Laforin–Malin Complex Degrades Polyglucosan Bodies in Concert with Glycogen Debranching Enzyme and Brain Isoform Glycogen Phosphorylase

Hyperphosphorylation of Glucosyl C6 Carbons and Altered Structure of Glycogen in the Neurodegenerative Epilepsy Lafora Disease

(2013) Felix Nitschke et al.   Cell Metabolism

Laforin Prevents Stress-Induced Polyglucosan Body Formation and Lafora Disease Progression in Neurons

(2013) Yin Wang et al.   MOLECULAR NEUROBIOLOGY

Laforin is required for the functional activation of malin in endoplasmic reticulum stress resistance in neuronal cells

(2012) Li Zeng et al.   FEBS Journal

Increased Laforin and Laforin Binding to Glycogen Underlie Lafora Body Formation in Malin-deficient Lafora Disease

(2012) Erica Tiberia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphate Incorporation during Glycogen Synthesis and Lafora Disease

(2011) Vincent S. Tagliabracci et al.   Cell Metabolism

Neurodegeneration and functional impairments associated with glycogen synthase accumulation in a mouse model of Lafora disease

(2011) Jordi Valles-Ortega et al.   EMBO Molecular Medicine

Dysfunctions in endosomal–lysosomal and autophagy pathways underlie neuropathology in a mouse model for Lafora disease

(2011) Rajat Puri et al.   HUMAN MOLECULAR GENETICS

Laforin and malin knockout mice have normal glucose disposal and insulin sensitivity

(2011) Anna A. DePaoli-Roach et al.   HUMAN MOLECULAR GENETICS

Lafora bodies and neurological defects in malin-deficient mice correlate with impaired autophagy

(2011) Olga Criado et al.   HUMAN MOLECULAR GENETICS

Laforin, a dual specificity phosphatase involved in Lafora disease, regulates insulin response and whole-body energy balance in mice

(2011) Santiago Vernia et al.   HUMAN MOLECULAR GENETICS

Multiple Glycogen-binding Sites in Eukaryotic Glycogen Synthase Are Required for High Catalytic Efficiency toward Glycogen

(2011) Sulochanadevi Baskaran et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Laforin-Malin Complex Negatively Regulates Glycogen Synthesis by Modulating Cellular Glucose Uptake via Glucose Transporters

(2011) P. K. Singh et al.   MOLECULAR AND CELLULAR BIOLOGY

Glycogen hyperphosphorylation underlies lafora body formation

(2010) Julie Turnbull et al.   ANNALS OF NEUROLOGY

Allosteric Regulation of Glycogen Synthase Controls Glycogen Synthesis in Muscle

(2010) Michale Bouskila et al.   Cell Metabolism

Laforin, the most common protein mutated in Lafora disease, regulates autophagy

(2010) Carmen Aguado et al.   HUMAN MOLECULAR GENETICS

Genetic Depletion of the Malin E3 Ubiquitin Ligase in Mice Leads to Lafora Bodies and the Accumulation of Insoluble Laforin

(2010) Anna A. DePaoli-Roach et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Laforin–Malin Complex, Involved in Lafora Disease, Promotes the Incorporation of K63-linked Ubiquitin Chains into AMP-activated Protein Kinase β Subunits

(2010) Daniel Moreno et al.   MOLECULAR BIOLOGY OF THE CELL

Structural basis for glucose-6-phosphate activation of glycogen synthase

(2010) Sulochanadevi Baskaran et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct mutations in the glycogen debranching enzyme found in glycogen storage disease type III lead to impairment in diverse cellular functions

(2009) Alan Cheng et al.   HUMAN MOLECULAR GENETICS

AMP-activated Protein Kinase Phosphorylates R5/PTG, the Glycogen Targeting Subunit of the R5/PTG-Protein Phosphatase 1 Holoenzyme, and Accelerates Its Down-regulation by the Laforin-Malin Complex

(2009) Santiago Vernia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Abnormal Metabolism of Glycogen Phosphate as a Cause for Lafora Disease

(2008) Vincent S. Tagliabracci et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Laforin Negatively Regulates Cell Cycle Progression through Glycogen Synthase Kinase 3 -Dependent Mechanisms

(2008) R. Liu et al.   MOLECULAR AND CELLULAR BIOLOGY