Design, Synthesis and Evaluation of N13-Substituted Evodiamine Derivatives against Human Cancer Cell Lines

Synthesis and Evaluation of Some 17-Acetamidoandrostane and N,N-Dimethyl-7-deoxycholic Amide Derivatives as Cytotoxic Agents: Structure/Activity Studies

(2013) Yanmin Huang et al.   MOLECULES

Pharmacological Actions of Multi-Target-Directed Evodiamine

(2013) Hui Yu et al.   MOLECULES

Anti-Proliferative Effects of Evodiamine on Human Breast Cancer Cells

(2013) Kai-Lee Wang et al.   PLoS One

Evodiamine inhibits STAT3 signaling by inducing phosphatase shatterproof 1 in hepatocellular carcinoma cells

(2012) Jie Yang et al.   CANCER LETTERS

Design, synthesis and in vitro and in vivo antitumor activities of novel bivalent β-carbolines

(2012) Buxi Shi et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Enhanced Antitumor Efficacy of Gemcitabine by Evodiamine on Pancreatic Cancer via Regulating PI3K/Akt Pathway

(2012) Wei-Tian Wei et al.   International Journal of Biological Sciences

New Tricks for an Old Natural Product: Discovery of Highly Potent Evodiamine Derivatives as Novel Antitumor Agents by Systemic Structure–Activity Relationship Analysis and Biological Evaluations

(2012) Guoqiang Dong et al.   JOURNAL OF MEDICINAL CHEMISTRY

Evodiamine, a dual catalytic inhibitor of type I and II topoisomerases, exhibits enhanced inhibition against camptothecin resistant cells

(2012) Xiaobei Pan et al.   PHYTOMEDICINE

Synthesis and cytotoxicity of 17a-aza-d-homo-androster-17-one derivatives

(2011) Yanmin Huang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and biological evaluation of 1,9-disubstituted β-carbolines as potent DNA intercalating and cytotoxic agents

(2011) Zhiyong Chen et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Evodiamine induces caspase-dependent apoptosis and S phase arrest in human colon lovo cells

(2010) Chun Zhang et al.   ANTI-CANCER DRUGS

Synthesis of novel β-carbolines with efficient DNA-binding capacity and potent cytotoxicity

(2010) Zhiyong Chen et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Targeting apoptosis pathways in cancer by Chinese medicine

(2010) Min Li-Weber   CANCER LETTERS

Synthesis and cytotoxic evaluation of 1-carboxamide and 1-amino side chain substituted β-carbolines

(2010) Chunming Ma et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Anti-Proliferative Effects of Evodiamine on Human Thyroid Cancer Cell Line ARO

(2010) Meng-Ching Chen et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Selection of Evodiamine as a Novel Topoisomerase I Inhibitor by Structure-Based Virtual Screening and Hit Optimization of Evodiamine Derivatives as Antitumor Agents

(2010) Guoqiang Dong et al.   JOURNAL OF MEDICINAL CHEMISTRY

Antiproliferation and Apoptosis Induced by Evodiamine in Human Colorectal Carcinoma Cells (COLO-205)

(2009) Zhi-Gang Yang et al.   CHEMISTRY & BIODIVERSITY

Evodiamine inhibits adipogenesis via the EGFR-PKCα-ERK signaling pathway

(2009) Ting Wang et al.   FEBS LETTERS

Determination of drug-like properties of a novel antileishmanial compound: In vitro absorption, distribution, metabolism, and excretion studies

(2009) NirupB Mondal et al.   INDIAN JOURNAL OF PHARMACOLOGY

Evodiamine: A Novel Anti-Cancer Alkaloid from Evodia rutaecarpa

(2009) Junlin Jiang et al.   MOLECULES

Evodiamine Stabilizes Topoisomerase I-DNA Cleavable Complex to Inhibit Topoisomerase I Activity

(2009) Agnes Chan et al.   MOLECULES

Evodiamine-induced human melanoma A375-S2 cell death was mediated by PI3K/Akt/caspase and Fas-L/NF-κB signaling pathways and augmented by ubiquitin–proteasome inhibition

(2009) Che Wang et al.   TOXICOLOGY IN VITRO