Functional genetic variants that increase synaptic serotonin and 5-HT3 receptor sensitivity predict alcohol and drug dependence

HTR3B is associated with alcoholism with antisocial behavior and alpha EEG power—an intermediate phenotype for alcoholism and co-morbid behaviors

(2009) Francesca Ducci et al.   ALCOHOL

Differential role of serotonergic polymorphisms in alcohol and heroin dependence

(2009) Pilar A. Saiz et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Addictions Biology: Haplotype-Based Analysis for 130 Candidate Genes on a Single Array

(2008) C. A. Hodgkinson et al.   ALCOHOL AND ALCOHOLISM

Effect of Naltrexone and Ondansetron on Alcohol Cue–Induced Activation of the Ventral Striatum in Alcohol-Dependent People

(2008) Hugh Myrick et al.   ARCHIVES OF GENERAL PSYCHIATRY

Naturally occurring variants in the HTR3B gene significantly alter properties of human heteromeric 5-hydroxytryptamine-3A/B receptors

(2008) Jutta Walstab et al.   Pharmacogenetics and Genomics

High-frequency HTR3B variant associated with major depression dramatically augments the signaling of the human 5-HT3AB receptor

(2008) K. Krzywkowski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

3B but which 3B? And that's just one of the questions: the heterogeneity of human 5-HT3 receptors

(2008) A JENSEN et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Update on neuropharmacological treatments for alcoholism: Scientific basis and clinical findings

(2007) Bankole A. Johnson   BIOCHEMICAL PHARMACOLOGY