期刊
MOLECULES
卷 17, 期 9, 页码 11046-11055出版社
MDPI AG
DOI: 10.3390/molecules170911046
关键词
single-step synthesis; iodine(III); oxazole; ketone; nitrile
资金
- MEXT Japan [24790024]
- Grants-in-Aid for Scientific Research [24790024, 22590016] Funding Source: KAKEN
In the presence of trifluoromethanesulfonic acid (TfOH) or bis(trifluoromethanesulfonyl) imide (Tf2NH), iodosobenzene (Phl=O) efficiently promoted the reactions of dicarbonyl compounds as well as monocarbonyl compounds with nitriles to give 2,4-disubstituted and 2,4,5-trisubstituted oxazole in a single step under the mild conditions.
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