Article
Biochemistry & Molecular Biology
Marta Nowak, Katarzyna Zawadzka, Janusz Szemraj, Aleksandra Goralczyk-Binkowska, Katarzyna Lisowska
Summary: This study investigated the biodegradation mechanism of chloroxylenol by fungal strains and analyzed the ecotoxicity of emerging by-products. The results showed a high elimination rate of PCMX by the tested microorganisms, and the identification of new fungal by-products. Furthermore, the study revealed a detoxifying nature of the biodegradation process of PCMX.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Review
Plant Sciences
Christian Falter, Sigrun Reumann
Summary: This review summarizes recent research results on the novel peroxisomal functions of filamentous fungi and emphasizes the importance of peroxisomes in the infection of host plants. Peroxisomes play a central role in fungal virulence, producing important metabolic products and housing various enzymes.
MOLECULAR PLANT PATHOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Deivid Franca Freitas, Izabelli Martins da Rocha, Olney Vieira-da-Motta, Clovis de Paula Santos
Summary: Melanin is a heteropolymer formed by the polymerization of phenolic and indolic compounds, with various protective advantages such as against ultraviolet radiation, traumatic damage, oxidative stress, extreme temperatures, and pressure. In many fungi, melanin plays a direct role in pathogenicity, with the ability to synthesize it in different ways, either endogenously with 1,8-dihydroxynaphthalene (DHN) or exogenously with L-3, 4-dihydroxyphenylalanine (L-DOPA). The complex and amorphous nature of melanin makes it challenging to study with conventional biochemical techniques, especially in nematophagous fungi which are still poorly understood.
JOURNAL OF CHEMICAL ECOLOGY
(2021)
Article
Polymer Science
Saerom Park, Dahun Jung, Hyejin Do, Jonghyeon Yun, Dongjun Lee, Soeun Hwang, Sang Hyun Lee
Summary: This study developed a laccase-mediator system using natural mediators for melanin decolorization, effectively overcoming issues such as the low redox potential of laccase and limited access of melanin to the active site. Natural mediators with methoxy and ketone groups played a crucial role in melanin decolorization, and using acetosyringone as a mediator significantly enhanced the specificity constants of laccases. The laccase-mediator system could decolorize synthetic eumelanin analogs and natural melanin produced by melanoma cells, showing promising potential for skin whitening applications.
Review
Biochemistry & Molecular Biology
Weronika Slizewska, Katarzyna Struszczyk-Swita, Olga Marchut-Mikolajczyk
Summary: Halophilic filamentous fungi are able to survive in extreme environments and counteract unfavorable conditions by producing multiple secondary metabolites.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Review
Microbiology
Estelle Menu, Quentin Filori, Jean-Charles Dufour, Stephane Ranque, Coralie L'Ollivier
Summary: Humans are frequently exposed to filamentous fungi, which are widespread in the environment. Under certain risk factors, these non-dermatophyte fungi can become opportunistic pathogens and cause various types of infections. The use of molecular tools and taxonomic revisions has led to the identification of an increasing number of fungi in humans. This review aims to inventory these filamentous fungi and provide details on their anatomical locations and the symptoms of infections.
Article
Microbiology
Siriporn Chongkae, Sirida Youngchim, Joshua D. Nosanchuk, Angkana Laliam, Chulaluck Tangmonkongvoragul, Kritsada Pruksaphon
Summary: This study analyzed all FK cases diagnosed in a tertiary care hospital in northern Thailand between August 2012 and December 2020, finding a higher incidence of FK during the rainy season, with males and middle-aged adults being at highest risk. Fusarium spp. and dematiaceous fungi were the main pathogens causing FK, with the hyphal morphogenesis and melanization of molds playing important roles in the disease.
Review
Biotechnology & Applied Microbiology
Audrey Masi, Robert L. Mach, Astrid R. Mach-Aigner
Summary: The pentose phosphate pathway (PPP) is a key pathway in metabolic engineering, providing NADPH and playing a role in the production of various compounds in fungi. Understanding the regulatory mechanisms of PPP can lead to targeted engineering and improved performance in industrial fungal strains.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Mackenzie E. Malo, Zachary Schultzhaus, Connor Frank, Jillian Romsdahl, Zheng Wang, Ekaterina Dadachova
Summary: Melanized fungi isolated from harsh radioactive environments show an adapted strain response to ionizing radiation, with transcriptomic changes and unique gene expression patterns. Exposure to radiation primes the fungus for subsequent exposures in a distinct way, broadening our understanding of how melanized fungi interact with ionizing radiation in their environment.
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL
(2021)
Article
Microbiology
Andrew S. Urquhart, Donald M. Gardiner
Summary: Fungal spore killers are genetic elements that promote their own inheritance by killing non-inheriting gametes. However, little is known about how they kill other spores within the fungal ascus. In this study, we investigate the spore killer protein SPOK1 in Podospora anserina and demonstrate that it kills by targeting DNA. This finding provides insights into the mechanisms of spore killers and their potential applications.
Article
Agronomy
Katariina Manni, Sari Ramo, Marcia Franco, Marketta Rinne, Arto Huuskonen
Summary: The occurrence of mycotoxins in forage, particularly in grass silages, can heavily impact the amount of toxins consumed by cattle. A study conducted in Finland found mycotoxins in 92% of the grass silage and whole-crop cereal silage samples, with beauvericin and roquefortine C being the most common mycotoxins. The survey results suggest that silage-fed ruminants can be exposed to a wide range of mycotoxins, and the presence of visible molds does not guarantee mycotoxin-free feed.
Article
Agriculture, Multidisciplinary
Haiwei Lou, Yang Li, Chuangming Yang, Yonghui Li, Yiyue Gao, Yujin Li, Renyong Zhao
Summary: This study investigated the fermentation conditions for Trametes versicolor to degrade aflatoxin B1 (AFB1) in corn and its effect on the nutritional composition of corn. The optimal conditions for AFB1 degradation were determined, and the fermentation of AFB1-contaminated corn by T. versicolor was found to not only efficiently degrade AFB1 but also improve the nutritional value of corn. These findings suggest that the fermentation of corn by T. versicolor is a promising, environmentally friendly, and efficient approach to degrade AFB1 and improve the nutritional value of corn.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2023)
Article
Environmental Sciences
Lise Alonso, Thomas Pommier, Laurent Simon, Flavien Maucourt, Jeanne Dore, Audrey Dubost, Van Tran Van, Guillaume Minard, Claire Valiente Moro, Christophe J. Douady, Yvan Moenne-Loccoz
Summary: Research suggests that tourism activities in Palaeolithic caves can lead to the formation of black stains, which are caused by pigmented fungi. The study also found that collembola living on these stains can consume and spread the black fungi.
ENVIRONMENTAL MICROBIOLOGY REPORTS
(2023)
Article
Microbiology
Jan Viglas, Petra Olejnikova
Summary: The ABC transporter superfamily plays a crucial role in transporting various molecules across biological membranes, including antifungal compounds in filamentous fungi. Understanding the physiological substrates and roles of individual subfamilies of ABC transporters in fungi is important for clarifying their significance in clinical and agricultural settings.
MICROBIOLOGICAL RESEARCH
(2021)
Article
Medicine, General & Internal
Jeanne Marie Queiroz Borges Bersano, Matheus Gobbo Cordeiro, Fernando Augusto Lima Marson
Summary: This study investigated the incidence and clinical characteristics of onychomycosis in patients on hemodialysis. The results showed that male sex, older age, and the presence of obesity were the main risk factors associated with onychomycosis.
FRONTIERS IN MEDICINE
(2023)
Article
Mycology
Daidi Chen, Hiroshi Masumoto, Yuki Kitade, Kosuke Izumitsu, Chihiro Tanaka
Article
Mycology
Noritaka Nakamura, Tsuyoshi Hosoya, Chihiro Tanaka, Yuko Takeuchi-Kaneko
Article
Mycology
Hiroshi Yoshida, Chihiro Tanaka
Article
Mycology
Noritaka Nakamura, Chihiro Tanaka, Yuko Takeuchi-Kaneko
MYCOLOGICAL PROGRESS
(2019)
Article
Genetics & Heredity
Yuki Kitade, Takuya Sumita, Kosuke Izumitsu, Chihiro Tanaka
Article
Ecology
N. Nakamura, C. Tanaka, Y. Takeuchi-Kaneko
Article
Mycology
Takuya Sumita, Kosuke Izumitsu, Sae Shigeyoshi, Shunsuke Gotoh, Hiroki Yoshida, Kenya Tsuji, Hiroshi Yoshida, Yuki Kitade, Chihiro Tanaka
Article
Mycology
Nitaro Maekawa, Hiroaki Yokoi, Kozue Sotome, Kenji Matsuura, Chihiro Tanaka, Naoki Endo, Akira Nakagiri, Shuji Ushijima
Article
Microbiology
Hiroshi Yoshida, Chihiro Tanaka
Summary: The study demonstrates that l-arabinose enhances resource allocation to asexual reproduction in B. maydis HITO7711 at the cost of vegetative growth, and suggests that this is mediated by the concomitant stimulation of the HMP shunt.
Article
Agronomy
Terufumi Tada, Momo Kato, Chihiro Tanaka, Tatsuhiko Shiraiwa
Summary: The study revealed that soybean seedlings that survived Phytophthora sojae infection had poorer root growth compared to non-inoculated plants, with flooding having limited effects on growth parameters.
PLANT PRODUCTION SCIENCE
(2021)
Article
Mycology
Kenya Tsuji, Yuki Kitade, Takuya Sumita, Chihiro Tanaka
Summary: The study on the function of the Sec5 gene in Bipolaris maydis reveals its impact on hyphal growth and pathogenicity, as well as abnormal development of ascospores in sexual reproduction.
Article
Plant Sciences
Terufumi Tada, Chihiro Tanaka, Tomoyuki Katsube-Tanaka, Tatsuhiko Shiraiwa
Summary: The study found that the development of Phytophthora root and stem rot (PRSR) in soybeans is influenced by the degree of wounding and relative humidity. High humidity stimulates disease incidence. The mortality and infection rates of wounded seedlings vary depending on the depth of the wound and humidity levels.
PHYSIOLOGICAL AND MOLECULAR PLANT PATHOLOGY
(2021)
Article
Biotechnology & Applied Microbiology
Junxian Han, Moriyuki Kawauchi, Yuki Terauchi, Akira Yoshimi, Chihiro Tanaka, Takehito Nakazawa, Yoichi Honda
Summary: Hydrophobins are small-secreted proteins with hydrophobic and hydrophilic parts that can form amphiphilic films at the air-liquid interface. In the white-rot fungus Pleurotus ostreatus, more than 20 hydrophobin genes have been identified. Previous studies have shown that three hydrophobin genes are mainly expressed under ligninolytic conditions, and the vmh3 gene is downregulated in delignification-deficient mutant strains. This study focuses on the function of hydrophobin Vmh3 and demonstrates its role in lignin degradation.
LETTERS IN APPLIED MICROBIOLOGY
(2023)
Article
Mycology
Kenya Tsuji, Yuki Kitade, Akira Yoshimi, Chihiro Tanaka
Summary: This study investigates the functional MSUD system in Bipolaris maydis and suggests that ascus dominance in this fungus is caused by RNA silencing triggered by unpaired DNA, similar to Neurospora crassa. The study also shows the conservation of posttranscriptional regulation in filamentous ascomycetes.
FRONTIERS IN FUNGAL BIOLOGY
(2022)
Article
Mycology
Akira Yoshimi, Daisuke Hagiwara, Miyako Ono, Yasuyuki Fukuma, Yura Midorikawa, Kentaro Furukawa, Tomonori Fujioka, Osamu Mizutani, Natsuko Sato, Ken Miyazawa, Jun-ichi Maruyama, Junichiro Marui, Youhei Yamagata, Tasuku Nakajima, Chihiro Tanaka, Keietsu Abe
Summary: The study found that the HPt protein in the histidine-to-aspartate phosphorelay system plays a crucial role in responding to environmental stresses in the filamentous fungus Aspergillus nidulans. Activation of HPt is associated with cellular responses such as enhanced septation, nuclear fragmentation, and vacuole hypertrophy.
FRONTIERS IN FUNGAL BIOLOGY
(2021)
