Parkinson's syndrome and Parkinson's disease in mitochondrial disorders

Oxidative Stress in Parkinson's Disease

(2010) Chun Zhou et al.   Annals of the New York Academy of Sciences

How could Parkin-mediated ubiquitination of mitofusin promote mitophagy?

(2010) Elena Ziviani et al.   Autophagy

Gender-specific role of mitochondria in the vulnerability of 6-hydroxydopamine-treated mesencephalic neurons

(2010) Magdalena Misiak et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Molecular characterization of dopamine-derived quinones reactivity toward NADH and glutathione: Implications for mitochondrial dysfunction in Parkinson disease

(2010) Marco Bisaglia et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Maternal inheritance and mitochondrial DNA variants in familial Parkinson's disease

(2010) David K Simon et al.   BMC Medical Genetics

Hypokinesia and Rigidity as Clinical Manifestations of Mitochondrial Encephalomyopathy: Report of Three Cases

(2010) P. M. M. Erven et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Mitochondrial proteomics as a selective tool for unraveling Parkinson’s disease pathogenesis

(2010) Ilse Sanet Pienaar et al.   Expert Review of Proteomics

Fibroblast growth factor 9 upregulates heme oxygenase-1 and γ-glutamylcysteine synthetase expression to protect neurons from 1-methyl-4-phenylpyridinium toxicity

(2010) Jui-Yen Huang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Effect of endogenous mutant and wild-type PINK1 on Parkin in fibroblasts from Parkinson disease patients

(2010) A. Rakovic et al.   HUMAN MOLECULAR GENETICS

A pivotal role for PINK1 and autophagy in mitochondrial quality control: implications for Parkinson disease

(2010) C. T. Chu   HUMAN MOLECULAR GENETICS

Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics

(2010) I. Irrcher et al.   HUMAN MOLECULAR GENETICS

Genetic etiology of Parkinson disease associated with mutations in the SNCA, PARK2, PINK1, PARK7, and LRRK2 genes: a mutation update

(2010) Karen Nuytemans et al.   HUMAN MUTATION

Parkinson Disease-associated DJ-1 Is Required for the Expression of the Glial Cell Line-derived Neurotrophic Factor Receptor RET in Human Neuroblastoma Cells

(2010) Rossana Foti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy

(2010) Noriyuki Matsuda et al.   JOURNAL OF CELL BIOLOGY

A neurological perspective on mitochondrial disease

(2010) Robert McFarland et al.   LANCET NEUROLOGY

A double-blind, placebo-controlled study to assess the mitochondria-targeted antioxidant MitoQ as a disease-modifying therapy in Parkinson's disease

(2010) Barry J. Snow et al.   MOVEMENT DISORDERS

POLG1 polyglutamine tract variants associated with Parkinson's disease

(2010) Johanna Eerola et al.   NEUROSCIENCE LETTERS

Parkin overexpression selects against a deleterious mtDNA mutation in heteroplasmic cybrid cells

(2010) D.-F. Suen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin

(2010) Derek P. Narendra et al.   PLOS BIOLOGY

Parkinson's Disease: From Molecular Pathways in Disease to Therapeutic Approaches

(2009) Bobby Thomas   ANTIOXIDANTS & REDOX SIGNALING

Mitochondrial dysfunction in Parkinson's disease

(2009) Konstanze F. Winklhofer et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Cybrid models of Parkinson's disease show variable mitochondrial biogenesis and genotype-respiration relationships

(2009) Paula M. Keeney et al.   EXPERIMENTAL NEUROLOGY

The cybrid model of sporadic Parkinson's disease

(2009) Patricia A. Trimmer et al.   EXPERIMENTAL NEUROLOGY

Differential effects of PINK1 nonsense and missense mutations on mitochondrial function and morphology

(2009) A. Grünewald et al.   EXPERIMENTAL NEUROLOGY

PINK1 mutations and differential effects on mitochondrial function

(2009) EK Tan   EXPERIMENTAL NEUROLOGY

Peroxidase Mechanism of Lipid-dependent Cross-linking of Synuclein with Cytochromec

(2009) Hülya Bayır et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Progressive myoclonic epilepsy as an adult-onset manifestation of Leigh syndrome due to m.14487T>C

(2009) B Dermaut et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Mitochondrial disorders, cognitive impairment and dementia

(2009) Josef Finsterer   JOURNAL OF THE NEUROLOGICAL SCIENCES

Histopathological analysis of skeletal muscle in patients with Parkinson's disease and ‘dropped head’/‘bent spine’ syndrome

(2009) Hans-Jürgen Gdynia et al.   PARKINSONISM & RELATED DISORDERS

PINK1 Defect Causes Mitochondrial Dysfunction, Proteasomal Deficit and α-Synuclein Aggregation in Cell Culture Models of Parkinson's Disease

(2009) Wencheng Liu et al.   PLoS One

Parkinson Phenotype in Aged PINK1-Deficient Mice Is Accompanied by Progressive Mitochondrial Dysfunction in Absence of Neurodegeneration

(2009) Suzana Gispert et al.   PLoS One

PINK1-dependent recruitment of Parkin to mitochondria in mitophagy

(2009) C. Vives-Bauza et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nature of Mitochondrial DNA Deletions in Substantia Nigra Neurons

(2008) Amy K. Reeve et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Relationships among molecular genetic and respiratory properties of Parkinson's disease cybrid cells show similarities to Parkinson's brain tissues

(2008) M. Kathleen Borland et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Mitochondrial diseases mimicking neurotransmitter defects

(2008) Angels Garcia-Cazorla et al.   MITOCHONDRION

Proteomics Analysis Identifies Phosphorylation-dependent α-Synuclein Protein Interactions

(2008) Melinda A. McFarland et al.   MOLECULAR & CELLULAR PROTEOMICS

Neurodegenerative parkinsonism and progressive external ophthalmoplegia with a Twinkle mutation

(2008) Wim Vandenberghe et al.   MOVEMENT DISORDERS

Additive effects of POLG1 and ANT1 mutations in a complex encephalomyopathy

(2008) Giuliana Galassi et al.   NEUROMUSCULAR DISORDERS

Two novel POLG1 mutations in a patient with progressive external ophthalmoplegia, levodopa-responsive pseudo-orthostatic tremor and parkinsonism

(2008) Federica Invernizzi et al.   NEUROMUSCULAR DISORDERS

Alpha-synuclein pathology and Parkinsonism associated withPOLG1mutations and multiple mitochondrial DNA deletions

(2008)   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Parkinsonism associated with the homozygous W748S mutation in the POLG1 gene

(2008) A.M. Remes et al.   PARKINSONISM & RELATED DISORDERS

Noncompaction and endocarditis in suspected mitochondrial disorder

(2007) Josef Finsterer et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

The mtDNA A8344G “MERRF” mutation is not a common cause of sporadic Parkinson disease in Italian population

(2007) Michelangelo Mancuso et al.   PARKINSONISM & RELATED DISORDERS