Synergy of Homocysteine, MicroRNA, and Epigenetics: A Novel Therapeutic Approach for Stroke

Genetically Engineered Microvesicles Carrying Suicide mRNA/Protein Inhibit Schwannoma Tumor Growth

(2012) Arda Mizrak et al.   MOLECULAR THERAPY

Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

(2011) Lydia Alvarez-Erviti et al.   NATURE BIOTECHNOLOGY

A Comprehensive Association Analysis of Homocysteine Metabolic Pathway Genes in Singaporean Chinese with Ischemic Stroke

(2011) Hui-Qi Low et al.   PLoS One

Emerging Role of Epigenetics in Stroke

(2010) Irfan A. Qureshi et al.   ARCHIVES OF NEUROLOGY

ANRIL Expression Is Associated With Atherosclerosis Risk at Chromosome 9p21

(2010) Lesca M. Holdt et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Role of histone acetylation in the activity-dependent regulation of sulfiredoxin and sestrin 2

(2010) Francesc X. Soriano et al.   Epigenetics

Alteration of thrombospondin-1 and -2 in rat brains following experimental intracerebral hemorrhage

(2010) Hua-Jun Zhou et al.   JOURNAL OF NEUROSURGERY

Targeted deletion of the 9p21 non-coding coronary artery disease risk interval in mice

(2010) Axel Visel et al.   NATURE

Mitochondrial Encephalopathy, Lactic Acidosis, and Strokelike Episodes

(2009) Douglas M. Sproule et al.   Annals of the New York Academy of Sciences

Functional Analysis of the Chromosome 9p21.3 Coronary Artery Disease Risk Locus

(2009) Olga Jarinova et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

RNA regulation of epigenetic processes

(2009) John S. Mattick et al.   BIOESSAYS

Global and regional causes of death

(2009) C. D. Mathers et al.   BRITISH MEDICAL BULLETIN

Phase I Study of MG98, an Oligonucleotide Antisense Inhibitor of Human DNA Methyltransferase 1, Given as a 7-Day Infusion in Patients with Advanced Solid Tumors

(2009) R. Plummer et al.   CLINICAL CANCER RESEARCH

Epigenetic Therapeutics in Autoimmune Disease

(2009) Moshe Szyf   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

High plasma homocysteine levels contribute to the risk of stroke recurrence and all-cause mortality in a large prospective stroke population

(2009) Weili Zhang et al.   CLINICAL SCIENCE

Fine-tuning neural gene expression with microRNAs

(2009) Gerhard Schratt   CURRENT OPINION IN NEUROBIOLOGY

Transient Focal Ischemia Induces Extensive Temporal Changes in Rat Cerebral MicroRNAome

(2009) Ashuthosh Dharap et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Regulation of Oestrogen Receptor Gene Expression: New Insights and Novel Mechanisms

(2009) M. E. Wilson et al.   JOURNAL OF NEUROENDOCRINOLOGY

Homocystine Levels, Polymorphisms and the Risk of Ischemic Stroke in Young Asian Indians

(2009) Arijit Biswas et al.   Journal of Stroke & Cerebrovascular Diseases

Epigenetic side-effects of common pharmaceuticals: A potential new field in medicine and pharmacology

(2009) Antonei B. Csoka et al.   MEDICAL HYPOTHESES

Recent progress in the biology and physiology of sirtuins

(2009) Toren Finkel et al.   NATURE

The logic of chromatin architecture and remodelling at promoters

(2009) Bradley R. Cairns   NATURE

The endogenous inhibitor of Akt, CTMP, is critical to ischemia-induced neuronal death

(2009) Takahiro Miyawaki et al.   NATURE NEUROSCIENCE

Epigenetic mechanisms that underpin metabolic and cardiovascular diseases

(2009) Peter D. Gluckman et al.   Nature Reviews Endocrinology

Long non-coding RNAs: insights into functions

(2009) Tim R. Mercer et al.   NATURE REVIEWS GENETICS

Regulation of non-coding RNA networks in the nervous system—What's the REST of the story?

(2009) Irfan A. Qureshi et al.   NEUROSCIENCE LETTERS

INK4/ARF Transcript Expression Is Associated with Chromosome 9p21 Variants Linked to Atherosclerosis

(2009) Yan Liu et al.   PLoS One

Genome-Wide Identification of Human RNA Editing Sites by Parallel DNA Capturing and Sequencing

(2009) J. B. Li et al.   SCIENCE

Targeting Histone Deacetylases as a Multifaceted Approach to Treat the Diverse Outcomes of Stroke

(2009) Brett Langley et al.   STROKE

Identification of a Shared Genetic Susceptibility Locus for Coronary Heart Disease and Periodontitis

(2009) Arne S. Schaefer et al.   PLoS Genetics

Transcriptional regulation of cholesterol 24-hydroxylase by histone deacetylase inhibitors

(2008) Marjan Shafaati et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Potential role of curcumin in stroke prevention

(2008) Bruce Ovbiagele   Expert Review of Neurotherapeutics

GNAS Defects Identified by Stimulatory G Protein α-Subunit Signalling Studies in Platelets

(2008) Kathleen Freson et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Intracerebral transplantation of human adipose tissue stromal cells after middle cerebral artery occlusion in rats

(2008) Tae-Hoon Lee et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Involvement of Src Tyrosine Kinases (SFKs) and of Focal Adhesion Kinase (FAK) in the Injurious Mechanism in Rat Primary Neuronal Cultures Exposed to Chemical Ischemia

(2008) Vered Shani et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Stroke

(2008) Geoffrey A Donnan et al.   LANCET

Induced ncRNAs allosterically modify RNA-binding proteins in cis to inhibit transcription

(2008) Xiangting Wang et al.   NATURE

Frequency and fate of microRNA editing in human brain

(2008) Y. Kawahara et al.   NUCLEIC ACIDS RESEARCH

Epigenetic principles and mechanisms underlying nervous system functions in health and disease

(2008) M MEHLER   PROGRESS IN NEUROBIOLOGY

Experimental identification of microRNA-140 targets by silencing and overexpressing miR-140

(2008) F. E. Nicolas et al.   RNA

MicroRNA Expression in the Blood and Brain of Rats Subjected to Transient Focal Ischemia by Middle Cerebral Artery Occlusion

(2008) Kandiah Jeyaseelan et al.   STROKE