期刊
MOLECULES
卷 17, 期 12, 页码 14409-14417出版社
MDPI AG
DOI: 10.3390/molecules171214409
关键词
unnatural nucleosides; Suzuki-Miyaura coupling; aqueous conditions
Following our previous results on an environmentally benign one-pot Sonogashira-cyclization protocol to obtain substituted furopyrimidine nucleosides under aqueous conditions, we investigate herein the Suzuki-Miyaura cross-coupling reactions of aryl and heteroaryl derivatives at the C5 position of unprotected 2'-deoxyuridine in the same media with a common catalyst system avoiding exotic ligands, since palladium acetate and triphenylphosphine afforded the expected products in moderate to good yields.
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