期刊
MOLECULAR ENDOCRINOLOGY
卷 26, 期 12, 页码 1957-1960出版社
OXFORD UNIV PRESS INC
DOI: 10.1210/me.2012-1284
关键词
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资金
- Society for Women's Health Research
- National Institutes of Health
- Klarman Foundation
- University of Texas Southwestern
Gonadal steroids are critical regulators of physiology, yet we approach physiology and science with the simplest perspective/model, the male one. Female models of whole animal physiology are complex to study and, therefore, are often not used in research. Estrogens are one of the sex hormones that we know are important for both men and women. Estrogens regulate key features of metabolism such as food intake, body weight, glucose homeostasis/insulin sensitivity, body fat distribution, lipolysis/lipogenesis, inflammation, locomotor activity, energy expenditure, reproduction, and cognition. Furthermore, estrogens have multiple sites of action including some unexpected ones, which was demonstrated elegantly through a series of papers this year. (Molecular Endocrinology 26: 1957-1960, 2012)
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