Article
Multidisciplinary Sciences
Hao Zhang, Subash C. B. Gopinath, Yajun Hu
Summary: A spinal cord injury refers to damage to the nerves and cells that receive and provide signals from the brain, causing changes in movement, sensation, and strength, potentially leading to paralysis. This study developed an S100 protein immunoassay to diagnose spinal cord injury.
Article
Materials Science, Textiles
Karima Sahtani, Yakup Aykut, Nilay Aladag Tanik
Summary: The use of hemoglobin-assisted carbon nanofibers for selective detection of miRNA molecules showed promising results, with an increase in guanine oxidation signal levels observed. This enhanced signal level could be attributed to the catalytic effect of low hemoglobin addition during the carbonization process, leading to a higher graphitic level in the precursor nanofibers. The biosensory system developed could be utilized for the selective detection of miRNA molecules.
JOURNAL OF INDUSTRIAL TEXTILES
(2022)
Article
Chemistry, Analytical
Hao Wang, Hongmei Hua, Haoran Tang, Yongxin Li
Summary: A new nanosensor for glutathione (GSH) detection has been developed using single nanoelectrodes and a dual-signaling ratiometric amplification strategy. The sensor showed a linear relationship between the ratio of dual signals and GSH concentrations, making it suitable for GSH detection in living systems. The nanosensor is label-free, easy to operate, and eliminates inherent system errors.
ANALYTICA CHIMICA ACTA
(2021)
Article
Biochemical Research Methods
Baban Dey, Md. Wasi Ahmad, Bo Hye Kim, Tahseen Kamal, Duck-Joo Yang, Chandra N. Patra, S. K. Safdar Hossain, Arup Choudhury
Summary: In this study, a hybrid array based on manganese cobalt (2-methylimodazole)-metal organic frameworks (Mn-Co(2-MeIm)MOF) and carbon nanofibers (CNFs) was prepared as a non-enzymatic electrochemical sensor for histamine detection in fish and bananas. The hybrid array exhibited high porosity, large specific surface area, and excellent hydrophilicity, enabling easy access of analyte molecules to the redox-active metal sites of the MOF. The sensor demonstrated excellent electrocatalytic activity for histamine oxidation under acidic conditions, with a wide linear range, low limit of detection, and high sensitivity. Importantly, the sensor was capable of detecting histamine in fish and banana samples stored for different periods of time, indicating its practical viability as an analytical histamine detector.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2023)
Article
Multidisciplinary Sciences
Uikyu Chae, Jiwan Woo, Yakdol Cho, Jeong- Kyu Han, Soo Hyun Yang, Esther Yang, Hyogeun Shin, Hyun Kim, Hyun- Yong Yu, C. Justin Lee, Il-Joo Cho
Summary: Real-time monitoring of neurochemicals and electrical activity in the brain is essential for investigating neural circuits. We have developed a real-time bimodal neural probe that can simultaneously measure multiple neurochemicals without cross-talk and record electrical activity. Using this probe, we have demonstrated simultaneous measurements of glucose, lactate, choline, and glutamate, as well as functional connectivity between brain regions. This device has the potential to greatly enhance our understanding of neurochemicals in neural circuits and aid in the development of drugs for brain diseases.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2023)
Article
Biochemical Research Methods
Irem Okman Kocoglu, Pinar Esra Erden, Esma Kilic
Summary: In this study, an electrochemical biosensor based on carbon nanofibers and ionic liquid modification was constructed for tyramine detection. The biosensor showed linear response, low detection limit, high sensitivity, and exhibited good reproducibility, stability, and anti-interference ability.
ANALYTICAL BIOCHEMISTRY
(2024)
Article
Spectroscopy
Faten Bashar Kamal Eddin, Yap Wing Fen, Nur Alia Sheh Omar, Josephine Ying Chyi Liew, Wan Mohd Ebtisyam Mustaqim Mohd Daniyal
Summary: A SPR sensor based on chitosan-graphene quantum dots thin film has been developed for detecting dopamine concentrations in the range from 0 fM to 1 pM, showing high sensitivity and low detection limit. The sensor exhibits outstanding performance in dopamine detection, demonstrating high accuracy and potential for clinical diagnostic applications.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Nanoscience & Nanotechnology
Jagadeesh Suriyaprakash, Kanchan Bala, Lianwei Shan, Lijun Wu, Neeraj Gupta
Summary: In this study, p-aminophenol (PAP)-functionalized reduced graphene oxide (rGO) nanoscale material was developed as an all-organic-based sensor, showing outstanding sensing ability and fast electrical transduction. The physicochemical properties and interaction mechanism of analyte-material transduction were discussed using various analytical and density functional theory (DFT) calculation methods, providing new insights and pathways for developing other forms of metal-free/organic functionalized biosensors.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Engineering, Environmental
Jiaqi Zhang, Christopher Hurren, Zhentan Lu, Dong Wang
Summary: This research presents a simple nanofiber-based platform for highly sensitive colorimetric/fluorometric detection of Escherichia coli (E. coli) in complex environmental samples. The nanofiber membranes loaded with target molecules via chemical modification can produce biological signals and color change triggered by beta-glucuronidase secreted by E. coli. The nanofiber-based platforms exhibited high stability, a wide detection range, high specificity, and low interference, making them promising for environmental and food safety testing. The combination with a smartphone app enables on-site detection of E. coli.
CHEMICAL ENGINEERING JOURNAL
(2023)
Review
Chemistry, Analytical
Ziheng Hu, Yaqi Li, Gabriela Figueroa-Miranda, Simon Musall, Hangyu Li, Mateo Alejandro Martinez-Roque, Qinyu Hu, Lingyan Feng, Dirk Mayer, Andreas Offenhaeusser
Summary: Neurotransmitters control signal transmission in chemical synapses by being released from the pre-synaptic neuron and binding to receptors in the postsynaptic neuron. Measurement of neurotransmitter concentrations with high spatiotemporal resolution is essential for understanding brain function and dysfunction in neurological diseases. Aptamer based biosensors are a valuable tool in achieving this goal, offering advantages in tailoring receptors for specific tasks.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2023)
Article
Electrochemistry
Hamza Abdalla Yones, Lin Zhu, Bo Shao, Siyue Zhang, Hui Xie, Xiaoqing Li, Wei Sun
Summary: A MgO@CNFs nanocomposite was prepared and casted onto a carbon ionic liquid electrode, with hemoglobin immobilized by a Nafion polymer film. The modified electrode provided a favorable microenvironment for Hb, improving loading amount and electron transfer rate. The study demonstrated high electrocatalytic activity for the reduction of trichloroacetic acid, offering a novel approach for nanostructured biosurfaces in electrochemical biosensors.
INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE
(2021)
Article
Chemistry, Analytical
Akash Nathani, Yinghua Qi, Sunil K. Varshney, Chandra Shekhar Sharma
Summary: The study presents a synthesis of amphiphilic diblock copolymer for protein detection and fabrication of mesoporous thin film electrodes with ultra-low detection limit and enhanced selectivity, showcasing the potential of the platform as an ultrasensitive immunosensor for biomarker detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Physics, Fluids & Plasmas
Dingchen Li, Chuan Li, Jiawei Li, Menghan Xiao, Pengyu Wang, Zhi Liu, Ming Zhang, Yong Yang, Kexun Yu
Summary: The advent of nanoelectrodes has overcome the technical limitations of traditional electrodes, enabling low voltage corona discharges with nanometer-sized tips. However, research on the discharge characteristics of nanoelectrodes is still relatively sparse. This paper proposes a numerical simulation model based on the hybrid hydrodynamics model and ion migration model, and studies the corona discharge characteristics of an array of carbon nanotubes (ACNTs).
PLASMA SOURCES SCIENCE & TECHNOLOGY
(2023)
Review
Chemistry, Multidisciplinary
Yutong Du, Xinyi Zhang, Ping Liu, Deng-Guang Yu, Ruiliang Ge
Summary: This article reviews the applications of glucose sensors based on electrospun nanofibers. The principles, detection methods, and advantages of glucose sensors are discussed. The enzymatic and non-enzymatic nanofiber-based glucose sensors are compared and evaluated, and potential solutions are proposed.
FRONTIERS IN CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Gabrielle R. Dangel, Hope Kumakli, Connor E. Rahm, Ryan White, Noe T. Alvarez
Summary: The incorporation of carbon nanotubes (CNTs) and their assemblies into macroscopic materials is leading the way in scientific innovation. The fabrication of random arrays of CNT cross-sections and their performance as nanoelectrode ensembles (NEEs) allows for easier production of nanoscale electrodes with unique electrochemical properties. Surface analysis and electrochemical testing demonstrated the stable nature of NEEs and their high sensitivity and wide linear range in Pb2+ detection.
APPLIED SCIENCES-BASEL
(2021)