Spinal 5-HT3 Receptors Mediate Descending Facilitation and Contribute to Behavioral Hypersensitivity via a Reciprocal Neuron-Glial Signaling Cascade

Central Terminal Sensitization of TRPV1 by Descending Serotonergic Facilitation Modulates Chronic Pain

(2014) Yu Shin Kim et al.   NEURON

Transition to Persistent Orofacial Pain after Nerve Injury Involves Supraspinal Serotonin Mechanisms

(2013) M. Okubo et al.   JOURNAL OF NEUROSCIENCE

Lack of analgesic efficacy of spinal ondansetron on thermal and mechanical hypersensitivity following spinal nerve ligation in the rat

(2010) Christopher M. Peters et al.   BRAIN RESEARCH

Molecular Depletion of Descending Serotonin Unmasks Its Novel Facilitatory Role in the Development of Persistent Pain

(2010) F. Wei et al.   JOURNAL OF NEUROSCIENCE

Interactions between the immune and nervous systems in pain

(2010) Ke Ren et al.   NATURE MEDICINE

Spinal cord mechanisms mediating behavioral hyperalgesia induced by neurokinin-1 tachykinin receptor activation in the rostral ventromedial medulla

(2010) S.C. LaGraize et al.   NEUROSCIENCE

Subtype-specific changes in 5-HT receptor-mediated modulation of C fibre-evoked spinal field potentials are triggered by peripheral nerve injury

(2010) Z. Aira et al.   NEUROSCIENCE

Targeting astrocyte signaling for chronic pain

(2010) Yong-Jing Gao et al.   Neurotherapeutics

Differential mediation of descending pain facilitation and inhibition by spinal 5HT-3 and 5HT-7 receptors

(2009) Ahmet Dogrul et al.   BRAIN RESEARCH

Facilitatory Actions of Serotonin Type 3 Receptors on GABAergic Inhibitory Synaptic Transmission in the Spinal Superficial Dorsal Horn

(2009) Teruyuki Fukushima et al.   JOURNAL OF NEUROPHYSIOLOGY

The Liberation of Fractalkine in the Dorsal Horn Requires Microglial Cathepsin S

(2009) A. K. Clark et al.   JOURNAL OF NEUROSCIENCE

The Antiallodynic Effect of Neurotropin® Is Mediated via Activation of Descending Pain Inhibitory Systems in Rats with Spinal Nerve Ligation

(2008) Ryohei Okazaki et al.   ANESTHESIA AND ANALGESIA

Neuron–glia crosstalk gets serious: role in pain hypersensitivity

(2008) Ke Ren et al.   Current Opinion in Anesthesiology

Glia in pathological pain: A role for fractalkine

(2008) E.D. Milligan et al.   JOURNAL OF NEUROIMMUNOLOGY

Interleukin-18-Mediated Microglia/Astrocyte Interaction in the Spinal Cord Enhances Neuropathic Pain Processing after Nerve Injury

(2008) K. Miyoshi et al.   JOURNAL OF NEUROSCIENCE

Supraspinal Glial-Neuronal Interactions Contribute to Descending Pain Facilitation

(2008) F. Wei et al.   JOURNAL OF NEUROSCIENCE

Cytokine Mechanisms of Central Sensitization: Distinct and Overlapping Role of Interleukin-1 , Interleukin-6, and Tumor Necrosis Factor-  in Regulating Synaptic and Neuronal Activity in the Superficial Spinal Cord

(2008) Y. Kawasaki et al.   JOURNAL OF NEUROSCIENCE

Descending Serotonergic Controls Regulate Inflammation-Induced Mechanical Sensitivity and Methyl-CpG-Binding Protein 2 Phosphorylation in the Rat Superficial Dorsal Horn

(2008) Sandrine M Géranton et al.   Molecular Pain

Pathological and protective roles of glia in chronic pain

(2008) Erin D. Milligan et al.   NATURE REVIEWS NEUROSCIENCE

Interleukin 1β facilitates bone cancer pain in rats by enhancing NMDA receptor NR-1 subunit phosphorylation

(2008) R.-X. Zhang et al.   NEUROSCIENCE

5-HT3A receptor subunit is expressed in a subpopulation of GABAergic and enkephalinergic neurons in the mouse dorsal spinal cord

(2008) Jing Huang et al.   NEUROSCIENCE LETTERS