Article
Materials Science, Multidisciplinary
Cary A. Kuliasha, Jack W. Judy
Summary: This study presents a rigorous and in-depth analysis on the fabrication and modification of critical materials in thin-film polyimide-metal neuroelectronic interfaces, with a focus on improving the interfacial adhesion between thin films and maximizing device reliability. Methods to enhance metal adherence to polyimide through effective a-SiC:H interfacial layers are identified, along with examples of alloying between adjacent material layers impacting trace resistivity and long-term reliability of the interfaces. The rationale and consequences of key decisions made aim to promote more reproducible science using robust and reliable neuroelectronic technology.
ADVANCED MATERIALS TECHNOLOGIES
(2021)
Article
Engineering, Chemical
Seung Eun Lee, Kyoung-Yong Chun, Jongwoon Kim, Sunghwan Jo, Chang -Soo Han
Summary: The fabrication of advanced membranes with simultaneously high electron and proton conductivities has been achieved through the thermal reduction and vertical confinement of graphene oxide (GO) channels. The improvement in electron conductivity is due to the removal of oxygen functional groups, while the extremely reduced channel size allows for selective proton transport and improved proton selectivity.
JOURNAL OF MEMBRANE SCIENCE
(2022)
Article
Chemistry, Multidisciplinary
Kecheng Guan, Zhaohuan Mai, Siyu Zhou, Shang Fang, Zhan Li, Ping Xu, Yu-Hsuan Chiao, Mengyang Hu, Pengfei Zhang, Guorong Xu, Keizo Nakagawa, Hideto Matsuyama
Summary: Subnanometer interlayer space in graphene oxide (GO) laminates is important for permselective membrane nanochannels. The precise control of nanochannel space and the role of confined nanochannel chemistry in selective water/ion separation are still challenging. This study used macrocyclic molecules with consistent basal plane but varying side groups to modify nanochannels in GO laminates, and demonstrated the side-group dependence of angstrom-precision tunability for channel free space and the energy barrier setting for ion transport. The study provides insights into functional-group-dependent intercalation modifications of GO laminates for structural control and nanochannel design.
Article
Nanoscience & Nanotechnology
Jinlei Yang, Bin Tu, Guangjie Zhang, Pengchao Liu, Kui Hu, Jiarong Wang, Zhuang Yan, Zhiwei Huang, Munan Fang, Junjun Hou, Qiaojun Fang, Xiaohui Qiu, Lianshan Li, Zhiyong Tang
Summary: Osmotic power, or 'blue energy', is a vast and sustainable energy source produced by mixing solutions of different salt concentrations. This study demonstrates the potential application of covalent organic framework monolayer membranes with well-ordered pore arrangement in osmotic power generation, achieving low membrane resistance and high ion conductivity.
NATURE NANOTECHNOLOGY
(2022)
Review
Cell Biology
Bailey Hewlett, Neha Pratap Singh, Christian Vannier, Thierry Galli
Summary: Membrane contact sites play crucial roles in cell differentiation, plasticity and maintenance, and dysfunction can lead to pathological conditions. Each membrane contact site displays a unique molecular signature, adapted to the functions of different organelles.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)
Article
Engineering, Environmental
Bin Wang, Chaoshu Sun, Rongfei Zhou, Weihong Xing
Summary: In this study, tubular and preferentially oriented CHA-type SAPO-34 membranes were prepared by a gel-less method with few liquid wastes. These membranes exhibited good reproducibility and high efficiency. The presence of perpendicular, ordered, and short nanochannels in the SAPO-34 membrane facilitated fast CO2 permeation. The highly-oriented SAPO-34 membrane showed high CO2 permeances and selectivities, making it attractive for highly efficient CO2 capture.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Chemistry, Multidisciplinary
Kecheng Guan, Yuandong Jia, Yuqing Lin, Shengyao Wang, Hideto Matsuyama
Summary: This study developed chemically converted graphene using a one-step method to achieve more stable and functional nanochannels, which can exclude approximately 90% of NaCl solutes from water in a pressure-driven filtration process.
Article
Engineering, Chemical
Zhenzhen Zhang, Md. Mushfequr Rahman, Barbara Bajer, Nico Scharnagl, Volker Abetz
Summary: In this study, a series of porous membranes with different effective pore sizes were successfully prepared using a membrane post-modification technique. The excellent separation performance was demonstrated by separating organic molecules of 1-2 nm in size.
JOURNAL OF MEMBRANE SCIENCE
(2022)
Article
Engineering, Environmental
Surya Padinjarekutt, Huazheng Li, Shoujie Ren, Pranav Ramesh, Fanglei Zhou, Shiguang Li, Georges Belfort, Miao Yu
Summary: Cryogenic condensation is currently used to recover ammonia (NH3) in the energy-intensive Haber-Bosch (HB) process, but there is a need for more energy-efficient technologies for NH3 extraction at elevated temperature and pressure. This study demonstrates that a sodium-gated nanochannel membrane, previously known for its exclusive water conduction abilities, also shows highly selective performance for NH3. Techno-economic analysis shows that using this membrane can lead to more than 80% energy savings and a 20% reduction in net NH3 production cost in the HB process.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Biochemistry & Molecular Biology
Sourayon Chanda, Peichun Amy Tsai
Summary: In this study, diffusionosmotic flow in a charged nanochannel with linearly varying height under an electrolyte concentration gradient is comprehensively investigated through computational fluid dynamics simulations. The effects of cone angle, nanochannel length, tip diameter, concentration difference, and external flow on the diffusioosmotic velocity are analyzed. The results show that the cone angle affects the direction of the diffusionosmotic flow, while the external flow velocity has a negligible influence. Furthermore, the nanochannel length and tip diameter also impact the flow velocity.
Review
Materials Science, Multidisciplinary
Minmin Li, Yuchen Cao, Yuting Xiong, Guangyan Qing
Summary: Biological ion channels have asymmetries in structure and charge distribution, which enable them to perform diverse activities such as signal transduction and cell motility. Inspired by this, researchers have been pursuing artificial ion channels with comparable functions. However, current homogeneous nanochannels have not been able to achieve similar rewards. Hierarchically engineered heterogeneous nanochannels, on the other hand, have shown promising properties such as ion selectivity and permeability, and have found applications in selective ion transport, energy conversion, biomolecular separation, and detection. In this article, recent advances in these hierarchically engineered nanochannel systems are reviewed, with a focus on pore-on-pore and pore-in-pore structures, and their potential applications are discussed.
NPG ASIA MATERIALS
(2023)
Article
Chemistry, Physical
E. J. Smith, A. D. J. Haymet
Summary: The ability of antifreeze proteins and glycoproteins to prevent damage to biological membranes under cold stress is well established, but the exact mechanism of membrane stabilization is still not well understood. In this study, molecular dynamics simulations were conducted to investigate the interaction between a specific antifreeze protein and a lipid bilayer, exploring the location and mode of protein-membrane interaction as well as relevant properties for membrane stabilization.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Engineering, Chemical
Seung-Young Choi, Sungmin Cho, Dongkyu Kim, Jaeyong Kim, Gwangho Song, Rahul Singh, Choongik Kim
Summary: Fine-tuning the nanochannels of ion conducting membrane using heterocyclic imidazole compound as an additive for Nafion effectively enhances membrane performance. The developed membrane with wider and continuous nanochannel configuration, boosted proton conduction through hydrogen bonding interaction, showed improved proton conductivity up to 23% and 50% under high and low humidity condition, respectively. Implemented in fuel cell application, the membrane exhibited enhanced power density without performance degradation.
JOURNAL OF MEMBRANE SCIENCE
(2021)
Article
Chemistry, Multidisciplinary
Jin Wang, Na Jiang, Lele Wang, Di Wang, Xiaoshen Chen, Danxi Huang, Lei Wang
Summary: By incorporating 4-aminobenzo-15-crown-5-ether molecules as specific ion binding sites, we have developed two-dimensional Ti3C2Tx ion nanochannels, which have significant influence on ion transport and improved ion recognition.
Article
Engineering, Chemical
Zhenhua Zhang, Zhihao Liang, Zaichao Guo, Xiaoyu Gui, Muhammad Junaid, Zhuo Zhao, Jingyi Ma, Zhenghui Fang, Dan Mo, Jinglai Duan, Jie Liu, Huijun Yao
Summary: Graphene oxide membrane (GOM) has hydrophilicity and tunable two-dimensional nanochannels, but its instability in solution limits its application in nanofiltration. In this study, we proposed a method to improve the stability and permeability of GOM by constructing vertical channels using swift heavy ion (SHI) irradiation. The results showed that SHI irradiation not only created shortcuts for water permeation but also stabilized the nanochannels by reducing graphene oxide (GO). Furthermore, the rejection of GOM increased due to the reduction of GO layer spacing. Therefore, the bifunctional vertical channels enhanced the stability and nanofiltration performance, providing a new strategy for GOM preparation.
SEPARATION AND PURIFICATION TECHNOLOGY
(2023)
Article
Neurosciences
Argel Aguilar-Valles, Edna Matta-Camacho, Arkady Khoutorsky, Christos Gkogkas, Karim Nader, Jean-Claude Lacaille, Nahum Sonenberg
JOURNAL OF NEUROSCIENCE
(2015)
Article
Oncology
Clara Tenkerian, Jothilatha Krishnamoorthy, Zineb Mounir, Urszula Kazimierczak, Arkady Khoutorsky, Kirk A. Staschke, Arnold S. Kristof, Shuo Wang, Maria Hatzoglou, Antonis E. Koromilas
MOLECULAR CANCER RESEARCH
(2015)
Article
Biology
Arkady Khoutorsky, Robert P. Bonin, Robert E. Sorge, Christos G. Gkogkas, Sophie Anne Pawlowski, Seyed Mehdi Jafarnejad, Mark H. Pitcher, Tommy Alain, Jimena Perez-Sanchez, Eric W. Salter, Loren Martin, Alfredo Ribeiro-de-Silva, Yves De Koninck, Fernando Cervero, Jeffrey S. Mogil, Nahum Sonenberg
Article
Developmental Biology
Agnieszka Skalecka, Ewa Liszewska, Robert Bilinski, Christos Gkogkas, Arkady Khoutorsky, Anna R. Malik, Nahum Sonenberg, Jacek Jaworski
DEVELOPMENTAL NEUROBIOLOGY
(2016)
Article
Multidisciplinary Sciences
Arkady Khoutorsky, Robert E. Sorge, Masha Prager-Khoutorsky, Sophie Anne Pawlowski, Geraldine Longo, Seyed Mehdi Jafarnejad, Soroush Tahmasebi, Loren J. Martin, Mark H. Pitcher, Christos G. Gkogkas, Reza Sharif-Naeini, Alfredo Ribeiro-da-Silva, Charles W. Bourque, Fernando Cervero, Jeffrey S. Mogil, Nahum Sonenberg
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2016)
Article
Multidisciplinary Sciences
Soroush Tahmasebi, Seyed Mehdi Jafarnejad, Ingrid S. Tam, Thomas Gonatopoulos-Pournatzis, Edna Matta-Camacho, Yoshinori Tsukumo, Akiko Yanagiya, Wencheng Li, Yaser Atlasi, Maxime Caron, Ulrich Braunschweig, Dana Pearl, Arkady Khoutorsky, Christos G. Gkogkas, Robert Nadon, Guillaume Bourque, Xiang-Jiao Yang, Bin Tian, Hendrik G. Stunnenberg, Yojiro Yamanaka, Benjamin J. Blencowe, Vincent Giguere, Nahum Sonenberg
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2016)
Article
Biochemistry & Molecular Biology
Ilse Gantois, Arkady Khoutorsky, Jelena Popic, Argel Aguilar-Valles, Erika Freemantle, Ruifeng Cao, Vijendra Sharma, Tine Pooters, Anmol Nagpal, Agnieszka Skalecka, Vinh T. Truong, Shane Wiebe, Isabelle A. Groves, Seyed Mehdi Jafarnejad, Clement Chapat, Elizabeth A. McCullagh, Karine Gamache, Karim Nader, Jean-Claude Lacaille, Christos G. Gkogkas, Nahum Sonenberg
Article
Multidisciplinary Sciences
Alexander H. Tuttle, Shannon Tansley, Kimberly Dossett, Sarasa Tohyama, Arkady Khoutorsky, Sioui Maldonado-Bouchard, Liane Stein, Lindsey Gerstein, Hayley Crawhall-Duk, Rebecca Pearl, Melissa Sukosd, Philip Leger, Oliver M. Hardt, David Yachnin, Jean-Sebastien Austin, Claire M. Chan, Tine Pooters, Isabelle Groves, Loren J. Martin, Nahum Sonenberg, Christos G. Gkogkas, Jeffrey S. Mogil
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2017)
Article
Cell & Tissue Engineering
Soroush Tahmasebi, Tommy Alain, Vinagolu K. Rajasekhar, Jiang-Ping Zhang, Masha Prager-Khoutorsky, Arkady Khoutorsky, Yildirim Dogan, Christos G. Gkogkas, Emmanuel Petroulakis, Annie Sylvestre, Mohammad Ghorbani, Sarah Assadian, Yojiro Yamanaka, Julia R. Vinagolu-Baur, Jose G. Teodoro, Kitai Kim, Xiang-Jiao Yang, Nahum Sonenberg
Article
Neurosciences
Israeli Ran, Christos G. Gkogkas, Cristina Vasuta, Maylis Tartas, Arkady Khoutorsky, Isabel Laplante, Armen Parsyan, Tatiana Nevarko, Nahum Sonenberg, Jean-Claude Lacaille
JOURNAL OF NEUROSCIENCE
(2013)
Article
Multidisciplinary Sciences
Christos G. Gkogkas, Arkady Khoutorsky, Israeli Ran, Emmanouil Rampakakis, Tatiana Nevarko, Daniel B. Weatherill, Cristina Vasuta, Stephanie Yee, Morgan Truitt, Paul Dallaire, Francois Major, Paul Lasko, Davide Ruggero, Karim Nader, Jean-Claude Lacaille, Nahum Sonenberg
Article
Neurosciences
Arkady Khoutorsky, Akiko Yanagiya, Christos G. Gkogkas, Marc R. Fabian, Masha Prager-Khoutorsky, Ruifeng Cao, Karine Gamache, Frederic Bouthiette, Armen Parsyan, Robert E. Sorge, Jeffrey S. Mogil, Karim Nader, Jean-Claude Lacaille, Nahum Sonenberg
Article
Neurosciences
Masha Prager-Khoutorsky, Arkady Khoutorsky, Charles W. Bourque
Article
Cell Biology
Christos G. Gkogkas, Arkady Khoutorsky, Ruifeng Cao, Seyed Mehdi Jafarnejad, Masha Prager-Khoutorsky, Nikolaos Giannakas, Archontia Kaminari, Apostolia Fragkouli, Karim Nader, Theodore J. Price, Bruce W. Konicek, Jeremy R. Graff, Athina K. Tzinia, Jean-Claude Lacaille, Nahum Sonenberg
Article
Biology
Carmela Sidrauski, Diego Acosta-Alvear, Arkady Khoutorsky, Punitha Vedantham, Brain R. Hearn, Han Li, Karine Gamache, Ciara M. Gallagher, Kenny K-H Ang, Chris Wilson, Voytek Okreglak, Avi Ashkenazi, Byron Hann, Karim Nader, Michelle R. Arkin, Adam R. Renslo, Nahum Sonenberg, Peter Walter