Article
Obstetrics & Gynecology
Ido Feferkorn, Eva Suarthana, Hormoz Nassiri Kigloo, Ikram Abow-Mohamed, Yasna Golyari, Togas Tulandi
Summary: This study evaluates the combined effects of age and endometriosis on ovarian reserve in women with infertility. The results show that endometriosis is associated with lower anti-Mullerian hormone (AMH) and antral follicular count (AFC), and the impact is more significant in women aged 35 years or older.
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
(2023)
Article
Endocrinology & Metabolism
Qing Wu, Qingmei Yang, Yanling Lin, Lin Wu, Tan Lin
Summary: This study aimed to explore the optimal time for laparoscopic cystectomy in patients with first identified unilateral ovarian endometrioma and evaluate its influence on ovarian reserve. The results showed that the late luteal phase is the optimal time for laparoscopic cystectomy in patients with first identified unilateral ovarian endometrioma, which can effectively protect ovarian tissue and preserve ovarian reserve.
REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Muge Halici, Mustafa Ege Seker, Irem Yagmur Gebedek, Merve Nida Gokbak, Abdurrahman Furkan Cetisli, Ahmet Berkan Ciftci, Emine Konac, Sule Yildirim Kopuk, Bulent Tiras, Yigit Cakiroglu
Summary: This study demonstrates a correlation between TSH and AMH levels in infertile women. A TSH value of 2.88 mIU/L yields the highest AMH result. It was also found that AMH and AFC were positively correlated, while AMH and FSH were negatively correlated.
Article
Genetics & Heredity
Philippe Arvis, Catherine Rongieres, Olivier Pirrello, Philippe Lehert
Summary: By improving the prediction models for ovarian response to stimulation in ART, the reliability of the predictions can be increased. The study found that the previous observed ovarian response is the best predictor, followed by AMH and AFC. The model also showed a significant difference among different reproductive centers.
JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
(2023)
Article
Obstetrics & Gynecology
Shai E. Elizur, Adva Aizer, Michal Yonish, Tal Shavit, Raoul Orvieto, Roy Mashiach, Shlomo B. Cohen, Elad Berkowitz
Summary: This retrospective cohort study aimed to evaluate the outcome of fertility-preservation treatments in women with endometrioma, particularly those with endometrioma larger than 4 cm. The results showed that women who underwent surgery for endometrioma before fertility-preservation treatment had a significant reduction in the number of MII oocytes. However, among those who did not undergo surgery, the size of endometrioma did not affect the outcomes.
REPRODUCTIVE BIOMEDICINE ONLINE
(2023)
Review
Obstetrics & Gynecology
Mio Kobayashi, Yoshikazu Kitahara, Yuko Hasegawa, Yumiko Tsukui, Hikaru Hiraishi, Akira Iwase
Summary: The study suggests that salpingectomy (both unilateral and bilateral) may lead to a decrease in ovarian reserve.
JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Jae Kyung Lee, Kichang Han, Euna Choi, Jinkyung Baek, Hae-Rim Kim, Man-Deuk Kim, Heeyon Kim, Seok Kyo Seo
Summary: This study compares the change in ovarian reserve after catheter-directed ethanol sclerotherapy in patients with recurrent endometrioma and primary endometrioma. The results show that the effect of catheter-directed ethanol sclerotherapy on ovarian reserve is similar in both groups.
EUROPEAN RADIOLOGY
(2023)
Review
Endocrinology & Metabolism
Marcelle Cedars
Summary: This article discusses the integration of anti-Mullerian hormone (AMH) into the diagnosis and treatment of infertility. AMH can be used to estimate ovarian reserve, determine the dosage of ovarian stimulation, and predict stimulation response. However, it does not reflect oocyte health or chances for pregnancy. Low AMH levels may suggest a shortened reproductive window. AMH levels need to be interpreted in the context of the endogenous endocrine environment, and there is an inverse correlation between body mass index and AMH.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Obstetrics & Gynecology
Saeed Alborzi, Tahereh Poordast, Elham Askary, Kefayat Chamanara, Ziba Zahiri Sorouri, Elnaz Hosseini Najar Kellaii, Siavash Pirzadeh Nahooji
Summary: Injecting vasopressin into the mesovarium during endometrioma cystectomy can reduce intraoperative bleeding and electrocoagulation points, but it does not have a significant effect on preserving ovarian reserve.
REPRODUCTIVE BIOMEDICINE ONLINE
(2022)
Article
Medicine, General & Internal
Ozlem Karabay Akgul, Hakan Guraslan, Evrim Ebru Kovalak, Tolga Karacan, Tugba Ozcan Aydin, Tugce Cay
Summary: The size of endometrioma is related to serum Anti-mullerian hormone (AMH), but the size does not affect the AMH values significantly.
JCPSP-JOURNAL OF THE COLLEGE OF PHYSICIANS AND SURGEONS PAKISTAN
(2022)
Article
Obstetrics & Gynecology
Mohammed M. Laqqan, Maged M. Yassin
Summary: This study aims to investigate the best predictor factors for diminished ovarian reserve (DOR) in women under 40 years old. Through a study on 500 women suffering from idiopathic infertility problems, it is found that AMH and AFC levels are the best biomarkers, followed by age.
REPRODUCTIVE SCIENCES
(2023)
Article
Obstetrics & Gynecology
Margaret M. Hopeman, Katherine E. Cameron, Maureen Prewitt, Kurt Barnhart, Jill P. Ginsberg, Mary D. Sammel, Clarisa R. Gracia
Summary: This study developed a clinical predictive tool that accurately predicts the likelihood of diminished ovarian reserve in young cancer patients after chemotherapy using a multivariable logistic regression model. The tool provides useful information based on age, cancer type, exposure to an alkylating agent, and baseline AMH levels.
FERTILITY AND STERILITY
(2021)
Article
Agriculture, Dairy & Animal Science
Rafael H. Alvarez, Keila M. R. Duarte, Joao B. P. Carvalho, Cecilia C. Rocha, A. A. Gilmar Junior, Eduardo Trevisol, Alfredo J. F. Melo, Guilherme Pugliesi
Summary: This study investigates the ovarian volume, antral follicle count (AFC), and ovarian dynamics in cows at different ages. The results show that as cows age, their ovarian volume increases and the number of antral follicles decreases. However, the growth pattern of follicles and the functionality of corpus luteum do not seem to be affected by age.
ANIMAL REPRODUCTION SCIENCE
(2023)
Article
Endocrinology & Metabolism
Kaitlyn E. Collins, Xiyin Wang, Yuliya Klymenko, Noah B. Davis, Maria C. Martinez, Chi Zhang, Kaman So, Aaron Buechlein, Douglas B. Rusch, Chad J. Creighton, Shannon M. Hawkins
Summary: Endometriosis is a risk factor for endometriosis-associated ovarian cancers. Analysis of OCCC samples with concurrent endometriosis revealed upregulation of cell cycle regulation and DNA replication pathways, and downregulation of cytokine receptor signaling and matrisome pathways. MiR-10a-5p was identified as a potentially oncogenic molecule with significant impact.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Obstetrics & Gynecology
Kamila Kolanska, Alice Hours, Laurie Jonquiere, Emmanuelle Mathieu d'Argent, Yohann Dabi, Charlotte Dupont, Cyril Touboul, Jean-Marie Antoine, Nathalie Chabbert-Buffet, Emile Darai
Summary: The study found that a history of mild COVID-19 infection does not appear to affect the ovarian reserve as evaluated by AMH concentrations. While these results are reassuring, further research is needed to assess the actual impact of COVID-19 on pregnancy outcomes in women undergoing ART.
REPRODUCTIVE BIOMEDICINE ONLINE
(2021)
Review
Obstetrics & Gynecology
Savci Bekir Telek, Zeynep Gurbuz, Erkan Kalafat, Baris Ata
Summary: Oral GnRH antagonists appear to be effective in treating bleeding associated with uterine myomas and improving quality of life. Their safety profile is acceptable for short-term use, but lipid metabolism is affected.
JOURNAL OF MINIMALLY INVASIVE GYNECOLOGY
(2022)
Article
Obstetrics & Gynecology
Kiper Aslan, Isil Kasapoglu, Cihan Cakir, Meltem Koc, Murat Deniz Celenk, Baris Ata, Berrin Avci, Gurkan Uncu
Summary: In patients with diminished ovarian reserve (DOR), if there is discordance between antral follicle count (AFC) and anti-Mullerian hormone (AMH), individuals with high AMH and low AFC have a better ovarian response. It is important to assess both AFC and AMH before controlled ovarian hyperstimulation in order to predict ovarian response in DOR patients, rather than assessing AFC or AMH alone.
JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2022)
Article
Obstetrics & Gynecology
Baris Ata, Nathalie Vermeulen, Edgar Mocanu, Luca Gianaroli, Kersti Lundin, Satu Rautakallio-Hokkanen, Juha S. Tapanainen, Anna Veiga
Summary: This article summarizes the impact of SARS-CoV-2 and COVID-19 on human fertility and assisted reproduction, as well as the influence of vaccination. It provides answers to relevant questions for individuals considering pregnancy and healthcare professionals. The findings suggest that SARS-CoV-2 can affect spermatogenesis and menstrual patterns, but has minimal impact on ovarian function and embryo development. COVID-19 infection and vaccination do not negatively affect reproductive outcomes.
HUMAN REPRODUCTION UPDATE
(2023)
Editorial Material
Obstetrics & Gynecology
Baris Ata
Summary: The ultimate measure of success in assisted reproductive technology (ART) is the cumulative live birth rate per ovarian stimulation cycle. Ovarian stimulation has adverse effects on endometrial receptivity and increases the risks of ovarian hyperstimulation syndrome and adverse obstetric and neonatal outcomes. Mild stimulation has been proposed as a safer and cost-effective alternative. However, accumulating data show that ovarian stimulation has no adverse effects and preventive strategies have been introduced. Vitrification allows for cycle segmentation and maximizes the contribution of every oocyte to the cumulative live birth rate.
REPRODUCTIVE BIOMEDICINE ONLINE
(2023)
Editorial Material
Obstetrics & Gynecology
Juan J. Fraire-Zamora, Kashish Sharma, Omar F. Ammar, Claudia Massarotti, Zoya E. Ali, Evelyn E. Telfer, Suzannah Williams, Baris Ata, George Liperis
HUMAN REPRODUCTION
(2023)
Article
Endocrinology & Metabolism
Carol Coughlan, Baris Ata, Raquel Del Gallego, Barbara Lawrenz, Laura Melado, Suzan Samir, Human Fatemi
Summary: This study investigates the temporal relationship between LH and progesterone increase in a natural menstrual cycle. The results suggest that the variation in timing between LH and progesterone rise in ovulatory cycles may have implications for the choice of marker for the start of secretory transformation in frozen embryo transfer cycles. The study provides a representative account of women undergoing frozen embryo transfer in a natural cycle.
REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY
(2023)
Article
Obstetrics & Gynecology
Baris Ata, Alberto Linan, Erkan Kalafat, Francisco Ruiz, Laura Melado, Asina Bayram, Ibrahim Elkhatib, Barbara Lawrenz, Human M. Fatemi
Summary: The endometrial thickness does not independently affect the live birth rate after embryo transfer. Cancelling embryo transfers with an endometrial thickness less than 7 mm may not be justified.
FERTILITY AND STERILITY
(2023)
Article
Obstetrics & Gynecology
D. Romualdi, S. Guideline Grp Unexplained Infertility, B. Ata, S. Bhattacharya, E. Bosch, M. Costello, K. Gersak, R. Homburg, M. Mincheva, R. J. Norman, T. Piltonen, S. Dos Santos-Ribeiro, D. Scicluna, S. Somers, S. K. Sunkara, H. R. Verhoeve, N. Le Clef
Summary: This study aimed to provide recommendations for the management of couples with unexplained infertility (UI) based on the best available evidence. The guideline outlined the definition, diagnosis, and treatment of UI, and formulated 52 recommendations. However, the efficacy, safety, costs, and risks of treatment options for UI have not been thoroughly evaluated.
HUMAN REPRODUCTION
(2023)
Article
Obstetrics & Gynecology
Begum Mathyk, Adina Schwartz, Alan DeCherney, Baris Ata
Summary: A receptive endometrium is crucial for successful embryo implantation, and ultrasonography-measured endometrial thickness is commonly used as an indicator of endometrial receptivity in assisted reproductive technology cycles. Factors like age, oestradiol concentration, and oocyte number affect both endometrial thickness and probability of live birth. Most studies on the relationship between endometrial thickness and embryo transfer outcomes lack proper addressing of confounding factors and have limitations. Despite numerous meta-analyses and large-scale studies, controversy still exists. This article provides a critical review of studies on endometrial thickness and embryo transfer outcomes, highlighting methodological issues and suggesting improvements for future research. Currently available evidence does not support modifying management solely based on arbitrary thresholds of endometrial thickness.
REPRODUCTIVE BIOMEDICINE ONLINE
(2023)
Article
Obstetrics & Gynecology
Baris Ata, Antonio La Marca, Nikolaos Polyzos
Summary: Ovarian stimulation for assisted reproductive technology traditionally starts in the early follicular phase, but recent research suggests that the timing of stimulation does not affect the number or quality of oocytes collected. This provides an opportunity for more flexibility in treatment. Random start cycles, where ovarian stimulation begins at any point in the menstrual cycle, have shown promise in improving individualized care for patients.
REPRODUCTIVE BIOMEDICINE ONLINE
(2023)
Meeting Abstract
Obstetrics & Gynecology
Erkan Kalafat, Batuhan Aslan, Metehan Berkkan, Murat Sonmezer, Cem Somer Atabekoglu, Baris Ata
FERTILITY AND STERILITY
(2022)
Meeting Abstract
Obstetrics & Gynecology
Erkan Kalafat, Savei Bekir Bekir Telek, Zeynep Gurbuz, Baris Ata
FERTILITY AND STERILITY
(2022)
Meeting Abstract
Obstetrics & Gynecology
Erkan Kalafat, Ipek Keles, Engin Turkgeldi, Sule Yildiz, Gurkan Bozdag, Baris Ata
FERTILITY AND STERILITY
(2022)
Article
Medicine, General & Internal
Havva Sezer, Dilek Yazici, Hande Bulut Canbaz, Mehmet Gokhan Gonenli, Aslihan Yerlikaya, Baris Ata, Bahar Bekdemir, Emine Ayca Nalbantoglu
Summary: This study found that a significant proportion of pregnant women refuse to undergo the oral glucose tolerance test (OGTT), making it difficult to accurately determine the frequency of pregnant women with gestational diabetes mellitus (GDM). Neglecting the OGTT may pose risks to the health of both pregnant women and their babies, emphasizing the importance of improving compliance for the prevention and treatment of gestational diabetes.
NORTHERN CLINICS OF ISTANBUL
(2022)
Review
Obstetrics & Gynecology
Pinar Bulutay, Esra Bilir, Sule Yildiz, Baris Ata
Summary: This case report presents a rare case of endometrial metastasis from primary lung cancer. Through clinical examination and histopathology analysis, combined with multiple immunohistochemical panel, the diagnosis of primary lung adenocarcinoma metastasis was confirmed.
TURKISH JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2022)
