Defective expression of SIRT1 contributes to sustain inflammatory pathways in the gut

Identification of a SIRT1 Mutation in a Family with Type 1 Diabetes

(2013) Anna Biason-Lauber et al.   Cell Metabolism

Analysis of the cytokine profile in the duodenal mucosa of refractory coeliac disease patients

(2013) Roberta Caruso et al.   CLINICAL SCIENCE

SIRT1 activation protects against autoimmune T cell-driven retinal disease in mice via inhibition of IL-2/Stat5 signaling

(2013) Peter J. Gardner et al.   JOURNAL OF AUTOIMMUNITY

Musosal tumour necrosis factor α in diverticular disease of the colon is overexpressed with disease severity

(2012) A. Tursi et al.   Colorectal Disease

SIRT1 Activators Suppress Inflammatory Responses through Promotion of p65 Deacetylation and Inhibition of NF-κB Activity

(2012) Hongying Yang et al.   PLoS One

Proinflammatory Cytokines in the Pathogenesis of Inflammatory Bowel Diseases

(2011) Warren Strober et al.   GASTROENTEROLOGY

Sirtuin 1 in immune regulation and autoimmunity

(2011) Sinyi Kong et al.   IMMUNOLOGY AND CELL BIOLOGY

Involvement of interleukin-21 in the regulation of colitis-associated colon cancer

(2011) Carmine Stolfi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Inflammatory Bowel Disease

(2010) Arthur Kaser et al.   Annual Review of Immunology

Myeloid Deletion of SIRT1 Induces Inflammatory Signaling in Response to Environmental Stress

(2010) T. T. Schug et al.   MOLECULAR AND CELLULAR BIOLOGY

Crohn's disease: Th1, Th17 or both? The change of a paradigm: new immunological and genetic insights implicate Th17 cells in the pathogenesis of Crohn's disease

(2009) S. Brand   GUT

The type III histone deacetylase Sirt1 is essential for maintenance of T cell tolerance in mice

(2009) Jinping Zhang et al.   JOURNAL OF CLINICAL INVESTIGATION

Resveratrol (Trans-3,5,4'-trihydroxystilbene) Induces Silent Mating Type Information Regulation-1 and Down-Regulates Nuclear Transcription Factor- B Activation to Abrogate Dextran Sulfate Sodium-Induced Colitis

(2009) U. P. Singh et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

SIRT1, an Antiinflammatory and Antiaging Protein, Is Decreased in Lungs of Patients with Chronic Obstructive Pulmonary Disease

(2008) Saravanan Rajendrasozhan et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Regulation of Gut Inflammation and Th17 Cell Response by Interleukin-21

(2008) Daniele Fina et al.   GASTROENTEROLOGY