AT2R Activation Prevents Microglia Pro-inflammatory Activation in a NOX-Dependent Manner: Inhibition of PKC Activation and p47phox Phosphorylation by PP2A

Brain Renin-Angiotensin System and Microglial Polarization: Implications for Aging and Neurodegeneration

(2017) Jose L. Labandeira-Garcia et al.   Frontiers in Aging Neuroscience

Electron transport chain inhibitors induce microglia activation through enhancing mitochondrial reactive oxygen species production

(2016) Junli Ye et al.   EXPERIMENTAL CELL RESEARCH

Stimulation of the cardiac myocyte Na+-K+ pump due to reversal of its constitutive oxidative inhibition

(2015) Karin K. M. Chia et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Microglial M1/M2 polarization and metabolic states

(2015) Ruben Orihuela et al.   BRITISH JOURNAL OF PHARMACOLOGY

NOD2 activation induces oxidative stress contributing to mitochondrial dysfunction and insulin resistance in skeletal muscle cells

(2015) Chandan K. Maurya et al.   FREE RADICAL BIOLOGY AND MEDICINE

Angiotensin Receptor Blockade Modulates NFκB and STAT3 Signaling and Inhibits Glial Activation and Neuroinflammation Better than Angiotensin-Converting Enzyme Inhibition

(2015) Shahnawaz Ali Bhat et al.   MOLECULAR NEUROBIOLOGY

Redox Control of Microglial Function: Molecular Mechanisms and Functional Significance

(2014) Ana I. Rojo et al.   ANTIOXIDANTS & REDOX SIGNALING

The Protective Arms of the Renin-Angiontensin System in Stroke

(2014) Claudia A. McCarthy et al.   CURRENT HYPERTENSION REPORTS

Interaction between NADPH-oxidase and Rho-kinase in angiotensin II-induced microglial activation

(2014) Ana I. Rodriguez-Perez et al.   GLIA

Microglial and macrophage polarization—new prospects for brain repair

(2014) Xiaoming Hu et al.   Nature Reviews Neurology

Oxidative Stress and Neurodegenerative Disorders

(2013) Jie Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Protein Phosphatase 2A Is Regulated by Protein Kinase Cα (PKCα)-dependent Phosphorylation of Its Targeting Subunit B56α at Ser41

(2013) Uwe Kirchhefer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cellular and temporal expression of NADPH oxidase (NOX) isotypes after brain injury

(2013) Sean J Cooney et al.   Journal of Neuroinflammation

Cholesterol Diet Withdrawal Leads to an Initial Plaque Instability and Subsequent Regression of Accelerated Iliac Artery Atherosclerosis in Rabbits

(2013) Vivek Khanna et al.   PLoS One

Angiotensin II-Induced Production of Mitochondrial Reactive Oxygen Species: Potential Mechanisms and Relevance for Cardiovascular Disease

(2012) Sergey I. Dikalov et al.   ANTIOXIDANTS & REDOX SIGNALING

Angiotensin II AT1receptor blockers as treatments for inflammatory brain disorders

(2012) Juan M. Saavedra   CLINICAL SCIENCE

Mitochondria Sentencing About Cellular Life and Death: A Matter of Oxidative Stress

(2012) Nadezda Apostolova et al.   CURRENT PHARMACEUTICAL DESIGN

Transformation from a neuroprotective to a neurotoxic microglial phenotype in a mouse model of ALS

(2012) Bing Liao et al.   EXPERIMENTAL NEUROLOGY

Mechanism of Oxidative Stress in Neurodegeneration

(2012) Sonia Gandhi et al.   Oxidative Medicine and Cellular Longevity

Macrophage Polarization by Angiotensin II-Type 1 Receptor Aggravates Renal Injury-Acceleration of Atherosclerosis

(2011) Suguru Yamamoto et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Central angiotensin converting enzyme facilitates memory impairment in intracerebroventricular streptozotocin treated rats

(2011) Santoshkumar Tota et al.   BEHAVIOURAL BRAIN RESEARCH

Inhibition of NADPH oxidase promotes alternative and anti-inflammatory microglial activation during neuroinflammation

(2011) Sang-Ho Choi et al.   JOURNAL OF NEUROCHEMISTRY

Specific PKC isoforms regulate LPS-stimulated iNOS induction in murine microglial cells

(2011) Jie Wen et al.   Journal of Neuroinflammation

Flipping the switches: CD40 and CD45 modulation of microglial activation states in HIV associated dementia (HAD)

(2011) Jon Salemi et al.   Molecular Neurodegeneration

Mechanisms Underlying Inflammation in Neurodegeneration

(2010) Christopher K. Glass et al.   CELL

Translocator protein (18 kDa)/peripheral benzodiazepine receptor specific ligands induce microglia functions consistent with an activated state

(2010) Judy Choi et al.   GLIA

Microglia in neurodegenerative disease

(2010) V. Hugh Perry et al.   Nature Reviews Neurology

Glycogen synthase kinase-3 and p38 MAPK are required for opioid-induced microglia apoptosis

(2010) Nanchang Xie et al.   NEUROPHARMACOLOGY

Angiotensin II AT1 Receptor Blockade Ameliorates Brain Inflammation

(2010) Julius Benicky et al.   NEUROPSYCHOPHARMACOLOGY

Oxidative Stress and Neurodegenerative Diseases: A Review of Upstream and Downstream Antioxidant Therapeutic Options

(2009) Bayani Uttara et al.   Current Neuropharmacology

Nrf2 regulates microglial dynamics and neuroinflammation in experimental Parkinson's disease

(2009) Ana I. Rojo et al.   GLIA

Neurochemical and behavioral alterations in an inflammatory model of depression: Sex differences exposed

(2009) P.M. Pitychoutis et al.   NEUROSCIENCE

Angiotensin AT 2 Receptor Stimulation Causes Neuroprotection in a Conscious Rat Model of Stroke

(2009) Claudia A. McCarthy et al.   STROKE

Neuro-inflammation induced by lipopolysaccharide causes cognitive impairment through enhancement of beta-amyloid generation

(2008) Jae Lee et al.   Journal of Neuroinflammation

Brain angiotensin enhances dopaminergic cell death via microglial activation and NADPH-derived ROS

(2008) J. Rodriguez-Pallares et al.   NEUROBIOLOGY OF DISEASE

Expression of angiotensin II and its receptors in the normal and hypoxic amoeboid microglial cells and murine BV-2 cells

(2008) J.J. Li et al.   NEUROSCIENCE

Behavioral effects of LPS in adult, middle-aged and aged mice

(2008) Denise Kinoshita et al.   PHYSIOLOGY & BEHAVIOR