Active DNA demethylation in mammalian preimplantation embryos: new insights and new perspectives

Assisted reproduction treatment and epigenetic inheritance

(2012) A.P.A. van Montfoort et al.   HUMAN REPRODUCTION UPDATE

Thymine DNA Glycosylase Is Essential for Active DNA Demethylation by Linked Deamination-Base Excision Repair

(2011) Salvatore Cortellino et al.   CELL

Hydroxylation of 5-Methylcytosine by TET1 Promotes Active DNA Demethylation in the Adult Brain

(2011) Junjie U. Guo et al.   CELL

Lineage-specific distribution of high levels of genomic

(2011) Alexey Ruzov et al.   CELL RESEARCH

Tet1 Is Dispensable for Maintaining Pluripotency and Its Loss Is Compatible with Embryonic and Postnatal Development

(2011) Meelad M. Dawlaty et al.   Cell Stem Cell

Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells

(2011) H. Wu et al.   GENES & DEVELOPMENT

Thymine DNA Glycosylase Can Rapidly Excise 5-Formylcytosine and 5-Carboxylcytosine

(2011) Atanu Maiti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Embryonic lethal phenotype reveals a function of TDG in maintaining epigenetic stability

(2011) Daniel Cortázar et al.   NATURE

The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes

(2011) Tian-Peng Gu et al.   NATURE

Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells

(2011) William A. Pastor et al.   NATURE

Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation

(2011) Gabriella Ficz et al.   NATURE

Sensitive and specific single-molecule sequencing of 5-hydroxymethylcytosine

(2011) Chun-Xiao Song et al.   NATURE METHODS

Mammalian Gcm genes induce Hes5 expression by active DNA demethylation and induce neural stem cells

(2011) Seiji Hitoshi et al.   NATURE NEUROSCIENCE

Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine

(2011) Khursheed Iqbal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Replication-Dependent Loss of 5-Hydroxymethylcytosine in Mouse Preimplantation Embryos

(2011) A. Inoue et al.   SCIENCE

Tet-Mediated Formation of 5-Carboxylcytosine and Its Excision by TDG in Mammalian DNA

(2011) Y.-F. He et al.   SCIENCE

Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine

(2011) S. Ito et al.   SCIENCE

5-Hydroxymethylcytosine in the mammalian zygote is linked with epigenetic reprogramming

(2011) Mark Wossidlo et al.   Nature Communications

Dynamic link of DNA demethylation, DNA strand breaks and repair in mouse zygotes

(2010) Mark Wossidlo et al.   EMBO JOURNAL

Cytidine deaminases: AIDing DNA demethylation?

(2010) E. L. Fritz et al.   GENES & DEVELOPMENT

Active loss of DNA methylation in two-cell stage goat embryos

(2010) Jung S. Park et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Epigenetic Characteristics of Paternal Chromatin in Interspecies Zygotes

(2010) Irena BARNETOVA et al.   JOURNAL OF REPRODUCTION AND DEVELOPMENT

Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency

(2010) Christian Popp et al.   NATURE

A role for the elongator complex in zygotic paternal genome demethylation

(2010) Yuki Okada et al.   NATURE

Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification

(2010) Shinsuke Ito et al.   NATURE

The Behaviour of 5-Hydroxymethylcytosine in Bisulfite Sequencing

(2010) Yun Huang et al.   PLoS One

Genome-Wide Reprogramming in the Mouse Germ Line Entails the Base Excision Repair Pathway

(2010) P. Hajkova et al.   SCIENCE

Epigenetic reprogramming and induced pluripotency

(2009) K. Hochedlinger et al.   DEVELOPMENT

Demethylation Dynamics of the Paternal Genome in Pronuclear-Stage Bovine Zygotes Produced by In Vitro Fertilization and Ooplasmic Injection of Freeze-Thawed or Freeze-Dried Spermatozoa

(2009) Hany ABDALLA et al.   JOURNAL OF REPRODUCTION AND DEVELOPMENT

Effect of IVF and laser zona dissection on DNA methylation pattern of mouse zygotes

(2009) Dominika D. Peters et al.   MAMMALIAN GENOME

Impaired active demethylation of the paternal genome in pronuclear-stage rat zygotes produced by in vitro fertilization or intracytoplasmic sperm injection

(2009) Yusuke Yoshizawa et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

DNA demethylation in hormone-induced transcriptional derepression

(2009) Mi-Sun Kim et al.   NATURE

Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1

(2009) M. Tahiliani et al.   SCIENCE

Long-Term Effects of Mouse Intracytoplasmic Sperm Injection with DNA-Fragmented Sperm on Health and Behavior of Adult Offspring1

(2008) Raúl Fernández-Gonzalez et al.   BIOLOGY OF REPRODUCTION

Functional Analysis of Male Mouse Haploid Germ Cells of Various Differentiation Stages: Early and Late Round Spermatids Are Functionally Equivalent in Producing Progeny1

(2008) Hiroshi Ohta et al.   BIOLOGY OF REPRODUCTION

Epigenetic analysis of human spermatozoa after their injection into ovulated mouse oocytes

(2008) H. Fulka et al.   HUMAN REPRODUCTION

Hypomethylation of paternal DNA in the late mouse zygote is not essential for development

(2008) Zbigniew Polanski et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Cyclical DNA methylation of a transcriptionally active promoter

(2008) Raphaël Métivier et al.   NATURE

Evidence for conserved DNA and histone H3 methylation reprogramming in mouse, bovine and rabbit zygotes

(2008) Konstantin Lepikhov et al.   Epigenetics & Chromatin