Inhibition of Telomerase Activity by Oleanane Triterpenoid CDDO-Me in Pancreatic Cancer Cells is ROS-Dependent
出版年份 2013 全文链接
标题
Inhibition of Telomerase Activity by Oleanane Triterpenoid CDDO-Me in Pancreatic Cancer Cells is ROS-Dependent
作者
关键词
-
出版物
MOLECULES
Volume 18, Issue 3, Pages 3250-3265
出版商
MDPI AG
发表日期
2013-03-14
DOI
10.3390/molecules18033250
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Inhibition of cell proliferation and induction of apoptosis by oleanane triterpenoid (CDDO-Me) in pancreatic cancer cells is associated with the suppression of hTERT gene expression and its telomerase activity
- (2012) Dorrah Deeb et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Nuclear import of hTERT requires a bipartite nuclear localization signal and Akt-mediated phosphorylation
- (2012) J. Chung et al. JOURNAL OF CELL SCIENCE
- Telomerase Reverse Transcriptase (TERT) is a Therapeutic Target of Oleanane Triterpenoid CDDO-Me in Prostate Cancer
- (2012) Yongbo Liu et al. MOLECULES
- Indole-3-carbinol downregulation of telomerase gene expression requires the inhibition of estrogen receptor-alpha and Sp1 transcription factor interactions within the hTERT promoter and mediates the G1 cell cycle arrest of human breast cancer cells
- (2011) C. N. Marconett et al. CARCINOGENESIS
- Sulforaphane decreases viability and telomerase activity in hepatocellular carcinoma Hep3B cells through the reactive oxygen species-dependent pathway
- (2010) Dong-Oh Moon et al. CANCER LETTERS
- Inhibition of NFκB and Pancreatic Cancer Cell and Tumor Growth by Curcumin Is Dependent on Specificity Protein Down-regulation
- (2010) Indira Jutooru et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Methyl 2-Cyano-3,12-dioxooleana-1,9-dien-28-oate Decreases Specificity Protein Transcription Factors and Inhibits Pancreatic Tumor Growth: Role of MicroRNA-27a
- (2010) I. Jutooru et al. MOLECULAR PHARMACOLOGY
- N-acetyl cysteine mitigates curcumin-mediated telomerase inhibition through rescuing of Sp1 reduction in A549 cells
- (2010) I-Lun Hsin et al. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
- Sulforaphane Causes Epigenetic Repression of hTERT Expression in Human Breast Cancer Cell Lines
- (2010) Syed M. Meeran et al. PLoS One
- CDDO-Me: A Novel Synthetic Triterpenoid for the Treatment of Pancreatic Cancer
- (2010) Dorrah Deeb et al. Cancers
- Oleanane triterpenoid CDDO-Me inhibits growth and induces apoptosis in prostate cancer cells through a ROS-dependent mechanism
- (2009) Dorrah Deeb et al. BIOCHEMICAL PHARMACOLOGY
- Tumor cell redox state and mitochondria at the center of the non-canonical activity of telomerase reverse transcriptase
- (2009) Inthrani Raja Indran et al. MOLECULAR ASPECTS OF MEDICINE
- Oleanane Triterpenoid CDDO-Me inhibits growth and induces apoptosis in prostate cancer cells by independently targeting pro-survival Akt and mTOR
- (2009) Dorrah Deeb et al. PROSTATE
- The Thioredoxin System Mediates Redox-Induced Cell Death in Human Colon Cancer Cells: Implications for the Mechanism of Action of Anticancer Agents
- (2008) Y. Sun et al. CANCER RESEARCH
- 4-Hydroxynonenal enhances MMP-2 production in vascular smooth muscle cells via mitochondrial ROS-mediated activation of the Akt/NF-κB signaling pathways
- (2008) Seung J. Lee et al. FREE RADICAL BIOLOGY AND MEDICINE
- Telomere-associated proteins: cross-talk between telomere maintenance and telomere-lengthening mechanisms
- (2008) Gitte De Boeck et al. JOURNAL OF PATHOLOGY
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started