期刊
MOLECULES
卷 20, 期 1, 页码 1-23出版社
MDPI
DOI: 10.3390/molecules20010001
关键词
biomedical polymers; macromolecular conjugates of drugs; enzymatic ring opening polymerization; ionic liquids; biodegradable polyesters; drug delivery systems
资金
- National Science Centre (Poland) [DEC-2013/11/N/NZ7/02342]
Biodegradable or bioresorbable polymers are commonly used in various pharmaceutical fields (e.g., as drug delivery systems, therapeutic systems or macromolecular drug conjugates). Polyesters are an important class of polymers widely utilized in pharmacy due to their biodegradability and biocompatibility features. In recent years, there has been increased interest in enzyme-catalyzed ring-opening polymerization (e-ROP) of cyclic esters as an alternative method of preparation of biodegradable or bioresorbable polymers. Ionic liquids (ILs) have been presented as green solvents in enzymatic ring-opening polymerization. The activity, stability, selectivity of enzymes in ILs and the ability to catalyze polyester synthesis under these conditions are discussed. Overall, the review demonstrates that e-ROP of lactones or lactides could be an effective method for the synthesis of useful biomedical polymers.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据