c-Abl Tyrosine Kinase Mediates Neurotoxic Prion Peptide-Induced Neuronal Apoptosis via Regulating Mitochondrial Homeostasis

Inhibition of phagocytosis reduced the classical activation of BV2 microglia induced by amyloidogenic fragments of beta-amyloid and prion proteins

(2013) F. Shi et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Parkinson’s Disease: A Complex Interplay of Mitochondrial DNA Alterations and Oxidative Stress

(2013) Sarah Ciccone et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cellular Prion Protein (PrPC) of the Neuron Cell Transformed to a PK-Resistant Protein Under Oxidative Stress, Comprising Main Mitochondrial Damage in Prion Diseases

(2013) Fangzhong Yuan et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Optic atrophy 1 mediates mitochondria remodeling and dopaminergic neurodegeneration linked to complex I deficiency

(2012) D Ramonet et al.   CELL DEATH AND DIFFERENTIATION

Apoptosis-induced mitochondrial dysfunction causes cytoplasmic lipid droplet formation

(2012) J Boren et al.   CELL DEATH AND DIFFERENTIATION

Targeting the Regulatory Machinery of BIM for Cancer Therapy

(2012) Hisashi Harada et al.   CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION

Neuronal autophagy and neurodegenerative diseases

(2012) Jin H. Son et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Melatonin-induced autophagy protects against human prion protein-mediated neurotoxicity

(2012) Jae-Kyo Jeong et al.   JOURNAL OF PINEAL RESEARCH

Regulation of Chaperone Effects on a Yeast Prion by Cochaperone Sgt2

(2012) D. A. Kiktev et al.   MOLECULAR AND CELLULAR BIOLOGY

Autophagy induced by the class III histone deacetylase Sirt1 prevents prion peptide neurotoxicity

(2012) Jae-Kyo Jeong et al.   NEUROBIOLOGY OF AGING

Autophagy induced by resveratrol prevents human prion protein-mediated neurotoxicity

(2012) Jae-Kyo Jeong et al.   NEUROSCIENCE RESEARCH

Selective Targeting of c-Abl via a Cryptic Mitochondrial Targeting Signal Activated by Cellular Redox Status in Leukemic and Breast Cancer Cells

(2012) Jonathan E. Constance et al.   PHARMACEUTICAL RESEARCH

BCL2A1: the underdog in the BCL2 family

(2011) M Vogler   CELL DEATH AND DIFFERENTIATION

Cell death pathways and autophagy in the central nervous system and its involvement in neurodegeneration, immunity and central nervous system infection: to die or not to die - that is the question

(2011) A. Rosello et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

c-Abl in Neurodegenerative Disease

(2011) Sarah D. Schlatterer et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

The c-Abl-MST1 Signaling Pathway Mediates Oxidative Stress-Induced Neuronal Cell Death

(2011) L. Xiao et al.   JOURNAL OF NEUROSCIENCE

Prions

(2011) D. W. Colby et al.   Cold Spring Harbor Perspectives in Biology

Thioflavine T interaction with synthetic Alzheimer's disease β-amyloid peptides: Detection of amyloid aggregation in solution

(2010) Harry Levine   PROTEIN SCIENCE

The effects of c-Abl mutation on developing B cell differentiation and survival

(2009) Hans Brightbill et al.   INTERNATIONAL IMMUNOLOGY

Regulation of Neuronal Cell Death by MST1-FOXO1 Signaling

(2009) Zengqiang Yuan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Local control of mitochondrial membrane potential, permeability transition pore and reactive oxygen species by calcium and calmodulin in rat ventricular myocytes

(2009) Keiichi Odagiri et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

c-Abl tyrosine kinase modulates tau pathology and Cdk5 phosphorylation in AD transgenic mice

(2009) Gonzalo I. Cancino et al.   NEUROBIOLOGY OF AGING

PrP(106-126) Does Not Interact with Membranes under Physiological Conditions

(2008) Sónia Troeira Henriques et al.   BIOPHYSICAL JOURNAL

STI571 prevents apoptosis, tau phosphorylation and behavioural impairments induced by Alzheimer's β-amyloid deposits

(2008) Gonzalo I. Cancino et al.   BRAIN

Prion Proteins Leading to Neurodegeneration

(2008) D. Mendola et al.   Current Alzheimer Research

Prion Protein Functions and Dysfunction in Prion Diseases

(2008) Akikazu Sakudo et al.   CURRENT MEDICINAL CHEMISTRY

Oxidative stress caused by blocking of mitochondrial Complex I H+ pumping as a link in aging/disease vicious cycle

(2008) Andrea Dlasková et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Cooperative Roles of c-Abl and Cdk5 in Regulation of p53 in Response to Oxidative Stress

(2008) Jong-Hee Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The PKC  -Abl complex communicates ER stress to the mitochondria - an essential step in subsequent apoptosis

(2008) X. Qi et al.   JOURNAL OF CELL SCIENCE