期刊
MOVEMENT DISORDERS
卷 24, 期 14, 页码 S684-S690出版社
WILEY-LISS
DOI: 10.1002/mds.22647
关键词
Parkinson's disease; magnetic resonance imaging; brain iron; cerebral blood flow; brain chemistry
资金
- United States Department of Defense [W81XWH-05-2-0094]
Recent advancements in high field magnetic resonance imaging (MRI) technology (3 T and higher), providing increased signal sensitivity and images with more prominent contrasts intrinsic to the brain, offer new opportunities for assessing brain alterations in Parkinson's disease (PD). In this article, the principle benefits of high field MRI for PD research are described and new findings at high magnetic fields are reviewed. Several high field MRI methodologies, including structural MRI, imaging of brain iron, diffusion tensor imaging, arterial spin labeling perfusion imaging, rotating frame imaging, and magnetic resonance spectroscopy, are critically reviewed for their potential roles in studies of PD. (c) 2009 Movement Disorder Society
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