternative. Electrochemical biosensors have emerged as a promising solution due to their sensitivity, fast response, selectivity, low cost, and potential for miniaturization.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Multidisciplinary
Ponnusamy Nandhakumar, Cristina Munoz San Martin, Beatriz Arevalo, Shichao Ding, Mahika Lunker, Eva Vargas, Omeed Djassemi, Susana Campuzano, Joseph Wang
Summary: In order to address the low sensitivity issue of conventional LFA, we report a simple electrochemical LFA with nanocatalytic redox cycling for decentralized insulin detection. This method achieves higher sensitivity than traditional methods by amplifying the signal through nanoparticles and chemical reactions.
Article
Agricultural Engineering
Kevin Munoz, Diego Ahumada, Felipe Arenas, Cecilia Guerrero, Andres Illanes, Carlos Vera
Summary: The study found that butyl-beta-galactoside is significantly more soluble in the organic phase than lactose and monosaccharides. Additionally, higher values of the 1-butanol/aqueous phase ratio were shown to reduce secondary hydrolysis and increase yields. Interfacial properties for butyl-beta-galactoside were also determined at 25 degrees C.
BIORESOURCE TECHNOLOGY
(2021)
Article
Cell Biology
Tom Zimmermann, Michaela Pommer, Viola Kluge, Chafia Chiheb, Susanne Muehlich, Anja-Katrin Bosserhoff
Summary: Detection and quantification of senescent cells is challenging. It is accepted to use a combination of markers and cellular characteristics to define senescent cells in vitro. This study provides a comprehensive comparison of biomarkers and cellular characteristics used to detect senescence in melanocytic systems, aiming to support the development of standardized senescence detection and quantification.
Article
Chemistry, Analytical
Tali Dotan, Aakash Jog, Kian Kadan-Jamal, Adi Avni, Yosi Shacham-Diamand
Summary: This work presents an in vivo stem-mounted sensor for Nicotiana tabacum plants and an in situ cell suspension sensor for Solanum lycopersicum cells. The stem-mounted sensors are stable and less sensitive to plant and air movements compared to leaf-mounted sensors. The sensors utilize interdigitated-electrode-arrays with a dual working electrode configuration and demonstrate signal amplification by redox cycling for enzyme expression detection in plants and cell suspensions, showing potential applications in medical and environmental monitoring systems.
Article
Chemistry, Physical
Mariane Wolf, Elias Basile Tambourgi, Alexandre Tadeu Paulino
Summary: The stability of beta-D-galactosidase immobilized in Arabic gum-based and chitosan-based hydrogels during lactose hydrolysis reactions was investigated. The freeze-dried hydrogel was more suitable for enzyme immobilization, with chitosan-based hydrogel showing higher immobilization capacity. The immobilized enzyme in both hydrogels exhibited better stability in acidic media compared to the free enzyme, an advantage for their application.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2021)
Article
Chemistry, Analytical
Ziheng Hu, Biying Zhao, Ping Miao, Xialing Hou, Feifei Xing, Yingying Chen, Lingyan Feng
Summary: An electrochemical biosensor based on TWJ DNA with LNA as capture probe and enzyme-free signal amplification strategy was developed for sensitive detection of miRNA-21. The sensor showed a linear range from 100 aM to 100 pM and a low detection limit of 77 aM for miRNA-21 detection, demonstrating promising application in direct determination of target miRNA-21 in biological fluids.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Inorganic & Nuclear
Jian Chen, Kouji Taniguchi, Yoshihiro Sekine, Hitoshi Miyasaka
Summary: The iron-based tetraoxolene honeycomb-layered compound was utilized as a cathode material for lithium-ion batteries, showing a charge-cycling performance with specific oxidation-reduction reactions and generation of radicals affecting the magnetic phase transition temperature.
INORGANIC CHEMISTRY
(2021)
Article
Biophysics
Hui Dong, Le Zhao, Xu Zhu, Xiuhua Wei, Menghui Zhu, Qingmin Ji, Xueke Luo, Yintang Zhang, Yanli Zhou, Maotian Xu
Summary: In this study, a turn-on ratiometric electrochemical sensor was fabricated for the detection of beta-Galactosidase. The sensor showed rapid, simple, accurate, and highly sensitive detection with a wide linear range and low detection limit.
BIOSENSORS & BIOELECTRONICS
(2022)
Article
Spectroscopy
Zihong Li, Mingguang Ren, Yuping Zhao, Wenhui Song, Jie Cheng, Weiying Lin
Summary: A novel fluorescent probe ESIPT-GAL based on excited state intramolecular proton transfer mechanism is developed for detecting beta-galactosidase with low background fluorescence and high sensitivity. The probe shows rapid response to beta-galactosidase activity and concentration in living cells and tissues, with good water solubility and the ability to monitor enzyme in deep tissue sections.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Biophysics
Putu Udiyani Prayikaputri, Seonhwa Park, Suhkmann Kim, Young Ho Yoon, Seonghye Kim, Haesik Yang
Summary: Amide hydrolysis is slower than phosphoester and carboxyl ester hydrolysis, but it has lower sensitivity to nonenzymatic spontaneous hydrolysis. This study shows that DT-diaphorase can rapidly catalyze amide hydrolysis and when combined with five redox-cycling reactions, it enables the development of a highly sensitive electrochemical immunosensor.
BIOSENSORS & BIOELECTRONICS
(2023)
Article
Nanoscience & Nanotechnology
Kentaro Ito, Kumi Y. Inoue, Takahiro Ito-Sasaki, Kosuke Ino, Hitoshi Shiku
Summary: A highly sensitive and easy-to-use electrochemical immunoassay using dual-signal amplification strategies of redox cycling within a nanoscale gap and the Limulus amebocyte lysate (LAL) cascade reaction is reported. The method successfully achieved nanomolar sensitivity by utilizing the nanoscale gap for signal amplification.
ACS APPLIED NANO MATERIALS
(2021)
Article
Chemistry, Physical
Vellaiappillai Tamilavan, Yanliang Liu, Insoo Shin, Jihoon Lee, Jung Hyun Jeong, Yun Kyung Jung, Sung Heum Park
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
(2019)
Correction
Chemistry, Analytical
Jungwook Kwon, Eun-Min Cho, Ponnusamy Nandhakumar, Sung Ik Yang, Haesik Yang
ANALYTICAL CHEMISTRY
(2019)
Article
Chemistry, Physical
Vellaiappillai Tamilavan, Insoo Shin, Rajalingam Agneeswari, Yanliang Liu, Yun Kyung Jung, Bo Ram Lee, Youngeup Jin, Jung Hyun Jeong, Myung Ho Hyun, Sung Heum Park
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
(2019)
Article
Chemistry, Analytical
Seonhwa Park, Jihyeon Kim, Seheon Kim, Gyeongho Kim, Nam-Sihk Lee, Young Ho Yoon, Haesik Yang
ANALYTICAL CHEMISTRY
(2019)
Article
Chemistry, Multidisciplinary
Aman Bhatia, Ponnusamy Nandhakumar, Gyeongho Kim, Jihyeon Kim, Nam-Sihk Lee, Young Ho Yoon, Haesik Yang
Article
Energy & Fuels
Rajendra Kumar Gunasekaran, Prem Jyoti Singh Rana, Sung Heum Park, Vellaiappillai Tamilavan, Senthil Karuppanan, Hee-Je Kim, Kandasamy Prabakar
SOLAR ENERGY MATERIALS AND SOLAR CELLS
(2019)
Article
Chemistry, Multidisciplinary
Ponnusamy Nandhakumar, Andi Muhammad Ichzan, Nam-Sihk Lee, Young Ho Yoon, Seohee Ma, Suhkmann Kim, Haesik Yang
Article
Polymer Science
Dal Yong Lee, Vellaiappillai Tamilavan, Insoo Shin, Jihoon Lee, Yun Kyung Jung, Jung Hyun Jeong, Shinuk Cho, Bo Ram Lee, Sung Heum Park
Article
Polymer Science
Vellaiappillai Tamilavan, Soyeong Jang, Jihoon Lee, Rajalingam Agneeswari, Ji Hyeon Kwon, Joo Hyun Kim, Youngeup Jin, Sung Heum Park
Article
Polymer Science
G. Vijayakumar, A. Maruthadurai, R. Paramasivam, V. Tamilavan
INTERNATIONAL JOURNAL OF POLYMER SCIENCE
(2020)
Article
Chemistry, Physical
Vellaiappillai Tamilavan, Insoo Shin, Danbi Kim, Hyun-seock Yang, Pesi Mwitumwa Hangoma, Yun Kyung Jung, Jung Hyun Jeong, Bo Ram Lee, Joo Hyun Kim, Sung Heum Park
JOURNAL OF POWER SOURCES
(2020)
Article
Chemistry, Physical
Vellaiappillai Tamilavan, Yanliang Liu, Insoo Shin, Rajalingam Agneeswari, Hyun-Seock Yang, Danbi Kim, Yong Hyun Kim, Sangwook Wu, Bo Ram Lee, Sung Heum Park
Summary: The study investigates the effect of polymer backbone curvature on the performance of NFA-OSCs, finding that the curvature significantly impacts the nanoscale network formation between the polymer and ITIC, resulting in significant differences in carrier transport and photovoltaic performance.
JOURNAL OF POWER SOURCES
(2021)
Article
Engineering, Electrical & Electronic
G. Vijayakumar, N. Rajiv Chandar, Vellaiappillai Tamilavan, Z. Said, R. Paramasivam
Summary: Synthesized wurtzite ZnO nanostructures incorporated into a PVdF-HFP matrix improve the thermal and porosity properties of the thin film nanocomposite microporous polymer membrane, showing favorable effects on crystallinity and melting temperature to enhance polymer electrolyte conductivity. The resulting polymer membrane demonstrates high porosity and strong film strength, with ionic conductivity suitable for use in lithium ion polymer batteries.
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
(2022)
Article
Polymer Science
Rajalingam Agneeswari, Danbi Kim, Seok Won Park, Soyeong Jang, Hyun Seok Yang, Insoo Shin, Jung Hyun Jeong, Vellaiappillai Tamilavan, Yun Kyung Jung, Sung Heum Park
Summary: The new polymer P(BDT-fPPD) showed distinct properties compared to P(BDT-tPPD), with higher bandgap energy, deeper HOMO level, and higher crystallinity but lower carrier mobility and power conversion efficiency. The differences were attributed to the differences in backbone curvature between the two polymers, impacting their overall performance in organic solar cells.
Article
Chemistry, Physical
Vellaiappillai Tamilavan, Yanliang Liu, Jihoon Lee, Insoo Shin, Yun Kyung Jung, Bo Ram Lee, Jung Hyun Jeong, Sung Heum Park
ACS APPLIED ENERGY MATERIALS
(2019)
Article
Chemistry, Analytical
Mengmeng Guo, Na Luo, Yueling Bai, Zhenggang Xue, Qingmin Hu, Jiaqiang Xu
Summary: A porous heterostructure WO3-C/In2O3 was designed and prepared for a miniature H2 sensor, which showed higher response value, lower operating temperature, fast response-recovery speed, and low limit of detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Feng Hu, Hui Hu, Yuting Li, Xiaohui Wang, Xiaowen Shi
Summary: Arsenic contamination in water bodies is a significant health risk. This study developed a chitosan-catechol modified electrode for rapid and accurate detection of trace amounts of arsenic. The modified electrode demonstrated good detection capability and resistance to ionic interference, making it suitable for in situ detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yantao Zhang, Qian Liu, Tao Tian, Chunhua Xu, Pengli Yang, Lianju Ma, Yi Hou, Hui Zhou, Yongjun Gan
Summary: In this study, a lysosome-targeting buffering fluorogenic probe (Lyso-BFP) was designed and synthesized, demonstrating excellent photostability, pH specificity, and responsiveness to lysosomal acidification in living cells. The performance of Lyso-BFP in pH sensing was attributed to the inhibition of the photo-induced electron transfer process. Lyso-BFP allowed for wash-free imaging and long-term real-time monitoring of lysosome pH changes based on its off-on fluorescence behavior and buffer strategy.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Wei Cai, Wenbo Sun, Jiayue Wang, Xiaokui Huo, Xudong Cao, Xiangge Tian, Xiaochi Ma, Lei Feng
Summary: In this study, a near-infrared fluorescent probe HCBG was developed for imaging of alpha-GLC. HCBG exhibited excellent selectivity and sensitivity towards alpha-GLC in complex bio-samples, and showed good cell permeability for in situ real-time imaging. Through the high-throughput screening system established by HCBG, a natural alpha-GLC inhibitor was successfully isolated and identified. This study provides a novel fluorescence visualization tool for discovering and exploring the biological functions of diabetes-related gut microbiota, and a high-throughput screening approach for alpha-GLC inhibitor.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Trey W. Pittman, Xi Zhang, Chamindie Punyadeera, Charles S. Henry
Summary: Heart failure is a growing epidemic and a significant clinical and public health problem. Researchers have developed a portable and affordable diagnostic device for heart failure that can be used at the point-of-care, providing a valid alternative to current diagnostics approaches.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Anders O. Tjell, Barbara Jud, Roland Schaller-Ammann, Torsten Mayr
Summary: An optical hydrogen peroxide sensor based on catalytic degradation and the detection of produced oxygen is presented. The sensor offers higher resolution and better sensitivity at lower H2O2 concentrations. By removing O2 from the sample solution, a more sensitive O2 sensor can be used for measurement. The sensor has been successfully applied in a flow-through cell to measure H2O2 concentration in different flow rates.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Seong Jae Kim, Ji-hun Jeong, Gaabhin Ryu, Yoon Sick Eom, Sanha Kim
Summary: Surface-enhanced Raman spectroscopy (SERS) is a high-sensitivity, label-free detection method with various analytical applications. Researchers have developed a hydrophobic SERS substrate based on engineered carbon nanotube arrays (CNT-SERS) and studied the role of structural design at both micro and nanoscales. The substrate demonstrated controlled self-enrichment capability and enhanced sensitivity, with a significant increase in the SERS signal. The study also proposed a theoretical model and a concentration strategy inspired by plants for analyte deposition on microarrays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Dan Zhao, Renjun Jiang, Xiaoqiang Liu, Subbiah Alwarappan
Summary: In this study, a novel ternary composite material was constructed by assembling cerium vanadate nanorods on reduced graphene oxide-microcrystalline cellulose nanosheets, and it was used for real-time monitoring of the concentration of superoxide anions in vivo. The ternary composite showed excellent conductivity, large surface area, and abundant active sites, leading to a wider linear range, high sensitivity, low detection limit, and fast response time for superoxide anion detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Tengfei Wang, Liwen Wang, Guang Wu, Dating Tian
Summary: In this study, a covalent organic framework material TaTp-COF with porous and uniform spheres was successfully prepared via hydrothermal reaction, and it was found to significantly enhance the aggregation-induced emission (AIE) of berberine. The unique emission properties of berberine on TaTp-COF were studied and utilized for the sensitive detection of berberine.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Lin Li, Yilei Ding, Lei Xu, Shuoran Chen, Guoliang Dai, Pengju Han, Lixin Lu, Changqing Ye, Yanlin Song
Summary: In this study, a novel TTI based on a ratiometric fluorescent nanosensor is designed, which has the advantages of high accuracy and low cost. Experimental and theoretical investigations confirm its pH responsiveness and demonstrate its good sensitivity and reliability. By monitoring the total volatile basic nitrogen, this TTI can accurately predict food spoilage and can be adaptively modified for different types of food. The TTI based on this nanosensor enables visual monitoring of food quality.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Fangju Chen, Xueting Wang, Wei Chen, Chenwen Shao, Yong Qian
Summary: Lung cancer is the second most common malignant tumor worldwide. Drug resistance in lung cancer leads to treatment failure and recurrence in majority of patients. This study developed a fluorescent prodrug that can be activated in cancer cells to release drugs, and its signal can be tracked by imaging. It shows a unique autophagy-driven ferroptosis effect, indicating its potential for targeting drug-resistant cancer cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Weichao Li, Qiming Yuan, Zhangcheng Xia, Xiaoxue Ma, Lifang He, Ling Jin, Xiangfeng Chu, Kui Zhang
Summary: This study developed a high-performance gas sensor for formaldehyde detection by modifying ZnSnO3 with ZnO QDs and SnO2 QDs. The modified sensor showed improved sensing response and lower working temperature. The presence of ZnO QDs formed rich heterojunctions, increased surface area, and provided oxygen deficiency for formaldehyde sensing reaction, thus enhancing the sensor performance. This research provides an alternative method to enhance the sensing properties of MOS by QDs modification.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Joung-Il Moon, Eun Jung Choi, Younju Joung, Jin-Woo Oh, Sang-Woo Joo, Jaebum Choo
Summary: A novel nanoplasmonic substrate was developed for biomedical applications, which showed strong hot spots for detecting biomarkers at low concentrations. The substrate, called AuNPs@M13, was made by immobilizing 60 nm gold nanoparticles onto the surface of an M13 bacteriophage scaffold. It demonstrated higher sensitivity and lower limit of detection compared to commercially available assays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ning Li, Ya Zhang, Ying Xu, Xiaofang Liu, Jian Chen, Mei Yang, Changjun Hou, Danqun Huo
Summary: The molecular subtype of breast cancer guides treatment and drug selection. Invasive tests can promote cancer cell metastasis, so the development of high-performance, low-cost diagnostic tools for cancer prognosis is crucial. Liquid biopsy techniques enable noninvasive, real-time, dynamic, multicomponent, quantitative, and long-term observations at the cellular, genetic, and molecular levels. A Cu-Zr metal-organic framework (MOF) nanoenzyme with monatomic Cu attachment has been synthesized and proven to have high catalytic performance. The sensor constructed using this nanoenzyme shows potential for accurate classification of breast cancer serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Jeongmin Kim, Hyemin Kim, Seunghyun Park, Hyeonaug Hong, Yong Jae Kim, Jiyong Lee, Jaeho Kim, Seung-Woo Cho, Wonhyoung Ryu
Summary: This study presents a method to fabricate independently functioning microneedle (MN) electrodes with narrow intervals for high precision electrochemical sensing. The optimized mixture of photocurable polymer and single-wall carbon nanotubes was used to mold single composite MNs, which were then attached to pre-patterned electrodes. Plasma etching and electropolymerization were performed to enhance the electrochemical activity, and Prussian blue and glucose oxidase were electrodeposited on the MNs for glucose detection. The MN electrodes showed good sensitivity and linearity, and the feasibility of glucose detection was demonstrated in an in vivo mouse study.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)