期刊
MOLECULES
卷 17, 期 11, 页码 13175-13182出版社
MDPI AG
DOI: 10.3390/molecules171113175
关键词
gamma-butenolide derivatives; spiculisporic acids B-D; Aspergillus sp.; marine fungus
资金
- Science and Technology Program of Hainan Province
- Fundamental Research Foundation for Youth, Hainan Provincial Fisheries Research Institute [20091006]
Three new gamma-butenolide derivatives 1-3, named spiculisporic acids B-D, were isolated from the culture of Aspergillus sp. HDf2, a marine-derived fungus that resides in the sea urchin, Anthocidaris crassispina. The structures of 1-3 were elucidated on the basis of spectroscopic methods, including MS and 2D NMR techniques. Their in vitro cytotoxic activities against two cell lines (SGC-7901, human gastric adenocarcinoma and SPC-A-1, human lung adenocarcinoma) and inhibitory activities against Staphylococcus aureus ATCC 51650 were investigated.
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