Functional human sperm capacitation requires both bicarbonate-dependent PKA activation and down-regulation of Ser/Thr phosphatases by Src family kinases

The CatSper channel: a polymodal chemosensor in human sperm

(2012) Christoph Brenker et al.   EMBO JOURNAL

Inhibition of sperm capacitation and fertilizing capacity by adjudin is mediated by chloride and its channels in humans

(2012) Kun Li et al.   HUMAN REPRODUCTION

Differential concentration and time dependent effects of progesterone on kinase activity, hyperactivation and acrosome reaction in human spermatozoa

(2012) V. Sagare-Patil et al.   INTERNATIONAL JOURNAL OF ANDROLOGY

Human spermatozoa possess a calcium-dependent chloride channel that may participate in the acrosomal reaction

(2012) Gerardo Orta et al.   JOURNAL OF PHYSIOLOGY-LONDON

Significant Expression Levels of Transgenic PPP1CC2 in Testis and Sperm Are Required to Overcome the Male Infertility Phenotype of Ppp1cc Null Mice

(2012) Nilam Sinha et al.   PLoS One

Ion channels, phosphorylation and mammalian sperm capacitation

(2011) Pablo E Visconti et al.   ASIAN JOURNAL OF ANDROLOGY

Identification of the human testis protein phosphatase 1 interactome

(2011) Margarida Fardilha et al.   BIOCHEMICAL PHARMACOLOGY

Hyper-activated motility in sperm capacitation is mediated by Phospholipase D-dependent actin polymerization

(2011) Sarit Bar-Sheshet Itach et al.   DEVELOPMENTAL BIOLOGY

Multidrug Resistance Protein 4 (MRP4/ABCC4) Regulates cAMP Cellular Levels and Controls Human Leukemia Cell Proliferation and Differentiation

(2011) Sabrina Copsel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein phosphatase 1 complexes modulate sperm motility and present novel targets for male infertility

(2011) M. Fardilha et al.   MOLECULAR HUMAN REPRODUCTION

Progesterone activates the principal Ca2+ channel of human sperm

(2011) Polina V. Lishko et al.   NATURE

The CatSper channel mediates progesterone-induced Ca2+ influx in human sperm

(2011) Timo Strünker et al.   NATURE

Inhibition of Ser/Thr Phosphatases Induces Capacitation-associated Signaling in the Presence of Src Kinase Inhibitors

(2010) Dario Krapf et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Src kinase up-regulates the ERK cascade through inactivation of protein phosphatase 2A following cerebral ischemia

(2009) Xiaohan Hu et al.   BMC NEUROSCIENCE

Phosphorylation and consequent stimulation of the tyrosine kinase c-Abl by PKA in mouse spermatozoa; its implications during capacitation

(2009) Mark A. Baker et al.   DEVELOPMENTAL BIOLOGY

Expression of full-length and truncated Fyn tyrosine kinase transcripts and encoded proteins during spermatogenesis and localization during acrosome biogenesis and fertilization

(2009) Abraham L. Kierszenbaum et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Increased Activity of the Human Sperm Tyrosine Kinase SRC by the cAMP-Dependent Pathway in the Presence of Calcium1

(2008) Christine Lawson et al.   BIOLOGY OF REPRODUCTION

Src activation triggers capacitation and acrosome reaction but not motility in human spermatozoa

(2008) G. Varano et al.   HUMAN REPRODUCTION

Investigation of the role of SRC in capacitation-associated tyrosine phosphorylation of human spermatozoa

(2008) Lisa A. Mitchell et al.   MOLECULAR HUMAN REPRODUCTION