Article
Nutrition & Dietetics
Haiyan Xu, Chen Ma, Feiyan Zhao, Ping Chen, Yahua Liu, Zhihong Sun, Lihong Cui, Lai-Yu Kwok, Heping Zhang
Summary: This study found that adjunctive use of probiotics with a routine regimen for IBS management showed additional clinical effectiveness compared to using the routine regimen alone. The probiotic adjunctive treatment significantly decreased IBS symptom severity score, levels of harmful bacterial genera, and levels of beneficial bacterial genera in IBS patients.
EUROPEAN JOURNAL OF NUTRITION
(2021)
Review
Nutrition & Dietetics
Robin Spiller
Summary: IBS is strongly influenced by diet, but identifying specific food intolerances is difficult due to the complexities of diet. Rapidly fermented carbohydrates and gut-specific mast cell activation may cause symptoms in IBS patients. More research is needed to fully understand the mechanisms of food intolerances and improve personalized medicine approaches to diet in IBS.
Article
Medicine, General & Internal
Samira Ait Abdellah, Julien Scanzi, Caroline Gal, Marc Martin, Marc Beck, Veronica Ojetti
Summary: This multicenter study investigated the effects of L. gasseri LA806 supplementation on IBS symptoms and quality of life. The study found that the majority of patients experienced a significant decrease in abdominal pain and improvement in overall IBS symptoms and quality of life after 4 weeks of supplementation.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Nutrition & Dietetics
Claudia Di Rosa, Annamaria Altomare, Vittoria Terrigno, Florencia Carbone, Jan Tack, Michele Cicala, Michele Pier Luca Guarino
Summary: Irritable bowel syndrome (IBS) is a chronic gastrointestinal disorder characterized by abdominal pain and altered bowel habits. The exact cause of IBS is not fully understood, but it is believed to involve a combination of factors such as abnormal gut motility, inflammation, increased intestinal permeability, and sensitivity. Diet and gut microbiota have also been identified as important contributors to IBS. This review examines the effects of dietary components, functional foods, prebiotics, probiotics, and symbiotics on symptoms and gut microbiota in individuals with IBS-C.
Article
Multidisciplinary Sciences
Chenxi Yan, Chenmin Hu, Xiaolong Chen, Xinyi Jia, Zhenya Zhu, Diya Ye, Yuhao Wu, Rui Guo, Mizu Jiang
Summary: This meta-analysis suggests that vitamin D supplementation may help alleviate gastrointestinal symptoms in patients with irritable bowel syndrome (IBS), but has no significant impact on quality of life.
Review
Microbiology
Tomasz Wollny, Tamara Daniluk, Ewelina Piktel, Urszula Wnorowska, Anna Buklaha, Katarzyna Gluszek, Bonita Durnas, Robert Bucki
Summary: Irritable bowel syndrome (IBS) is a common, chronic, functional disorder that impacts a large proportion of the world population, with its pathophysiology not fully understood. Emerging evidence suggests that gut microbiota plays a significant role in the development of IBS, and therefore targeting microbial modulation may effectively enhance therapy.
Review
Biochemistry & Molecular Biology
Agnieszka Chlebicz-Wojcik, Katarzyna Slizewska
Summary: Irritable bowel syndrome is not life-threatening but significantly impacts quality of life and economic loss. Research focuses on the role of intestinal microbiota in disease development, with an emphasis on therapies modulating the microbiota such as probiotics, prebiotics, and synbiotics. Most studies have focused on probiotics, but there are also promising results from studies on prebiotics and synbiotics.
Article
Microbiology
Julien Tap, Stine Storsrud, Boris Le Neve, Aurelie Cotillard, Nicolas Pons, Joel Dore, Lena Ohman, Hans Tornblom, Muriel Derrien, Magnus Simren
Summary: Individuals with severe IBS were found to have a higher intake of poorer-quality food items, and the covariations between gut microbiota at subspecies level and diet were associated with factors such as symptom severity. The study provides insight into diet-microbiota-symptom interactions and may guide future interventional studies on gut microbiome-based nutritional recommendations for managing gastrointestinal symptoms.
Review
Medicine, General & Internal
Mihaela Fadgyas Stanculete, Abdulrahman Ismaiel, Stefan-Lucian Popa, Octavia Oana Capatina
Summary: Irritable bowel syndrome (IBS) is a disorder characterized by altered gut-brain interaction and dysfunction of the brain-gut-microbiota axis. Prior studies have shown significant impairments in the health-related quality of life of patients with IBS. Resilience, as a psychosocial ability, plays a crucial role in promoting health and enhancing stress response.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Gastroenterology & Hepatology
Claire L. Jansson-Knodell, Mattie White, Carolyn Lockett, Huiping Xu, Andrea Shin
Summary: The type of food intolerance is associated with irritable bowel syndrome (IBS), anxiety, depression, and decreased health-related quality of life, often leading to food elimination. Adults with lactose and lactose plus food intolerance have higher rates of IBS, increased psychological symptoms, and poorer quality of life.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2022)
Article
Gastroenterology & Hepatology
Xiu-Cai Fang, Wen-Juan Fan, Douglas D. Drossman, Shao-Mei Han, Mei-Yun Ke
Summary: This study compared bowel symptoms and psychosocial features in IBS patients diagnosed with Rome III criteria with abdominal discomfort, abdominal pain, and pain & discomfort. The results showed that IBS patients with abdominal discomfort have similar bowel symptoms and psychosocial features to those with abdominal pain.
WORLD JOURNAL OF GASTROENTEROLOGY
(2022)
Review
Pharmacology & Pharmacy
Chao-Rong Xie, Bin Tang, Yun-Zhou Shi, Wen-Yan Peng, Kun Ye, Qing-Feng Tao, Shu-Guang Yu, Hui Zheng, Min Chen
Summary: This study evaluated the most effective approaches for managing irritable bowel syndrome (IBS) by analyzing different combinations and components of probiotics or a low FODMAP diet. The results showed that Lactobacillus was the most effective component for relieving IBS symptoms, while Bifidobacterium and Bacillus were potentially effective and require further verification.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Medicine, General & Internal
Cristina Tocia, Irina Magdalena Dumitru, Luana Alexandrescu, Lucian Cristian Petcu, Eugen Dumitru
Summary: This study demonstrates that rifaximin is effective in treating and improving irritable bowel syndrome-like symptoms in patients with Crohn's disease in remission, thereby enhancing their quality of life.
Article
Gastroenterology & Hepatology
Qi Su, Hein M. Tun, Qin Liu, Yun Kit Yeoh, Joyce Wing Yan Mak, Francis K. L. Chan, Siew C. Ng
Summary: This study examined the association between gut microbiota and Irritable bowel syndrome (IBS) subtypes, and found that there are distinct differences in microbiota composition among different IBS subtypes. The microbial diversity is significantly reduced in IBS-D and IBS-U, but not in IBS-C. The study also identified microbial signatures associated with depression in IBS patients. Factors such as gender, age, and dietary patterns have significant effects on gut microbiota in different IBS subtypes. These findings emphasize the importance of personalized gut microbiome modulation approaches for optimal therapeutic effects in different subtypes of IBS.
Article
Gastroenterology & Hepatology
Jean-Marc Sabate, Franck Iglicki
Summary: B. longum 35624 has a significant impact on the severity and quality of life of IBS patients in a real-life setting. After a 30-day treatment period, there was a significant decrease in IBS severity and an improvement in patient quality of life.
WORLD JOURNAL OF GASTROENTEROLOGY
(2022)