Andrographolide reduces cognitive impairment in young and mature AβPPswe/PS-1 mice

Phosphorylation of Threonine-19 of PSD-95 by GSK-3  is Required for PSD-95 Mobilization and Long-Term Depression

(2013) C. D. Nelson et al.   JOURNAL OF NEUROSCIENCE

Selectively Silencing GSK-3 Isoforms Reduces Plaques and Tangles in Mouse Models of Alzheimer's Disease

(2012) D. E. Hurtado et al.   JOURNAL OF NEUROSCIENCE

The complex world of WNT receptor signalling

(2012) Christof Niehrs   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A novel role of andrographolide, an NF-kappa B inhibitor, on inhibition of platelet activation: the pivotal mechanisms of endothelial nitric oxide synthase/cyclic GMP

(2011) Wan-Jung Lu et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Recent rodent models for Alzheimer’s disease: clinical implications and basic research

(2011) Nady Braidy et al.   JOURNAL OF NEURAL TRANSMISSION

Aβ1–42 inhibition of LTP is mediated by a signaling pathway involving caspase-3, Akt1 and GSK-3β

(2011) Jihoon Jo et al.   NATURE NEUROSCIENCE

Neuroprotective effects of andrographolide in a rat model of permanent cerebral ischaemia

(2010) Su Jing Chan et al.   BRITISH JOURNAL OF PHARMACOLOGY

Neuroprotective strategies involving ROS in Alzheimer disease

(2010) Magali Dumont et al.   FREE RADICAL BIOLOGY AND MEDICINE

Wnt-5a occludes Aβ oligomer-induced depression of glutamatergic transmission in hippocampal neurons

(2010) Waldo Cerpa et al.   Molecular Neurodegeneration

Amyloid-β–induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks

(2010) Jorge J Palop et al.   NATURE NEUROSCIENCE

Wingless-type family member 5A (Wnt-5a) stimulates synaptic differentiation and function of glutamatergic synapses

(2010) L. Varela-Nallar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oxidative stress in the brain of nicotine-induced toxicity: protective role of Andrographis paniculata Nees and vitamin E

(2009) Subhasis Das et al.   Applied Physiology Nutrition and Metabolism

Alzheimer's disease: synaptic dysfunction and Aβ

(2009) Ganesh M Shankar et al.   Molecular Neurodegeneration

Emerging roles of Wnts in the adult nervous system

(2009) Nibaldo C. Inestrosa et al.   NATURE REVIEWS NEUROSCIENCE

Soluble Oligomers of Amyloid β Protein Facilitate Hippocampal Long-Term Depression by Disrupting Neuronal Glutamate Uptake

(2009) Shaomin Li et al.   NEURON

The relationship between episodic long-term memory and white matter integrity in normal aging

(2009) R.A. Charlton et al.   NEUROPSYCHOLOGIA

STI571 prevents apoptosis, tau phosphorylation and behavioural impairments induced by Alzheimer's β-amyloid deposits

(2008) Gonzalo I. Cancino et al.   BRAIN

Release of acetylcholinesterase (AChE) from β-amyloid plaques assemblies improves the spatial memory impairments in APP-transgenic mice

(2008) Margarita C. Dinamarca et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Structure-Function Implications in Alzheimers Disease: Effect of Aβ Oligomers at Central Synapses

(2008) Waldo Cerpa et al.   Current Alzheimer Research

Andrographolide reduces IL-2 production in T-cells by interfering with NFAT and MAPK activation

(2008) María D. Carretta et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

(2008) Ganesh M Shankar et al.   NATURE MEDICINE

GSK3 inhibitors show benefits in an Alzheimer's disease (AD) model of neurodegeneration but adverse effects in control animals

(2008) Shuxin Hu et al.   NEUROBIOLOGY OF DISEASE