期刊
MOLECULAR DIVERSITY
卷 16, 期 1, 页码 121-128出版社
SPRINGER
DOI: 10.1007/s11030-011-9336-z
关键词
Fe3O4 nanoparticles; Multicomponent reactions (MCRs); Magnetically separable; N-heterocycles; Diverse synthesis
类别
资金
- UGC, New Delhi
A large library of diversified compounds (pyrano [2,3-d] pyrimidines, pyrido[2,3-d] pyrimidines and a variety of spirooxindoles) were synthesized through a very efficient, economical and environmentally benign process utilizing magnetic nanoparticles. Ease of recovery using an external magnetic field is an additional ecofriendly attribute of this catalytic system. Most of the compounds are new; therefore, could be further explored for their pharmaceutical application. Moreover, column chromatography and recrystallisation of the products is not required as the crude products are already highly pure and hence can be used for target oriented synthesis on a wide scale.
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