4.3 Review

MRI evaluation and safety in the developing brain

期刊

SEMINARS IN PERINATOLOGY
卷 39, 期 2, 页码 73-104

出版社

W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1053/j.semperi.2015.01.002

关键词

fetal MR; neonatal MRI; MR spectroscopy; arterial spin label perfusion; MR compatible incubator; NICU magnet

资金

  1. NINDS [K23063371]
  2. Children's Heart Foundation (Chicago)
  3. Ian Harrison Family Neonatal Brain Injury Fund
  4. Twenty Five Club Preterm Brain Injury Fund
  5. Lemieux Foundation
  6. Pittsburgh Children's Hospital Foundation

向作者/读者索取更多资源

Magnetic resonance imaging (MRI) evaluation of the developing brain has dramatically increased over the last decade. Faster acquisitions and the development of advanced MRI sequences, such as magnetic resonance spectroscopy (MRS), diffusion tensor imaging (DTI), perfusion imaging, functional MR imaging (fMRI), and susceptibility-weighted imaging (SWI), as well as the use of higher magnetic field strengths has made MRI an invaluable tool for detailed evaluation of the developing brain. This article will provide an overview of the use and challenges associated with 1.5-T and 3-T static magnetic fields for evaluation of the developing brain. This review will also summarize the advantages, clinical challenges, and safety concerns specifically related to MRI in the fetus and newborn, including the implications of increased magnetic field strength, logistics related to transporting and monitoring of neonates during scanning, and sedation considerations, and a discussion of current technologies such as MRI conditional neonatal incubators and dedicated small-foot print neonatal intensive care unit (NICU) scanners. (C) 2015 Elsevier Inc. All rights reserved.

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