标题
BRAF-induced tumorigenesis is IKKα-dependent but NF-κB–independent
作者
关键词
-
出版物
Science Signaling
Volume 8, Issue 373, Pages ra38-ra38
出版商
American Association for the Advancement of Science (AAAS)
发表日期
2015-04-22
DOI
10.1126/scisignal.2005886
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Dual inhibition of autophagy and the AKT pathway in prostate cancer
- (2013) Francois Lamoureux et al. Autophagy
- Inhibition of vacuolar H+ ATPase enhances sensitivity to tamoxifen via up-regulation of CHOP in breast cancer cells
- (2013) Hyeon-Ok Jin et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Chromatin-Bound IκBα Regulates a Subset of Polycomb Target Genes in Differentiation and Cancer
- (2013) María Carmen Mulero et al. CANCER CELL
- RAF Inhibitors Activate the MAPK Pathway by Relieving Inhibitory Autophosphorylation
- (2013) Matthew Holderfield et al. CANCER CELL
- Mechanism of MEK inhibition determines efficacy in mutant KRAS- versus BRAF-driven cancers
- (2013) Georgia Hatzivassiliou et al. NATURE
- Panitumumab–FOLFOX4 Treatment and RAS Mutations in Colorectal Cancer
- (2013) Jean-Yves Douillard et al. NEW ENGLAND JOURNAL OF MEDICINE
- Resistance of colon cancer to 5-fluorouracil may be overcome by combination with chloroquine, an in vivo study
- (2012) Kazuhito Sasaki et al. ANTI-CANCER DRUGS
- KrasG12D-Induced IKK2/β/NF-κB Activation by IL-1α and p62 Feedforward Loops Is Required for Development of Pancreatic Ductal Adenocarcinoma
- (2012) Jianhua Ling et al. CANCER CELL
- TAK1 Inhibition Promotes Apoptosis in KRAS-Dependent Colon Cancers
- (2012) Anurag Singh et al. CELL
- Blocked Autophagy Using Lysosomotropic Agents Sensitizes Resistant Prostate Tumor Cells to the Novel Akt Inhibitor AZD5363
- (2012) F. Lamoureux et al. CLINICAL CANCER RESEARCH
- Ubiquitination in signaling to and activation of IKK
- (2012) Zhijian J. Chen IMMUNOLOGICAL REVIEWS
- Dabrafenib in BRAF-mutated metastatic melanoma: a multicentre, open-label, phase 3 randomised controlled trial
- (2012) Axel Hauschild et al. LANCET
- Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR
- (2012) Anirudh Prahallad et al. NATURE
- Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion
- (2012) Ravid Straussman et al. NATURE
- Combined BRAF and MEK Inhibition in Melanoma with BRAF V600 Mutations
- (2012) Keith T. Flaherty et al. NEW ENGLAND JOURNAL OF MEDICINE
- Survival in BRAF V600–Mutant Advanced Melanoma Treated with Vemurafenib
- (2012) Jeffrey A. Sosman et al. NEW ENGLAND JOURNAL OF MEDICINE
- Requirement of NEMO/IKKγ for effective expansion of KRAS-induced precancerous lesions in the pancreas
- (2012) H J Maier et al. ONCOGENE
- A Truncated Form of IKKα Is Responsible for Specific Nuclear IKK Activity in Colorectal Cancer
- (2012) Pol Margalef et al. Cell Reports
- TRAF6 is an amplified oncogene bridging the RAS and NF-κB pathways in human lung cancer
- (2011) Daniel T. Starczynowski et al. JOURNAL OF CLINICAL INVESTIGATION
- Kinase-Dead BRAF and Oncogenic RAS Cooperate to Drive Tumor Progression through CRAF
- (2010) Sonja J. Heidorn et al. CELL
- Wnt Signaling Requires Sequestration of Glycogen Synthase Kinase 3 inside Multivesicular Endosomes
- (2010) Vincent F. Taelman et al. CELL
- RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF
- (2010) Poulikos I. Poulikakos et al. NATURE
- RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth
- (2010) Georgia Hatzivassiliou et al. NATURE
- Requirement for NF-κB signalling in a mouse model of lung adenocarcinoma
- (2009) Etienne Meylan et al. NATURE
- Implications for KRAS status and EGFR-targeted therapies in metastatic CRC
- (2009) Nicola Normanno et al. Nature Reviews Clinical Oncology
- The Signaling Adaptor p62 Is an Important NF-κB Mediator in Tumorigenesis
- (2008) Angeles Duran et al. CANCER CELL
- Elevated CRAF as a Potential Mechanism of Acquired Resistance to BRAF Inhibition in Melanoma
- (2008) C. Montagut et al. CANCER RESEARCH
- K-rasMutations and Benefit from Cetuximab in Advanced Colorectal Cancer
- (2008) Christos S. Karapetis et al. NEW ENGLAND JOURNAL OF MEDICINE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started