Article
Medicine, Research & Experimental
Roland Bottger, Po-Han Chao, Nojoud AL Fayez, Griffin Pauli, Anne Nguyen, Lukas Hohenwarter, Nida Bilal, Gubran Khalil Mohammed, Daniel Knappe, Ralf Hoffmann, Shyh-Dar Li
Summary: Excipients in nanomedicines play a critical role in determining product quality, stability, consistency, and safety. This study developed a HPLC method combined with an ELS detector and a UV-vis detector to simultaneously analyze drugs and excipients in nanomedicines. This method can be applied to various nanodrug delivery systems and provides important information for nanomedicine formulation development.
MOLECULAR PHARMACEUTICS
(2022)
Article
Chemistry, Physical
Wenchang Wu, Junwei Cui, Umair Sultan, Lukas Gromotka, Paolo Malgaretti, Cornelia Damm, Jens Harting, Nicolas Vogel, Wolfgang Peukert, Alexandra Inayat, Andreas P. Froeba
Summary: The applicability of dynamic light scattering for determining particle diffusivity under confinement without refractive index matching has not been fully explored. Furthermore, the effect of confinement on particle diffusion in porous materials relevant to particle chromatography has not been fully characterized.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2023)
Article
Engineering, Chemical
Thossaporn Wijakmatee, Yusuke Shimoyama, Yasuhiko Orita
Summary: Combination of micro-flow processes between emulsification and supercritical fluid emulsion extraction was used to fabricate stable and uniform stearic acid lipid nanoparticles dispersed in aqueous solution.
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
(2022)
Review
Chemistry, Multidisciplinary
Thiruchelvi Pulingam, Parisa Foroozandeh, Jo-Ann Chuah, Kumar Sudesh
Summary: This review article discusses the different methods employed for the production of polymeric nanoparticles (PNPs) and their physicochemical properties influenced by experimental parameters. The tailored characteristics of PNPs can be utilized as drug carriers for targeted therapies in hospitals for point-of-care diagnostics.
Article
Chemistry, Analytical
Maria Antonio, Tania Lima, Rui Vitorino, Ana L. Daniel-da-Silva
Summary: A simple method for label-free detection of CRP in saliva samples was developed using silica-coated Fe3O4 nanoparticles functionalized with amino carboxylate moieties. The nanoparticles showed higher selectivity towards CRP compared to nonfunctionalized nanoparticles, providing more accurate detection of CRP concentration.
ANALYTICA CHIMICA ACTA
(2022)
Article
Optics
Q. Zhang, D. L. Gao, L. Gao
Summary: This paper demonstrates the dynamic tunability of spin Hall shift of light by changing the Fermi level of graphene-wrapped spheres, especially prominent when different modes interfere with each other. The circular polarization degree in the near field shows the strength of spin-orbit interaction, and the spin Hall effect should be observable in far-field detection in experiments.
Article
Chemistry, Analytical
Thanisorn Mahatnirunkul, Darren C. Tomlinson, Michael J. McPherson, Paul A. Millner
Summary: Gold nanoparticle (AuNPs) coupled dynamic light scattering (DLS) is a biosensing technique that combines the light scattering properties of AuNPs with analyte recognition to create a user-friendly analytical tool. By immobilizing bioreceptors onto AuNPs, the binding of target protein to the bioreceptors leads to a size shift in the functionalized AuNPs, which can be quantified using DLS. This technique has been proven effective in detecting various analytes.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Biotechnology & Applied Microbiology
Ankur Sharma, Susan Hawthorne, Saurabh Kumar Jha, Niraj Kumar Jha, Dhruv Kumar, Samuel Girgis, Vineet Kumar Goswami, Gaurav Gupta, Sachin Singh, Harish Dureja, Dinesh Kumar Chellappan, Kamal Dua
Summary: The study demonstrated the significant antitumor effect of curcumin-loaded PLGA nanoparticles on MDA-MB231 human breast cancer cells, showing high encapsulation efficiency and sustained payload release.
Article
Engineering, Chemical
Bingyao Wang, Tianyi Cai, Xiaoshu Cai, Wu Zhou, Zeqi Liu
Summary: The size and morphology of nanoparticles significantly impact their performance. Current methods, such as electron microscopy or atomic force microscopy, have limitations in sample preparation, processing time, and quantitative characterization. Therefore, it is crucial to develop a fast, accurate, and statistical method for measuring nanoparticle size and morphology. In this study, a new method called polarized imaging dynamic light scattering (PIDLS) is proposed, which irradiates nanoparticles with a vertical linearly polarized laser beam and utilizes a polarization camera to collect dynamic light scattering images at different polarization directions. The method effectively determines particle size, morphology, and sphericity based on depolarization patterns and degree of linear polarization. PIDLS also enables simultaneous measurement of particle size and morphology distributions, allowing for the evaluation of particle uniformity. The effectiveness of PIDLS is validated with the measurement of five types of industrial titanium dioxide.
Article
Chemistry, Physical
Joe J. Bradley, Vincent A. Martinez, Jochen Arlt, John R. Royer, Wilson C. K. Poon
Summary: Differential dynamic microscopy (DDM) can be used to measure the particle size distribution of multimodal suspensions without prior knowledge. By selectively analyzing different regions of DDM images, it is possible to separate and measure particles of different sizes.
Article
Chemistry, Multidisciplinary
Jennyfer Zapata-Farfan, Morteza Hasanzadeh Kafshgari, Sergiy Patskovsky, Michel Meunier
Summary: Culture-based diagnosis of bacterial diseases is time-consuming and can lead to antibiotic resistance or bacterial mutation. A molecular-level diagnostic technique that is widely available and requires no complex analysis or expensive equipment is of great interest. In this study, a promising analytical approach using nanoplasmonic biomarkers is presented, which can accurately detect pathogenic bacteria. These biomarkers, possessing greater photostability and biocompatibility, serve as selective markers and amplifying agents in optical biomedical detection. The proposed system shows potential for rapid diagnostic tests as point-of-care devices in emergency departments, clinics, and public hospitals.
Article
Materials Science, Multidisciplinary
Gianni Jacucci, Brooke W. Longbottom, Christopher C. Parkins, Stefan A. F. Bon, Silvia Vignolini
Summary: Scattering enhancers are nanomaterials used in various materials, modifying the morphology of scattering elements to optimize scattering efficiency. Anisotropic sphero-cylindrical particles have been shown to outperform their isotropic counterparts, achieving excellent scattering performance across the visible electromagnetic spectrum.
JOURNAL OF MATERIALS CHEMISTRY C
(2021)
Article
Nanoscience & Nanotechnology
Young Joon Han, Kyung-Tae Kang, Kwan Hyun Cho
Summary: The study found that different film-formation methods can affect the optimal annealing temperature for zinc oxide nanoparticle electron transport layer under intense pulsed light conditions. Spin-coated and inkjet-printed ZnO NP ETLs exhibit different surface morphologies after IPL post-treatment.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Thermodynamics
Vahid Ahmadi, Aria H. Fahim, Sajad Jabari Neek, Hojat Ghassemi
Summary: This study uses molecular dynamic simulation to investigate the flash evaporation process of light alkanes at different temperatures. The results show that the heavier the alkane, the later the saturation condition is obtained. The final equilibrium temperature of the flash evaporation is considerably lower than the initial temperature of the liquid. Furthermore, the flash evaporation rate is found to be independent of the volume of the environment, indicating the scalability of the flash evaporation process based on the liquid surface area.
THERMAL SCIENCE AND ENGINEERING PROGRESS
(2023)
Article
Chemistry, Physical
Reece Nixon-Luke, Jochen Arlt, Wilson C. K. Poon, Gary Bryant, Vincent A. Martinez
Summary: This study systematically investigates the capability of Differential Dynamic Microscopy (DDM) to characterize particle dynamics in turbid colloidal suspensions, finding that DDM can obtain reliable diffusion coefficients at higher particle concentrations compared to other techniques. The research also reveals the appearance of short-time and long-time processes as turbidity increases, which can be used to estimate the particle size of non-interacting particles. Additionally, a simple theoretical framework, ms-DDM, is provided for turbid samples, taking into account multiple scattering.
Article
Chemistry, Multidisciplinary
Lorenzo Mosca, Jan Cejka, Bohumil Dolensky, Martin Havlik, Milan Jakubek, Robert Kaplanek, Vladimir Kral, Pavel Anzenbacher
CHEMICAL COMMUNICATIONS
(2016)
Article
Chemistry, Multidisciplinary
T. V. Shishkanova, M. Havlik, M. Dendisova, P. Matejka, V. Kral
CHEMICAL COMMUNICATIONS
(2016)
Article
Chemistry, Applied
Zdenek Kejik, Tomas Briza, Martin Havlik, Bohumil Dolensky, Robert Kaplanek, Jarmila Kralova, Ivan Mikula, Pavel Martasek, Vladimir Kral
Article
Polymer Science
A. Bogomolova, L. Kaberov, O. Sedlacek, S. K. Filippov, P. Stepanek, V. Kral, X. Y. Wang, S. L. Liu, X. D. Ye, M. Hruby
EUROPEAN POLYMER JOURNAL
(2016)
Article
Chemistry, Multidisciplinary
Milan Jakubek, Zdenek Kejik, Vaclav Parchansky, Robert Kaplanek, Liudmila Vasina, Pavel Martasek, Vladimir Kral
SUPRAMOLECULAR CHEMISTRY
(2017)
Article
Biochemistry & Molecular Biology
Ivan Stupak, Sylvie Pavlokova, Jakub Vyslouzil, Jiri Dohnal, Martin Culen
Article
Chemistry, Analytical
Zdenek Kejik, Martin Havlik, Tomas Briza, Robert Kaplanek, Bohumil Dolensky, Jarmila Kralova, Pavel Martasek, Vladimir Kral
SENSORS AND ACTUATORS B-CHEMICAL
(2017)
Review
Pharmacology & Pharmacy
Z. Cernickova, J. Dohnal, J. Saloun
INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES
(2018)
Review
Veterinary Sciences
H. Potockova, P. Kusnierik, J. Dohnal
Article
Chemistry, Physical
Ingrid Brezaniova, Jiri Trousil, Zulfiya Cernochova, Vladimir Kral, Martin Hruby, Petr Stepanek, Miroslav Slouf
COLLOID AND POLYMER SCIENCE
(2017)
Article
Biochemical Research Methods
David Sykora, Jiri Vozka, Eva Tesarova, Kveta Kalikova, Martin Havlik, Pavel Matejka, Vladimir Kral
Review
Biochemistry & Molecular Biology
Zdenek Kejik, Robert Kaplanek, Martin Havlik, Tomas Briza, Milan Jakubek, Jarmila Kralova, Ivan Mikula, Pavel Martasek, Vladimir Kral
BIOORGANIC & MEDICINAL CHEMISTRY
(2017)
Article
Electrochemistry
Tatiana V. Shishkanova, Martin Havlik, Vladimir Kral, Dusan Kopecky, Pavel Matejka, Marcela Dendisova, Vladimir M. Mirsky
ELECTROCHIMICA ACTA
(2017)
Article
Pharmacology & Pharmacy
Valeryia Stukina, Jiri Dohnal, Jan Saloun
ACTA POLONIAE PHARMACEUTICA
(2016)
Article
Chemistry, Analytical
Aneta Cernikova, Pavel Bobal, Janette Bobalova, Jiri Dohnal, Josef Jampilek
ACTA CHROMATOGRAPHICA
(2018)