Transgenic APP expression during postnatal development causes persistent locomotor hyperactivity in the adult

Spatial learning and memory impairment and increased locomotion in a transgenic amyloid precursor protein mouse model of Alzheimer's disease

(2011) J.M. Walker et al.   BEHAVIOURAL BRAIN RESEARCH

Medium spiny neurons of the neostriatal matrix exhibit specific, stereotyped changes in dendritic arborization during a critical developmental period in mice

(2011) Hyunchul Lee et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Robust Amyloid Clearance in a Mouse Model of Alzheimer's Disease Provides Novel Insights into the Mechanism of Amyloid-  Immunotherapy

(2011) A. Wang et al.   JOURNAL OF NEUROSCIENCE

Altered temporal patterns of anxiety in aged and amyloid precursor protein (APP) transgenic mice

(2011) T. A. Bedrosian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Increased aggression in males in transgenic Tg2576 mouse model of Alzheimer's disease

(2010) Gaukhman Alexander et al.   BEHAVIOURAL BRAIN RESEARCH

Ciproxifan, an H3 receptor antagonist, alleviates hyperactivity and cognitive deficits in the APPTg2576 mouse model of Alzheimer’s disease

(2010) Mark E. Bardgett et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Beta amyloid-independent role of amyloid precursor protein in generation and maintenance of dendritic spines

(2010) K.J. Lee et al.   NEUROSCIENCE

Intraneuronal β-Amyloid Accumulation in the Amygdala Enhances Fear and Anxiety in Alzheimer's Disease Transgenic Mice

(2009) Judit España et al.   BIOLOGICAL PSYCHIATRY

 -Secretase Inhibition Reduces Spine Density In Vivo via an Amyloid Precursor Protein-Dependent Pathway

(2009) T. Bittner et al.   JOURNAL OF NEUROSCIENCE

Presynaptic and Postsynaptic Interaction of the Amyloid Precursor Protein Promotes Peripheral and Central Synaptogenesis

(2009) Z. Wang et al.   JOURNAL OF NEUROSCIENCE

FAD-mutation of APP is associated with a loss of its synaptotrophic activity

(2009) Gudrun Seeger et al.   NEUROBIOLOGY OF DISEASE

Amyloid Plaque and Neurofibrillary Tangle Pathology in a Regulatable Mouse Model of Alzheimer's Disease

(2008) Jennifer B. Paulson et al.   AMERICAN JOURNAL OF PATHOLOGY

Secreted APP regulates the function of full-length APP in neurite outgrowth through interaction with integrin beta1

(2008) Tracy L Young-Pearse et al.   Neural Development

Behavioral Phenotyping Strategies for Mutant Mice

(2008) Jacqueline N. Crawley   NEURON