期刊
NANO LETTERS
卷 11, 期 7, 页码 2989-2996出版社
AMER CHEMICAL SOC
DOI: 10.1021/nl2015872
关键词
Biomolecular computing; automata; programmable drug; aptamer; disease indicator
类别
资金
- Israel Science Foundation [285/02, 306/05]
- European Union
- Miel de Botton Aynsley and Paul Sparr Foundations
- ISF Converging Technologies [1694/07]
The promise of biomolecular computers is their ability to interact with naturally occurring biomolecules, enabling in the future the development of context-dependent programmable drugs. Here we show a context-sensing mechanism of a biomolecular automaton that can simultaneously sense different types of molecules, allowing future integration of biomedical knowledge on a broad range of molecular disease symptoms in the decision of a biomolecular computer to release a drug molecule.
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