Prevention of type 1 diabetes through infection with an intestinal nematode parasite requires IL-10 in the absence of a Th2-type response

An essential role for TH2-type responses in limiting acute tissue damage during experimental helminth infection

(2012) Fei Chen et al.   NATURE MEDICINE

Helminth Protection against Autoimmune Diabetes in Nonobese Diabetic Mice Is Independent of a Type 2 Immune Shift and Requires TGF- 

(2011) M. P. Hubner et al.   JOURNAL OF IMMUNOLOGY

The Th1 life cycle: molecular control of IFN-γ to IL-10 switching

(2011) Andrew Cope et al.   TRENDS IN IMMUNOLOGY

The ‘hygiene hypothesis’ for autoimmune and allergic diseases: an update

(2010) H. Okada et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Naturally Arising Human CD4 T-Cells That Recognize Islet Autoantigens and Secrete Interleukin-10 Regulate Proinflammatory T-Cell Responses via Linked Suppression

(2010) T. I. M. Tree et al.   DIABETES

Subcutaneous insulin B:9-23/IFA immunisation induces Tregs that control late-stage prediabetes in NOD mice through IL-10 and IFNγ

(2010) G. Fousteri et al.   DIABETOLOGIA

Molecular Targeting of Islet Autoantigens

(2010) Brian Stadinski et al.   IMMUNITY

STAT1 Is a Master Regulator of Pancreatic β-Cell Apoptosis and Islet Inflammation

(2010) Fabrice Moore et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IL-2 reverses established type 1 diabetes in NOD mice by a local effect on pancreatic regulatory T cells

(2010) Yenkel Grinberg-Bleyer et al.   JOURNAL OF EXPERIMENTAL MEDICINE

B Cells Have Distinct Roles in Host Protection against Different Nematode Parasites

(2010) Q. Liu et al.   JOURNAL OF IMMUNOLOGY

Sustained signaling by canonical helper T cell cytokines throughout the reactive lymph node

(2010) Georgia Perona-Wright et al.   NATURE IMMUNOLOGY

Unique autoreactive T cells recognize insulin peptides generated within the islets of Langerhans in autoimmune diabetes

(2010) James F Mohan et al.   NATURE IMMUNOLOGY

The geoepidemiology of type 1 diabetes

(2009) Andrea T. Borchers et al.   AUTOIMMUNITY REVIEWS

Helminth Infection Can Reduce Insulitis and Type 1 Diabetes through CD25- and IL-10-Independent Mechanisms

(2009) Q. Liu et al.   INFECTION AND IMMUNITY

Identification and characterization of IL-10/IFN-γ–producing effector-like T cells with regulatory function in human blood

(2009) Barbara Häringer et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Differential Regulation of IL-4R  Expression by Antigen versus Cytokine Stimulation Characterizes Th2 Progression In Vivo

(2009) G. Perona-Wright et al.   JOURNAL OF IMMUNOLOGY

T-bet-Deficient NOD Mice Are Protected from Diabetes Due to Defects in Both T Cell and Innate Immune System Function

(2009) J. H. Esensten et al.   JOURNAL OF IMMUNOLOGY

Autoimmunity: increasing suspects in the CD4+ T cell lineup

(2009) Matthew T Palmer et al.   NATURE IMMUNOLOGY

The "Perfect Storm" for Type 1 Diabetes: The Complex Interplay Between Intestinal Microbiota, Gut Permeability, and Mucosal Immunity

(2008) O. Vaarala et al.   DIABETES

CD40 on NOD CD4 T cells contributes to their activation and pathogenicity

(2008) Rocky L. Baker et al.   JOURNAL OF AUTOIMMUNITY

Innate immunity and intestinal microbiota in the development of Type 1 diabetes

(2008) Li Wen et al.   NATURE

Concordance for Islet Autoimmunity among Monozygotic Twins

(2008) Maria J. Redondo et al.   NEW ENGLAND JOURNAL OF MEDICINE