Chemical Methods for Peptide and Protein Production

Azobenzene Photoswitches for Staudinger-Bertozzi Ligation

(2013) Wiktor Szymański et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

2012 FDA drug approvals

(2013) Asher Mullard   NATURE REVIEWS DRUG DISCOVERY

Microwave-assisted synthesis of difficult sequence-containing peptides using the isopeptide method

(2013) Waleed M. Hussein et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Convergent Chemical Synthesis of Proteins by Ligation of Peptide Hydrazides

(2012) Ge-Min Fang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chemical Protein Synthesis by Chemoselective α-Ketoacid-Hydroxylamine (KAHA) Ligations with 5-Oxaproline

(2012) Vijaya R. Pattabiraman et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Sequential α-Ketoacid-Hydroxylamine (KAHA) Ligations: Synthesis of C-Terminal Variants of the Modifier Protein UFM1

(2012) Ayodele O. Ogunkoya et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cyclic analogs of galanin and neuropeptide Y by hydrocarbon stapling

(2012) Brad R. Green et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Peptides As Therapeutics with Enhanced Bioactivity

(2012) D. Goodwin et al.   CURRENT MEDICINAL CHEMISTRY

Impact of dendritic cell vaccines pulsed with Wilms’ tumour-1 peptide antigen on the survival of patients with advanced non-small cell lung cancers

(2012) Hidenori Takahashi et al.   EUROPEAN JOURNAL OF CANCER

Type 1 diabetes: primary antigen/peptide/register/trimolecular complex

(2012) Tomasz Sosinowski et al.   IMMUNOLOGIC RESEARCH

Staple Motifs, Initial Steps in the Formation of Thiolate-Protected Gold Nanoparticles: How Do They Form?

(2012) Víctor Rojas-Cervellera et al.   INORGANIC CHEMISTRY

Structure–Activity Relationship for the Development of a Self-Adjuvanting Mucosally Active Lipopeptide Vaccine against Streptococcus pyogenes

(2012) Mehfuz Zaman et al.   JOURNAL OF MEDICINAL CHEMISTRY

Novel Protein Therapeutics for Systolic Heart Failure

(2012) Horng H. Chen et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

2011 FDA drug approvals

(2012) Asher Mullard   NATURE REVIEWS DRUG DISCOVERY

Lipo-Endomorphin-1 Derivatives with Systemic Activity against Neuropathic Pain without Producing Constipation

(2012) Pegah Varamini et al.   PLoS One

Peptide-Based Subunit Vaccine against Hookworm Infection

(2012) Mariusz Skwarczynski et al.   PLoS One

Protein Chemical Synthesis by Ligation of Peptide Hydrazides

(2011) Ge-Min Fang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Microwave heating in solid-phase peptide synthesis

(2011) Søren L. Pedersen et al.   CHEMICAL SOCIETY REVIEWS

2010 FDA drug approvals

(2011) Asher Mullard   NATURE REVIEWS DRUG DISCOVERY

Site-specific protein double labeling by expressed protein ligation: applications to repeat proteins

(2011) Lucia De Rosa et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

The influence of incorporating lipids or liposaccharides on the particle size of peptide therapeutics

(2010) Daniel J. Coles et al.   BIOPOLYMERS

2009 FDA drug approvals

(2010) Bethan Hughes   NATURE REVIEWS DRUG DISCOVERY

Design and Synthesis of Lipopeptide–Carbohydrate Assembled Multivalent Vaccine Candidates Using Native Chemical Ligation

(2009) Wei Zhong et al.   AUSTRALIAN JOURNAL OF CHEMISTRY

Synthetic therapeutic peptides: science and market

(2009) Patrick Vlieghe et al.   DRUG DISCOVERY TODAY

Modern lipid-, carbohydrate-, and peptide-based delivery systems for peptide, vaccine, and gene products

(2009) Pavla Simerska et al.   MEDICINAL RESEARCH REVIEWS

Development of highly pure α-helical lipoglycopeptides as self-adjuvanting vaccines

(2009) Wei Zhong et al.   TETRAHEDRON

An Efficient Fmoc-SPPS Approach for the Generation of Thioester Peptide Precursors for Use in Native Chemical Ligation

(2008) Juan B. Blanco-Canosa et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis and in vivo studies of carbohydrate-based vaccines against group A Streptococcus

(2008) Pavla Simerska et al.   BIOPOLYMERS

Development of a Liposaccharide-Based Delivery System and Its Application to the Design of Group A Streptococcal Vaccines

(2008) Pavla Simerska et al.   JOURNAL OF MEDICINAL CHEMISTRY

Mirror Image Forms of Snow Flea Antifreeze Protein Prepared by Total Chemical Synthesis Have Identical Antifreeze Activities

(2008) Brad L. Pentelute et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

X-ray Structure of Snow Flea Antifreeze Protein Determined by Racemic Crystallization of Synthetic Protein Enantiomers

(2008) Brad L. Pentelute et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structure–Activity Relationship of a Series of Synthetic Lipopeptide Self-Adjuvanting Group A Streptococcal Vaccine Candidates

(2007) Abu-Baker M. Abdel-Aal et al.   JOURNAL OF MEDICINAL CHEMISTRY