L1CAM promotes enrichment of immunosuppressive T cells in human pancreatic cancer correlating with malignant progression

CD69+CD4+CD25- T Cells, a New Subset of Regulatory T Cells, Suppress T Cell Proliferation through Membrane-Bound TGF- 1

(2014) Y. Han et al.   JOURNAL OF IMMUNOLOGY

Disruption of CCR5-Dependent Homing of Regulatory T Cells Inhibits Tumor Growth in a Murine Model of Pancreatic Cancer

(2014) M. C. B. Tan et al.   JOURNAL OF IMMUNOLOGY

Comparative Characterization of Stroma Cells and Ductal Epithelium in Chronic Pancreatitis and Pancreatic Ductal Adenocarcinoma

(2014) Ole Helm et al.   PLoS One

Cancer statistics, 2013

(2013) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Combined treatment of L1CAM antibodies and cytostatic drugs improve the therapeutic response of pancreatic and ovarian carcinoma

(2011) Heiner Schäfer et al.   CANCER LETTERS

Myofibroblast-induced tumorigenicity of pancreatic ductal epithelial cells is L1CAM dependent

(2011) Heiner Schäfer et al.   CARCINOGENESIS

Tumor-induced changes in the phenotype of blood-derived and tumor-associated T cells of early stage breast cancer patients

(2011) I. Poschke et al.   INTERNATIONAL JOURNAL OF CANCER

Increased CD4+CD69+CD25- T cells in patients with hepatocellular carcinoma are associated with tumor progression

(2011) Jiankang Zhu et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Cancer Exosomes Express CD39 and CD73, Which Suppress T Cells through Adenosine Production

(2011) A. Clayton et al.   JOURNAL OF IMMUNOLOGY

Pancreatic Cancer Alters Human CD4+ T Lymphocyte Function

(2011) Paola Fogar et al.   PANCREAS

Circulating CD4+CD25+ Regulatory T Cells in Patients With Pancreatic Cancer

(2011) Tomohisa Yamamoto et al.   PANCREAS

Positive Expression of L1-CAM is Associated with Perineural Invasion and Poor Outcome in Pancreatic Ductal Adenocarcinoma

(2010) Qi-Wen Ben et al.   ANNALS OF SURGICAL ONCOLOGY

L1CAM–integrin interaction induces constitutive NF-κB activation in pancreatic adenocarcinoma cells by enhancing IL-1β expression

(2010) H Kiefel et al.   ONCOGENE

Tumor-Derived Microvesicles Induce, Expand and Up-Regulate Biological Activities of Human Regulatory T Cells (Treg)

(2010) Marta Szajnik et al.   PLoS One

Nuclear translocation and signalling of L1-CAM in human carcinoma cells requires ADAM10 and presenilin/γ-secretase activity

(2009) Svenja Riedle et al.   BIOCHEMICAL JOURNAL

Up-regulation of L1CAM in Pancreatic Duct Cells Is Transforming Growth Factor  1- and Slug-Dependent: Role in Malignant Transformation of Pancreatic Cancer

(2009) C. Geismann et al.   CANCER RESEARCH

Chronic Pancreatitis Is Associated With Disease-Specific Regulatory T-Cell Responses

(2009) Hubertus Schmitz–Winnenthal et al.   GASTROENTEROLOGY

CD49d provides access to "untouched" human Foxp3+ Treg free of contaminating effector cells

(2008) M. Kleinewietfeld et al.   BLOOD

Role of myofibroblasts in innate chemoresistance of pancreatic carcinoma-Epigenetic downregulation of caspases

(2008) Susanne Sebens Müerköster et al.   INTERNATIONAL JOURNAL OF CANCER

Tumor-derived TGF-β Mediates Conversion of CD4+Foxp3+ Regulatory T Cells in a Murine Model of Pancreas Cancer

(2008) Tricia A. Moo-Young et al.   JOURNAL OF IMMUNOTHERAPY