Pax6-Dependent Cortical Glutamatergic Neuronal Differentiation Regulates Autism-Like Behavior in Prenatally Valproic Acid-Exposed Rat Offspring

Progress toward treatments for synaptic defects in autism

(2013) Richard Delorme et al.   NATURE MEDICINE

Targeting the endocannabinoid system in the treatment of fragile X syndrome

(2013) Arnau Busquets-Garcia et al.   NATURE MEDICINE

Lovastatin Corrects Excess Protein Synthesis and Prevents Epileptogenesis in a Mouse Model of Fragile X Syndrome

(2013) Emily K. Osterweil et al.   NEURON

Epigenetic changes and disturbed neural development in a human embryonic stem cell-based model relating to the fetal valproate syndrome

(2012) Nina V. Balmer et al.   HUMAN MOLECULAR GENETICS

Memantine as adjunctive treatment to risperidone in children with autistic disorder: a randomized, double-blind, placebo-controlled trial

(2012) Ali Ghaleiha et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Chronic Pharmacological mGlu5 Inhibition Corrects Fragile X in Adult Mice

(2012) Aubin Michalon et al.   NEURON

Prenatal exposure to valproic acid increases the neural progenitor cell pool and induces macrocephaly in rat brain via a mechanism involving the GSK-3β/β-catenin pathway

(2012) Hyo Sang Go et al.   NEUROPHARMACOLOGY

The Therapeutic effect of Memantine through the Stimulation of Synapse Formation and Dendritic Spine Maturation in Autism and Fragile X Syndrome

(2012) Hongen Wei et al.   PLoS One

Elevated Glutamatergic Compounds in Pregenual Anterior Cingulate in Pediatric Autism Spectrum Disorder Demonstrated by 1H MRS and 1H MRSI

(2012) Anthony Bejjani et al.   PLoS One

Reversal of Disease-Related Pathologies in the Fragile X Mouse Model by Selective Activation of GABAB Receptors with Arbaclofen

(2012) C. Henderson et al.   Science Translational Medicine

Absence of CNTNAP2 Leads to Epilepsy, Neuronal Migration Abnormalities, and Core Autism-Related Deficits

(2011) Olga Peñagarikano et al.   CELL

Neocortical excitation/inhibition balance in information processing and social dysfunction

(2011) Ofer Yizhar et al.   NATURE

Altered object-in-place recognition memory, prepulse inhibition, and locomotor activity in the offspring of rats exposed to a viral mimetic during pregnancy

(2011) J.G. Howland et al.   NEUROSCIENCE

Schizophrenia and Autism: Both Shared and Disorder-Specific Pathogenesis Via Perinatal Inflammation?

(2011) URS MEYER et al.   PEDIATRIC RESEARCH

Reversal of Fragile X Phenotypes by Manipulation of AβPP/Aβ Levels in Fmr1KO Mice

(2011) Cara J. Westmark et al.   PLoS One

mGluR5-Antagonist Mediated Reversal of Elevated Stereotyped, Repetitive Behaviors in the VPA Model of Autism

(2011) Mili V. Mehta et al.   PLoS One

The Generation of Superficial Cortical Layers Is Regulated by Levels of the Transcription Factor Pax6

(2010) Petrina A. Georgala et al.   CEREBRAL CORTEX

Deacetylase Inhibitors Dissociate the Histone-Targeting ING2 Subunit from the Sin3 Complex

(2010) Karen T. Smith et al.   CHEMISTRY & BIOLOGY

Expression of the Hippocampal NMDA Receptor GluN1 Subunit and Its Splicing Isoforms in Schizophrenia: Postmortem Study

(2010) Monika Vrajová et al.   NEUROCHEMICAL RESEARCH

Evaluation of Pax6 Mutant Rat as a Model for Autism

(2010) Toshiko Umeda et al.   PLoS One

The critical period of valproate exposure to induce autistic symptoms in Sprague–Dawley rats

(2010) Ki Chan Kim et al.   TOXICOLOGY LETTERS

Increased dendritic spine densities on cortical projection neurons in autism spectrum disorders

(2009) Jeffrey J. Hutsler et al.   BRAIN RESEARCH

Histone Deacetylase Inhibitor Induction of P-Glycoprotein Transcription Requires Both Histone Deacetylase 1 Dissociation and Recruitment of CAAT/Enhancer Binding Protein   and pCAF to the Promoter Region

(2009) S.-N. Kim et al.   MOLECULAR CANCER RESEARCH

Semaphorin 5B mediates synapse elimination in hippocampal neurons

(2009) Timothy P O'Connor et al.   Neural Development

A novel missense mutation (Leu46Val) of PAX6 found in an autistic patient

(2009) Motoko Maekawa et al.   NEUROSCIENCE LETTERS

Behavior and serotonergic disorders in rats exposed prenatally to valproate: A model for autism

(2009) Diane Dufour-Rainfray et al.   NEUROSCIENCE LETTERS

The Role of Epilepsy and Epileptiform EEGs in Autism Spectrum Disorders

(2009) Sarah J Spence et al.   PEDIATRIC RESEARCH

Arachidonic Acid Drives Postnatal Neurogenesis and Elicits a Beneficial Effect on Prepulse Inhibition, a Biological Trait of Psychiatric Illnesses

(2009) Motoko Maekawa et al.   PLoS One

The Level of the Transcription Factor Pax6 Is Essential for Controlling the Balance between Neural Stem Cell Self-Renewal and Neurogenesis

(2009) Stephen N. Sansom et al.   PLoS Genetics

Immune involvement in schizophrenia and autism: Etiology, pathology and animal models

(2008) Paul H. Patterson   BEHAVIOURAL BRAIN RESEARCH

Effects of Disrupting Calcium Homeostasis on Neuronal Maturation: Early Inhibition and Later Recovery

(2008) Sarah L. Ringler et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Pax6 3′ deletion results in aniridia, autism and mental retardation

(2008) L. K. Davis et al.   HUMAN GENETICS

Reversal of learning deficits in a Tsc2 +/− mouse model of tuberous sclerosis

(2008) Dan Ehninger et al.   NATURE MEDICINE